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Esophageal Cancer Clinical Trials

Browse 226 esophageal cancer clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

for
Solid Tumors, Advanced Cancer, Renal Cancer, Gastric Cancer,
Location: Montreal, Hershey PA, Chapel Hill NC, Toronto,
Sponsor: Apollomics Inc.

Sex: All

Age: 18+

Code: NCT03175224

Phase 2, Recruiting

Surveillance vs. Endoscopic Therapy for Barrett's Esophagus With Low-grade Dysplasia

for
Barretts Esophagus With Dysplasia, Barrett Esophagus,
Location: Boston MA, Lebanon NH, Manhasset NY, New York NY,
Sponsor: University of Colorado, Denver

Sex: All

Age: 18 - 70+

Code: NCT05753748

Recruiting

Robotic Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy for Treatment of Gastric Cancer With Limited Peritoneal Metastasis, ROBO-CHIP Study

for
Gastric Adenocarcinoma,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18 - 70+

Code: NCT05753306

Phase 2, Recruiting

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

for
Colorectal Neoplasms, Carcinoma, Non-Small-Cell Lung,
Location: Boston MA, Montreal, Baltimore MD, Ottawa, Toronto,
Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All

Age: 18+

Code: NCT06131840

Phase 1, Recruiting

Oral TGF-beta Receptor I Inhibitor Vactosertib in SOC Chemoradiotherapy for Esophageal Adenocarcinoma

for
Adenocarcinoma Esophagus, Locally Advanced Adenocarcinoma,
Location: Cleveland OH
Sponsor: Melissa Lumish

Sex: All

Age: 18+

Code: NCT06044311

Phase 2, Recruiting

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The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

for
Amyloidosis, Basal Cell Carcinoma, Biliary Tract Carcinoma,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07285044

Phase 2, Recruiting

Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity

for
Gastric Adenocarcinoma,
Location: Westerly RI, Waterford CT, Guilford CT, North Haven CT,
Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All

Age: 18+

Code: NCT07001748

Phase 2, Phase 3, Recruiting

A Study of ASP2138 Together With Chemotherapy and Pembrolizumab in Adults With Gastric Cancer

for
Gastric Adenocarcinoma,
Location: Saint Louis Park MN
Sponsor: Astellas Pharma Global Development, Inc.

Sex: All

Age: 18+

Code: NCT07673887

Phase 3, Recruiting

A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

for
Metastatic Gastric Adenocarcinoma,
Location: Westbrook ME, Florham Park NJ, Flemington NJ,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT07043400

Phase 3, Recruiting

Esomeprazole and Radiation Induced Esophagitis

for
Radiation Esophagitis, Locally Advanced Lung Carcinoma
Location: Chicago IL
Sponsor: Rush University Medical Center

Sex: All

Age: 18+

Code: NCT06120803

Phase 2, Recruiting
New

A Study of MGC030 in Participants With Advanced Solid Tumors

for
Urothelial Cancer, GastroEsophageal Cancer, Colorectal Cancer,
Location: Lake Success NY
Sponsor: MacroGenics

Sex: All

Age: 18+

Code: NCT07822399

Phase 1, Recruiting

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan

for
Non-Small Cell Lung Cancer,
Location: Montreal, Fairfax VA, Durham NC, Toronto,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT05005403

Phase 1, Recruiting

Tethered Capsule Endoscope in Screening Participants for Barrett Esophagus

for
Esophageal Cancer, Precancerous Condition
Location: Seattle WA
Sponsor: US Department of Veterans Affairs

Sex: All

Age: 18 - 70+

Code: NCT00903136

Phase 1, Phase 2, Recruiting

Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma

for
Stomach Cancer, Gastro-Esophageal(GE) Junction Cancer,
Location: Stanford CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT01048281

Recruiting

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

for
Biliary Tract Cancer, Breast Cancer, Cervical Cancer,
Location: Boston MA, Miami FL, Denver CO, Nashville TN,
Sponsor: ModeX Therapeutics, An OPKO Health Company

Sex: All

Age: 18+

Code: NCT06239194

Phase 1, Phase 2, Recruiting

Pharmacologic Therapies to Mitigate Radiation- Associated Heart Disease

for
Chest Wall Tumor, Breast Cancer, Lung Cancer, Esophageal Cancer,
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07685938

Phase 2, Recruiting

Single Dose Investigator Initiated Pilot Study to Investigate CYTALUX (Pafolacianine) for Intraoperative Detection of Malignant Tissue in Subjects Undergoing Surgical Resection for Cancer.

for
Esophageal Cancer, Gastrointestinal Cancers,
Location: Dallas TX
Sponsor: John Waters

Sex: All

Age: 18+

Code: NCT07039526

Phase 2, Recruiting

A Phase 1 Study of IM-1617 in Participants With Advanced Cancer

for
Colorectal Cancer, Non-Small Cell Lung Cancer, Breast Cancer,
Location: Boston MA, New Haven CT, Sarasota FL, Houston TX,
Sponsor: Immunome, Inc.

Sex: All

Age: 18+

Code: NCT07578571

Phase 1, Recruiting

Interventional Endoscopy Database for Pancreatico-biliary, Gastrointestinal and Esophageal Disorders

for
Ampullary Cancer, Duodenal Cancer, Bile Duct Cancer,
Location: New York NY
Sponsor: Weill Medical College of Cornell University

Sex: All

Age: 18+

Code: NCT01438385

Recruiting

A Study of MGC026 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumor, Advanced Cancer, Metastatic Cancer,
Location: Lake Success NY, Grand Rapids MI, Houston TX,
Sponsor: MacroGenics

Sex: All

Age: 18+

Code: NCT06242470

Phase 1, Recruiting