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Multi-strain Probiotic Supplement for Digestive Comfort and Well-being in Healthy Women

for
Gastrointestinal Discomfort, Bloating
Location: San Francisco CA
Sponsor: Daily Nouri

Sex: Female

Age: 25 - 45

Code: NCT07831317

Recruiting
New

A Study to Investigate the Efficacy and Safety of GSK5784283 Compared With Placebo in Participants With Uncontrolled Asthma (PERSIST ASTHMA-1)

for
Asthma
Location: Miami Lakes FL
Sponsor: GlaxoSmithKline

Sex: All

Age: 12 - 70+

Code: NCT07780643

Phase3, Recruiting
New

A Phase III Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With CKD Stage 3b and 4 (BalanceD-CKD)

for
Renal Insufficiency, Chronic
Location: Savannah GA, Charlotte NC, Waterloo, Riverview FL,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT07624305

Phase3, Recruiting
Active & ResponsiveNew

TRAIL-R2 and HER2 Bi-Specific Chimeric Antigen Receptor (CAR) T Cells for the Treatment of Metastatic Breast Cancer

for
Breast Cancer, Tumor, Breast, Breast Tumor,
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: All

Age: 18 - 70+

Code: NCT06251544

Phase1, Recruiting
Active & ResponsiveNew

Insomnia and Insulin Resistance

for
Insomnia, Insulin Resistance
Location: Columbia MO
Sponsor: University of Missouri-Columbia

Sex: All

Age: 18 - 50

Code: NCT07333586

Recruiting

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Comparison of Hand Eye Coordination and Sports Vision Performance in Dual-Focus Multifocal Contact Lenses and Habitual Contact Lenses

for
Myopia
Location: Columbus OH
Sponsor: Ohio State University

Sex: All

Age: 18 - 38

Code: NCT07840209

Recruiting
New

Evaluation of the Safety and Effects of Psychoactive Substances in People With Past Opioid Use

for
Opioid Use, Substance Use Disorders, Opioid Analgesia
Location: Houston TX
Sponsor: Christopher D. Verrico

Sex: All

Age: 18 - 55

Code: NCT07218549

Phase1, Recruiting
Active & ResponsiveNew

Developing New Ways to Detect Respiratory Impairment Early in ALS

for
Amyotrophic Lateral Sclerosis (ALS)
Location: Philadelphia PA
Sponsor: Thomas Jefferson University

Sex: All

Age: 18+

Code: NCT07844590

Recruiting
Active & ResponsiveNew

ACT for Dementia Caregivers: Evaluating Psychological Flexibility as the Mechanism to Improve Psychological Distress

for
Dementia Caregivers
Location: Logan UT
Sponsor: Utah State University

Sex: All

Age: 18+

Code: NCT07845032

Recruiting
New

A Study to Evaluate the Safety and Pharmacokinetics of Multiple Doses Upadacitinib, Tofacitinib, and Baricitinib in Healthy Adult Volunteers

for
Healthy Volunteers
Location: Grayslake IL
Sponsor: AbbVie

Sex: All

Age: 18 - 65

Code: NCT07843693

Phase1, Recruiting
Active & ResponsiveNew

A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-005)

for
Diabetic Retinopathy, Macular Edema
Location: Charleston SC, Winter Haven FL, Katy TX, Arlington TX,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07705607

Phase3, Recruiting
New

Efficacy and Safety of VER-01 in the Treatment of Participants With Chronic Painful Lumbosacral Radiculopathy

for
Lumbosacral Radiculopathy
Location: Katy TX
Sponsor: Vertanical GmbH

Sex: All

Age: 18+

Code: NCT06956014

Phase3, Recruiting
Active & ResponsiveNew

An Open-Label, Safety and Efficacy Study of Cebranopadol in Participants With Acute Pain With Surgical or Non-Surgical Origin

for
Pain
Location: Oradell NJ, Annapolis MD, Tulsa OK, Forney TX,
Sponsor: Adneuris Therapeutics, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07845071

Phase3, Recruiting
New

Low-Dose Sirolimus for the Treatment of RUNX1 Familial Platelet Disorder

for
Familial Platelet Disorder With Associated Myeloid Malignancy
Location: Portland OR
Sponsor: OHSU Knight Cancer Institute

Sex: All

Age: 18+

Code: NCT07844694

Early_phase1, Recruiting
New

Velocity-Loss Training and Parkinson's Disease

for
Activity, Motor
Location: Coral Gables FL
Sponsor: University of Miami

Sex: All

Age: 50 - 70+

Code: NCT07840508

Recruiting
Active & ResponsiveNew

Older Breast Cancer Patients: Risk for Cognitive Decline

for
Cancer, Breast, Age-related Cognitive Decline,
Location: Washington D.C. DC
Sponsor: Georgetown University

Sex: Female

Age: 60 - 70+

Code: NCT03451383

Recruiting
New

Diabetes, Insulin, Gut, Enteric Supplementation Trial

for
Gestational Diabetes Mellitus (GDM), Blood Glucose,
Location: Fredericton
Sponsor: University of New Brunswick

Sex: Female

Age: 19+

Code: NCT07682077

Recruiting
New

Randomized Study to Evaluate the Effect of Obicetrapib in Participants With Preclinical Alzheimer's Disease

for
Preclinical Alzheimer's Disease
Location: Nashville TN
Sponsor: NewAmsterdam Pharma

Sex: All

Age: 55 - 70+

Code: NCT07794670

Phase2, Recruiting
New

CHAMPION: A Study to Evaluate the Efficacy and Safety of Obudanersen (ION582) in Children and Adults With Angelman Syndrome (AS)

for
Angelman Syndrome
Location: Carrboro NC
Sponsor: Ionis Pharmaceuticals, Inc.

Sex: All

Age: 2 - 50

Code: NCT07782827

Phase3, Recruiting
New

Feeding the Flame, One Day at a Time: Design and Acceptability of a Serious Game to Support Medication Adherence and Education for Pediatric Solid Organ Transplant Patients

for
Solid Organ Transplant
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 7 - 17

Code: NCT07609303

Recruiting