Browse 1,747 esophageal cancer clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.
There are two main types of esophageal cancer, and in the United States the more common one is now adenocarcinoma, linked to long term acid reflux and a condition called Barrett's esophagus. Because the esophagus stretches easily, symptoms such as trouble swallowing often appear only after the cancer has grown. Outcomes improve most when cancer is found early and treated with combinations, and trials are testing immunotherapy, targeted drugs, and better ways to spot cancer in people with Barrett's esophagus before it develops.
Erlotinib in Treating Patients With Barrett Esophagus
for
Esophageal Cancer, Precancerous Condition
Location: Kansas City MO
Sponsor: Kansas City Veteran Affairs Medical Center
Sex: All
Age: 18+
Code: NCT00566800
Phase 1, Recruiting
Outcomes After Esophagectomy With a Focus on Minimally Invasive Esophagectomy and Quality of Life
for
Esophagectomy, Esophageal Cancer
Location: Pittsburgh PA
Sponsor: University of Pittsburgh
Sex: All
Age: 18+
Code: NCT00260559
Recruiting
Trans-Pacific Multicenter Collaborative Study of Minimally Invasive Proximal Versus Total Gastrectomy for Proximal Gastric and Gastroesophageal Junction Cancers
for
Gastrostomy, Gastric, GastroEsophageal Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center
Sex: All
Age: 18+
Code: NCT05205343
Recruiting
A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer
Location: Sayre PA, West Palm Beach FL, Pompano Beach FL,
Sponsor: Shanghai Henlius Biotech
Sex: All
Age: 18+
Code: NCT06532006
Phase 3, Recruiting
A Study of MT-4561 in Patients With Various Advanced Solid Tumors
for
Head and Neck Squamous Cell Carcinoma (HNSCC),
Location: Columbus OH, Grand Rapids MI, Houston TX,
Sponsor: Tanabe Pharma America, Inc.
Sex: All
Age: 18+
Code: NCT06943521
Phase 1, Phase 2, Recruiting
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Ontario-wide Cancer TArgeted Nucleic Acid Evaluation
for
Breast Cancer, Lung Cancer, Colorectal Cancer, Melanoma,
Location: Ottawa, Toronto
Sponsor: University Health Network, Toronto
Sex: All
Age: 18+
Code: NCT02906943
Recruiting
Fatigue and Molecular Mechanisms in Cancer Patients Receiving CCRT
for
Cancer, Thoracic Cancer, Gynecologic Cancer,
Location: San Francisco CA
Sponsor: University of California, San Francisco
Sex: All
Age: 18+
Code: NCT06633224
Recruiting
Cancer Genetic Testing in Ethnic Populations
for
Breast Carcinoma, Carcinoma of Unknown Primary,
Location: Jacksonville FL, Scottsdale AZ
Sponsor: Mayo Clinic
Sex: All
Age: 18+
Code: NCT04475640
Recruiting
MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid Tumors
for
Solid Tumor, Advanced Cancer, Metastatic Cancer,
Location: Tampa FL
Sponsor: Memgen, Inc.
Sex: All
Age: 18+
Code: NCT05076760
Phase 1, Recruiting
Study of High-Precision Evaluation of Molecular ResiduaL Disease Through a PlatfOrm for Cancer TracKing and Interception (SHERLOCK)
for
Breast Cancer, Lung Cancer, Melanoma, Gynecologic Cancer,
Location: Toronto
Sponsor: University Health Network, Toronto
Sex: All
Age: 18+
Code: NCT07524114
Recruiting
Adapting the Tumor Board Model for Mental Illness and Cancer
for
Cancer, Severe Major Depression, Schizophrenia,
Location: Danvers MA
Sponsor: Massachusetts General Hospital
Sex: All
Age: 18+
Code: NCT05837598
Recruiting
Prospective Data Registry and Quality of Life Assessment of Patients Undergoing Radiotherapy With the RefleXion Medical Radiotherapy System
for
Cancer, Cancer Central Nervous System, Cancer Thoracic,
Location: New Haven CT, Pittsburgh PA, Dallas TX, Duarte CA,
Sponsor: RefleXion Medical
Sex: All
Age: 0+
Code: NCT05406167
Recruiting
Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors
for
Anatomic Stage III Breast Cancer AJCC v8,
Location: Jacksonville FL
Sponsor: Mayo Clinic
Sex: All
Age: 16+
Code: NCT05269381
Phase 1, Phase 2, Recruiting
Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors
for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center
Sex: All
Age: 18+
Code: NCT04771520
Phase 2, Recruiting
Testing the Combination of the Anticancer Drugs Trastuzumab Deruxtecan (DS-8201a) and Azenosertib (ZN-c3) in Patients With Stomach or Other Solid Tumors
for
Clinical Stage III Gastric Cancer AJCC v8,
Location: Houston TX
Sponsor: National Cancer Institute (NCI)
Sex: All
Age: 18+
Code: NCT06364410
Phase 1, Recruiting
RAPA-201 Therapy of Solid Tumors
for
Solid Tumor, Small Cell and Non-small Cell Lung Cancer,
Location: Hackensack NJ
Sponsor: Rapa Therapeutics LLC
Sex: All
Age: 18+
Code: NCT05144698
Phase 1, Phase 2, Recruiting
New
SumMET: Study of [225Ac]Ac-FL-261 in Participants With Solid Tumors Overexpressing c-MET
for
Solid Tumor, NSCLC, Colorectal Cancer, Head and Neck Cancer,
Location: Minneapolis MN
Sponsor: Full-Life Technologies UK Limited
Sex: All
Age: 18+
Code: NCT07873450
Phase 1, Phase 2, Recruiting
The Use of Botulinum Toxin A in Two-Stage Tissue Expander/ Implant Breast Reconstruction
for
Breast Neoplasms, Neoplasms by Site, Neoplasms, Breast Diseases,
Location: Surrey, Vancouver
Sponsor: University of British Columbia
Sex: Female
Age: 21+
Code: NCT01427400
Recruiting
Avera Cancer Sequencing and Analytics Protocol (ASAP)
for
Cancer, Cancer Diagnosis, Early Detection of Cancer,