Browse 1,747 esophageal cancer clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.
There are two main types of esophageal cancer, and in the United States the more common one is now adenocarcinoma, linked to long term acid reflux and a condition called Barrett's esophagus. Because the esophagus stretches easily, symptoms such as trouble swallowing often appear only after the cancer has grown. Outcomes improve most when cancer is found early and treated with combinations, and trials are testing immunotherapy, targeted drugs, and better ways to spot cancer in people with Barrett's esophagus before it develops.
Location: New York NY, Jacksonville FL, Ann Arbor MI, Chicago IL,
Sponsor: Novartis Pharmaceuticals
Sex: All
Age: 18+
Code: NCT06401356
Phase 3, Recruiting
Testing A New Anti-cancer Drug Combination, Entinostat and ZEN003694, for Advanced and Refractory Solid Tumors
for
Advanced Malignant Solid Neoplasm,
Location: New Haven CT, Gainesville FL, Oklahoma City OK
Sponsor: National Cancer Institute (NCI)
Sex: All
Age: 18+
Code: NCT05053971
Phase 1, Phase 2, Recruiting
Phase 1 Study of Intratumoral Administration of VAX014 With Expansion in Combination With a Checkpoint Inhibitor in Subjects With Advanced Solid Tumors
for
Advanced Solid Tumor,
Location: Boston MA, Lebanon NH, Morristown NJ,
Sponsor: Vaxiion Therapeutics
Sex: All
Age: 18+
Code: NCT05901285
Phase 1, Recruiting
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Intratumoral Delivery of Viral Replicon (saRNA) Particles Expressing IL-12 in Head and Neck Cancer
for
Head and Neck Cancers- Squamous Cell, Head and Neck Cancer,
Location: Stanford CA
Sponsor: VLP Therapeutics
Sex: All
Age: 18+
Code: NCT06736379
Phase 1, Recruiting
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
A Study to Assess Adverse Events, Change in Disease Activity and How Intravenous ABBV-253 Moves Through the Body in Adult Participants With Advanced Solid Tumors
Location: Huntersville NC, Grand Rapids MI, Irving TX
Sponsor: AbbVie
Sex: All
Age: 18+
Code: NCT07807956
Phase 1, Recruiting
CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors