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A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity

for
Overweight, Prediabetic State, Prehypertension,
Location: Waterbury CT, Hartsdale NY, Warren Township NJ,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07794579

Phase3, Recruiting
New

A Study of Tris-Hydroxymethyl Aminomethane (THAM) Versus Sodium Bicarbonate in Cardiac Surgical Patients

for
Metabolic Acidosis
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 21+

Code: NCT07424625

Recruiting
New

A Study of Risvutatug Rezetecan in Combination With Ivonescimab in Participants With Advanced Solid Tumors (EMBOLD PanTumour-103)

for
Neoplasms, Lung
Location: Wilson NC, Canton OH, Los Angeles CA
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT07602855

Phase1, Phase2, Recruiting
New

Memantine +/- Raloxifene for Cognitive Preservation After Radiation Therapy to the Brain

for
Brain Tumor
Location: San Antonio TX
Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All

Age: 18+

Code: NCT07470606

Phase2, Recruiting
Active & ResponsiveNew

Leveraging Chatbot to Improve PrEP in the Southern United States

for
HIV Prevention, PrEP Awareness, PrEP Uptake
Location: Miami FL, Pembroke Pines FL, Charlotte NC, Atlanta GA
Sponsor: Yale University

Sex: Male

Age: 18+

Code: NCT05968755

Recruiting

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QUARTZ: Comparative Effectiveness of Switching From Albuterol to Albuterol/Budesonide Versus Adding Low-dose ICS or LTRA to Albuterol

for
Asthma
Location: Wilmington DE
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT07787117

Recruiting
New

Cognitive Rehabilitation for Survivors of Childhood Medulloblastoma Using Real Time Hemodynamic Neurofeedback

for
Medulloblastoma, Childhood, Survivorship
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 10 - 25

Code: NCT07830134

Recruiting
New

Autonomous Artificial Intelligence Versus AI Assisted Human Optical Diagnosis

for
Colonic Polyp, Artificial Intelligence
Location: Montreal
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: All

Age: 45 - 70+

Code: NCT06543862

Recruiting
Active & ResponsiveNew

Effectiveness of an 8-week Independent Cadence Retraining Program on Stress Urinary Incontinence in Parous Runners.

for
Stress Urinary Incontinence
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: Female

Age: 18+

Code: NCT07829692

Recruiting
New

VISTA: Valproic Acid, Irinotecan, and Simvastatin for Recurrent Glioma

for
Glioblastoma, Astrocytoma, IDH-Mutant, Grade 4
Location: Fairfax VA
Sponsor: Inova Health Care Services

Sex: All

Age: 18 - 70+

Code: NCT07831369

Phase2, Recruiting
Active & ResponsiveNew

Developing Biomarker-Supported Schizophrenia Spectrum Disorder (SSD) Prevention

for
Schizophrenia Spectrum Disorders (SSD)
Location: Houston TX
Sponsor: The University of Texas Health Science Center, Houston

Sex: All

Age: 9 - 19

Code: NCT07743645

Recruiting
New

Postoperative Tizanidine Use in Pelvic Reconstructive Surgery: A Pilot Study

for
Post Operative, Post Operative Analgesia,
Location: Hartford CT
Sponsor: Hartford Hospital

Sex: Female

Age: 18 - 70+

Code: NCT07766837

Phase2, Recruiting
New

Dose Optimization and Diagnostic Performance in Prostate Cancer (SPARROW [Staging Prostate Cancer With Advanced RM2 Radiotracer Oncologic Workup])

for
Prostate Cancer
Location: Grand Rapids MI
Sponsor: Lantheus Medical Imaging

Sex: Male

Age: 18+

Code: NCT07831824

Phase2, Phase3, Recruiting
New

Impact of AI Care Summaries on Caregiver Comprehension

for
Health Literacy, Comprehension, Patient Satisfaction
Location: Washington D.C. DC
Sponsor: Children's National Research Institute

Sex: All

Age: 18+

Code: NCT07831018

Recruiting
New

A Clinical Trial of Telehealth Treatment for Opioid Use Disorders

for
Opioid Use Disorder
Location: New Haven CT
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT07362082

Recruiting
New

A Study to Learn How Different Amounts of the Study Medicine Called PF-08642534 Are Tolerated and Act in the Body of People Who Have Obesity

for
Obesity
Location: Lake Forest CA
Sponsor: Pfizer

Sex: All

Age: 18 - 70

Code: NCT07731139

Phase1, Recruiting
New

A Study to Learn About the Study Medicine Called Rimegepant in Adults When Used for the Prevention of Chronic Migraine

for
Preventive Treatment of Migraine
Location: Boca Raton FL, City of Saint Peters MO, Papillion NE,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07729462

Phase3, Recruiting
New

A Study to Assess the Safety, Tolerability, and Immunogenicity of 3 Lots of a Multivalent Pneumococcal Conjugate Vaccine Administered to Adults

for
Pneumococcal Disease
Location: Milford CT, Somers Point NJ, Wilmington NC,
Sponsor: Pfizer

Sex: All

Age: 18 - 49

Code: NCT07794748

Phase3, Recruiting
New

Transition to Ambulatory Bariatric Surgery (TABS) Trial

for
Obesity and Obesity-related Medical Conditions,
Location: Nashville TN
Sponsor: Vanderbilt University Medical Center

Sex: All

Age: 25 - 55

Code: NCT07011628

Recruiting
New

PrEP4U: Assessing the Effectiveness of Integrated Same-Day Lenacapavir Initiation and Follow-up Choice on PrEP Persistence

for
HIV Pre-exposure Prophylaxis Use
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT07335289

Recruiting