Browse 1,747 esophageal cancer clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.
There are two main types of esophageal cancer, and in the United States the more common one is now adenocarcinoma, linked to long term acid reflux and a condition called Barrett's esophagus. Because the esophagus stretches easily, symptoms such as trouble swallowing often appear only after the cancer has grown. Outcomes improve most when cancer is found early and treated with combinations, and trials are testing immunotherapy, targeted drugs, and better ways to spot cancer in people with Barrett's esophagus before it develops.
Adding Spatially Fractionated Radiation Therapy to Standard Palliative Radiation for Improving Disease-Related Symptoms in Patients With Unresectable Solid Tumors
for
Metastatic Malignant Solid Neoplasm,
Location: Rochester MN, Scottsdale AZ
Sponsor: Mayo Clinic
Sex: All
Age: 15+
Code: NCT07856394
Recruiting
Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)
for
Solid Tumor, Non-Small Cell Lung Cancer, Head and Neck Cancer,
Location: Orange City FL, Clermont FL, Detroit MI, Louisville KY,
Sponsor: Inhibrx Biosciences, Inc
Sex: All
Age: 18+
Code: NCT04198766
Phase 1, Phase 2, Recruiting
Testing the Combination of the Anticancer Drugs ZEN003694 and Binimetinib in Patients With Advanced/Metastatic or Unresectable Solid Tumors With RAS Alterations and Triple Negative Breast Cancer
for
Advanced Malignant Solid Neoplasm,
Location: Houston TX
Sponsor: National Cancer Institute (NCI)
Sex: All
Age: 18+
Code: NCT05111561
Phase 1, Recruiting
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Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene
for
Metastatic Malignant Solid Neoplasm,
Location: Boston MA, Pittsburgh PA, Gainesville FL, Columbus OH,
Sponsor: National Cancer Institute (NCI)
Sex: All
Age: 18+
Code: NCT05372614
Phase 1, Recruiting
FORTRAS: A Study of MSK-TCR5 in People With Solid Tumor Cancers
Location: Fairfax VA, Plantation FL, Austin TX, San Antonio TX
Sponsor: Conjupro Biotherapeutics, Inc.
Sex: All
Age: 18+
Code: NCT07424547
Phase 1, Recruiting
Phase 1b Trial of BMS-986504 in Combination With Olaparib in Patients With MTAP Loss
for
Advanced Cancer, Solid Tumor
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center
Sex: All
Age: 18+
Code: NCT07382544
Phase 1, Recruiting
An 8-Week Study Evaluating Gut and Digestive Health After Use of a Dietary Supplement System
for
Gastrointestinal Symptoms, Digestive Health, Gut Health
Location: San Francisco CA
Sponsor: SF Research Institute, Inc.
Sex: All
Age: 18 - 70+
Code: NCT07421596
Recruiting
WellSpan-THRIVE Cancer QOL Study
for
Cancer (Active Cancer, Meaning Not Being Cancer Free), of Any Stage and Involving Any Treatment/Care Regimen; i.e. Curative, Life-extending, or Palliative,
Location: Ephrata PA, Lebanon PA, York PA, Gettysburg PA,
Sponsor: WellSpan Health
Sex: All
Age: 18+
Code: NCT07433660
Recruiting
DESCANSO, a Mental Health Intervention for Depression, Insomnia, and Fatigue Symptoms in Latino People With Cancer
for
Solid Tumor, Solid Tumor, Adult
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Ponce Medical School Foundation, Inc.
Sex: All
Age: 21 - 70+
Code: NCT07225088
Recruiting
Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies (ELEPHAS-05)