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Long-term Safety of Eplontersen Treated aTTR Patients and in Liver Transplant and Severely Hepatic Impaired Subpopulations

for
Transthyretin Amyloidosis,
Location: Vancouver, Los Angeles CA
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07654855

Recruiting
New

Consecutive Occupational Heat Exposure With and Without Overnight Cooling

for
Body Temperature Changes, Heat Stress, Heat Exposure,
Location: Ottawa
Sponsor: University of Ottawa

Sex: Male

Age: 50 - 70

Code: NCT07656519

Recruiting
New

Post-ablation Alcohol Impacts Arrhythmia Recurrence, Quality of Life and Cognition in AF

for
Atrial Fibrillation
Location: Austin TX
Sponsor: Texas Cardiac Arrhythmia Research Foundation

Sex: All

Age: 18 - 70+

Code: NCT05510167

Recruiting
New

Relapse Prevention Trial Evaluating KarXT Treatment in Schizophrenia

for
Schizophrenia
Location: West Palm Beach FL, Hollywood FL, Atlanta GA,
Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All

Age: 18 - 65

Code: NCT07686263

Phase3, Recruiting
Active & ResponsiveNew

Effects of Recursive Self-feedback on Speech Production in Aphasia

for
Aphasia, Stroke
Location: Tampa FL
Sponsor: University of South Florida

Sex: All

Age: 18 - 70+

Code: NCT06323629

Recruiting

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Active & Responsive

Self-balancing Personal Exoskeleton for SCI (WINY)

for
Spinal Cord Injury, Paraplegia and Tetraplegia
Location: New York NY
Sponsor: Wandercraft

Sex: All

Age: 18+

Code: NCT07222033

Recruiting
New

iDose TR Administration in an Office-Based Surgery Setting

for
Open Angle Glaucoma (OAG), Ocular Hypertension (OHT)
Location: Austin TX
Sponsor: Glaukos Corporation

Sex: All

Age: 18+

Code: NCT07816692

Recruiting
Active & ResponsiveNew

Outcomes of Neurosurgical Tone Management

for
Spastic/Dystonic Quadriplegia, Cerebral Palsy (CP)
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 6 - 25

Code: NCT07817745

Recruiting
New

BOND: Direct Breastfeeding to Enhance Maternal and Infant Health in Congenital Heart Disease

for
Congenital Heart Disease (CHD)
Location: Charleston SC, Atlanta GA, Ann Arbor MI, Cincinnati OH,
Sponsor: Carelon Research

Sex: All

Age: 18+

Code: NCT07582848

Recruiting
New

Vorasidenib Maintenance for IDH Mutant Astrocytoma

for
IDH-mutant Grade 2 or 3 Astrocytoma
Location: Winnipeg
Sponsor: European Organisation for Research and Treatment of Cancer - EORTC

Sex: All

Age: 18+

Code: NCT06809322

Phase3, Recruiting
New

Virtual Reality for Pain and Well-Being in Older Adults

for
Chronic Pain, Kinesiophobia (Fear of Movement)
Location: Sainte-Marie, Quebec
Sponsor: Laval University

Sex: All

Age: 65+

Code: NCT07607899

Recruiting
New

NIRAF-camera Versus Conventional Surgery in Preoperative Imaging Negative Primary Hyperparathyroidism

for
Primary Hyperparathyroidism
Location: Cleveland OH
Sponsor: The Cleveland Clinic

Sex: All

Age: 18+

Code: NCT07812649

Recruiting
New

Robotic Adrenalectomy With Versus Without Indocyanine Green Fluorescence Imaging

for
Adrenalectomy
Location: Cleveland OH
Sponsor: The Cleveland Clinic

Sex: All

Age: 18+

Code: NCT07813247

Recruiting
New

A First-in-Human Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of HMB-003 in Healthy Volunteers

for
Healthy Adult Participants
Location: San Antonio TX
Sponsor: Hemab ApS

Sex: All

Age: 18 - 50

Code: NCT07798505

Phase1, Recruiting
New

A Phase 2 Study of NT-101 Topical in Patients With Wet AMD

for
Wet Age Related Macular Degeneration
Location: Bonita Springs FL, Erie PA, Tulsa OK
Sponsor: NexThera Co., Ltd.

Sex: All

Age: 50+

Code: NCT07811726

Phase2, Recruiting
New

A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease

for
Alzheimer's Disease
Location: Laurelton NY, Toronto, Maitland FL, Santa Ana CA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 55 - 70+

Code: NCT07717411

Phase3, Recruiting
New

Immersive Virtual Reality for Older Adults in Long-Term Care Settings

for
Cognitive Impairment,
Location: Sainte-Marie, Quebec
Sponsor: Laval University

Sex: All

Age: 60+

Code: NCT07658287

Recruiting
New

Interventions to Enhance Quadriceps Output After ACLR

for
ACL
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: All

Age: 18 - 40

Code: NCT07674784

Recruiting
New

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ONO-6414 Administered Orally in Healthy Adult Participants and Patients With Active Ulcerative Colitis

for
Ulcerative Colitis (UC)
Location: Miami FL
Sponsor: Ono Pharmaceutical Co., Ltd.

Sex: All

Age: 18 - 55

Code: NCT07749768

Phase1, Recruiting
New

A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes

for
Diabetes Mellitus, Type 2
Location: Charlottesville VA, Boynton Beach FL, Tamarac FL,
Sponsor: Novo Nordisk A/S

Sex: All

Age: 10 - 18

Code: NCT07282613

Phase3, Recruiting