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Alcohol Use Disorder Clinical Trials

Browse 309 Alcohol Use Disorder clinical trials enrolling across the United States and Canada. 63 people applied to Alcohol Use Disorder studies last month. Search by city or state to find one near you.

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Active & Responsive

Tirzepatide in MetALD

for
Metabolic Alcohol-associated Liver Disease,
Location: Bethesda MD
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Sex: All

Age: 21 - 70+

Code: NCT07046819

Phase2, Recruiting
Active & Responsive

Cannabidiol and Alcohol Use Disorder Phenotypes

for
Alcohol Use Disorder
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 21 - 65

Code: NCT07279558

Phase2, Recruiting
Active & Responsive

Probenecid Administration for Alcohol Craving and Consumption

for
Alcohol Use Disorder (AUD), Alcohol Consumption, Craving
Location: Providence RI
Sponsor: Brown University

Sex: All

Age: 18+

Code: NCT07118618

Phase2, Recruiting
Active & Responsive

Phase 2 Study of Apremilast in Women and Men With Alcohol Use Disorder

for
Alcohol Use Disorder
Location: New Haven CT
Sponsor: Yale University

Sex: All

Age: 21 - 65

Code: NCT07029529

Phase2, Recruiting
Active & Responsive

Suvorexant for Treatment of AUD and PTSD

for
Alcohol Use Disorder (AUD),
Location: Houston TX, Los Angeles CA
Sponsor: Pharmacotherapies for Alcohol and Substance Use Disorders Alliance

Sex: All

Age: 21 - 65

Code: NCT06679062

Phase2, Recruiting

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Active & Responsive

Alcohol Treatment Outcomes Following Early vs. Standard Liver Transplant for SAH

for
Alcohol Use Disorder, Alcoholic Hepatitis
Location: Baltimore MD
Sponsor: Johns Hopkins University

Sex: All

Age: 18+

Code: NCT03845205

Recruiting
Active & Responsive

Motivation for IV Alcohol Self-Administration in Humans

for
Alcohol Use Disorder
Location: Los Angeles CA
Sponsor: University of California, Los Angeles

Sex: All

Age: 21 - 65

Code: NCT06494891

Phase2, Recruiting
Active & Responsive

Mechanistic Evaluation of Guanfacine on Drinking Behavior in Women and Men With Alcohol Use Disorders

for
Alcohol Use
Location: New Haven CT
Sponsor: Yale University

Sex: All

Age: 21 - 70

Code: NCT03764098

Phase2, Recruiting
Active & Responsive

Temporal Interference Methods for Addiction Treatment

for
Nicotine Use Disorder, Substance Use Disorders
Location: Indianapolis IN, Bloomington IN
Sponsor: Indiana University

Sex: All

Age: 21 - 50

Code: NCT07210268

Recruiting
Active & Responsive

Individualized Adaptive Deep Brain Stimulation in Opioid Use Disorder

for
Substance Use Disorder (SUD), Opioid Use Disorder (OUD)
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 22 - 70+

Code: NCT07214467

Recruiting
Active & Responsive

Project COMET: Massed Prolonged Exposure for PTSD and SUD

for
Posttraumatic Stress Disorder (PTSD),
Location: Jacksonville FL
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 18+

Code: NCT06968832

Recruiting
Active & Responsive

Defining Neurobiological Links Between Substance Use and Mental Illness

for
Major Depressive Disorder, Substance Use Disorder,
Location: Baltimore MD
Sponsor: National Institute on Drug Abuse (NIDA)

Sex: All

Age: 18 - 60

Code: NCT05538910

Recruiting
Active & Responsive

Open-Label Psilocybin Study in Transdiagnostic Population

for
Transdiagnostic, Depression - Major Depressive Disorder,
Location: New Haven CT
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT06442423

Phase1, Recruiting
Active & Responsive

Shared Decision Making to Treat Or Prevent (STOP) HIV in Criminal Legal Involved Populations (R33)

for
Substance Use Disorders
Location: New Haven CT, Lexington KY, Dallas TX, Fort Worth TX
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT07223398

Recruiting
Active & Responsive

Neuroimaging of Adolescent Cannabis Use Treatment

for
Cannabis Use, Cannabis Dependence, Cannabis Use Disorder,
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 14 - 17

Code: NCT07340554

Recruiting
Active & Responsive

Smartphone-based Intervention for Young Adults With ADHD

for
Attention Deficit/Hyperactivity Disorder(ADHD), Alcohol Use
Location: Pittsburgh PA
Sponsor: Traci Kennedy

Sex: All

Age: 18 - 25

Code: NCT07654205

Recruiting
Active & Responsive

STEPS: Substance Use Trial of E-cigarettes or Pharmacotherapy for Smoking

for
Tobacco Use, Substance Use Disorders
Location: Conway SC, Charleston SC, Greenville SC, Pickens SC
Sponsor: Medical University of South Carolina

Sex: All

Age: 21+

Code: NCT06922617

Recruiting
Active & Responsive

Finding Emotional Empowerment and Lifelong Strength

for
Trauma and Stressor Related Disorders, Substance Use
Location: Piscataway NJ
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 18 - 35

Code: NCT07378254

Recruiting
Active & Responsive

Mindfulness-based Relapse Prevention for Peer Workers

for
Relapse/Recurrence, Substance Use (Drugs, Alcohol), Burnout
Location: Austin TX
Sponsor: University of Texas at Austin

Sex: All

Age: 18 - 70+

Code: NCT07741825

Recruiting
Active & Responsive

Couples Motivational Interviewing to Reduce Drug Use and HIV Risk in Vulnerable Male Couples

for
Substance Use, HIV Infections
Location: New York NY
Sponsor: Hunter College of City University of New York

Sex: Male

Age: 18 - 55

Code: NCT06307977

Recruiting

What are Alcohol Use Disorder clinical trials?

Alcohol Use Disorder (AUD) clinical trials are research studies that look at different ways to help people reduce drinking, manage cravings, and support long-term recovery. Researchers use these studies to better understand how people respond differently to various kinds of support, and how factors like genetics, mental health, and daily life circumstances affect recovery over time.

The importance of clinical trials in Alcohol Use Disorder research

Alcohol clinical trials are an important part of how alcohol use disorder is understood and addressed more broadly. They help researchers learn why drinking patterns differ from person to person and what kind of support actually helps at different stages of recovery. One recent trial, for example, found that people given weekly semaglutide, a medication originally developed for diabetes and weight management, had 41% fewer heavy drinking days over 26 weeks than those given a placebo, showing that clinical trials can uncover meaningful ways to reduce drinking, even from medications not originally designed for this purpose. This work also helps shape recovery support and public health efforts nationwide.

Who can participate in Alcohol Use Disorder clinical trials?

Types of Alcohol Use Disorder clinical trials

Does information stay confidential when participating in an Alcohol Use Disorder clinical trial?

How to enroll in a clinical trial for Alcohol Use Disorder