Frontotemporal Dementia Clinical Trials

Find clinical trials for frontotemporal dementia. Search for frontotemporal dementia clinical trials in different cities and states across the United States.

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Results: 31

LemborexantLemborexant for Insomnia in a Patient With Dementia: An N-of-1 Trial

Recruiting

Sponsor:

Nova Scotia Health Authority

Location:

Halifax

Code:

NCT06093126

Conditions

Insomnia

Dementia

Frontotemporal Dementia

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Not accepted

Interventions

Lemborexant 5 MG

Olipudase AlfaA Real-world Long-term Safety and Immunogenicity Study of Olipudase Alfa Therapy in Pediatric Patients Less Than 2 Years of Age With Acid Sphingomyelinase Deficiency (ASMD)

Recruiting

Sponsor:

Sanofi

Location:

Chicago IL, Cincinnati OH, Columbus OH, Philadelphia PA

Code:

NCT06192576

Conditions

Niemann-Pick Diseases

Acid Sphingomyelinase Deficiency

Eligibility Criteria

Sex: All

Age: 0 - 2

Healthy Volunteers: Not accepted

Interventions

Olipudase alfa

PropranololPropranolol in Primary Progressive Aphasia

Recruiting

EARLY_PHASE1

Sponsor:

University of Missouri-Columbia

Location:

Columbia MO

Code:

NCT06066710

Conditions

Aphasia, Primary Progressive

Eligibility Criteria

Sex: All

Age: 50+

Healthy Volunteers: Not accepted

Interventions

Propranolol

Magnetic Resonance Imaging (MRI)

Placebo

Alzheimer's DiagnosisDiagnosis of Alzheimer's Disease Using Event Related Potentials

Recruiting

Sponsor:

VA Boston Healthcare System

Location:

Jamaica Plain MA

Code:

NCT02957227

Conditions

Mild Cognitive Impairment

Eligibility Criteria

Sex: All

Age: 50 - 70+

Healthy Volunteers: Not accepted

Interventions

No intervention is part of this study but patients use an EEG device during observational data collection.

PBFT02A Study of PBFT02 in Participants With FTD and Mutations in the Granulin Precursor (GRN) or C9ORF72 Genes

Recruiting

PHASE1

PHASE2

Sponsor:

Passage Bio, Inc.

Location:

Philadelphia PA, Houston TX, Toronto, Montreal

Code:

NCT04747431

Conditions

Frontotemporal Dementia

FTD

FTD-GRN

Dementia Frontotemporal

C9orf72

Eligibility Criteria

Sex: All

Age: 35 - 70+

Healthy Volunteers: Not accepted

Interventions

PBFT02

LY3884963Phase 1/2 Clinical Trial of LY3884963 in Patients With Frontotemporal Dementia With Progranulin Mutations (FTD-GRN)

Recruiting

PHASE1

PHASE2

Sponsor:

Prevail Therapeutics

Location:

Maitland FL, Orlando FL, Philadelphia PA

Code:

NCT04408625

Conditions

Frontotemporal Dementia

Eligibility Criteria

Sex: All

Age: 30 - 70+

Healthy Volunteers: Not accepted

Interventions

LY3884963

Methylprednisolone

Optional Sirolimus

Optional Prednisone

DBSSubgenual Cingulate Deep Brain STIMulation for Apathetic Behavioral Variant FRONtotemporal Dementia

Recruiting

Sponsor:

University Health Network, Toronto

Location:

Toronto

Code:

NCT05699330

Conditions

Frontotemporal Dementia

Deep Brain Stimulation

Eligibility Criteria

Sex: All

Age: 40 - 70+

Healthy Volunteers: Not accepted

Interventions

Bilateral subgenual cingulate deep brain stimulation (SGC DBS)

Observational StudyA Multi-Modal Remote Monitoring Platform for Frontotemporal Lobar Degeneration (FTLD) Syndromes

Recruiting

Sponsor:

Massachusetts General Hospital

Location:

Baltimore MD, Boston MA

Code:

NCT05956834

Conditions

PSP

CBD

Progressive Supranuclear Palsy

FTD

Corticobasal Degeneration

Eligibility Criteria

Sex: All

Age: 40 - 70+

Healthy Volunteers: Not accepted

Interventions

PAMSys

LEGSys

Observational StudyRare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

Recruiting

Sponsor:

Sanford Health

Location:

Sioux Falls SD

Code:

NCT01793168

Conditions

Rare Disorders

Undiagnosed Disorders

Disorders of Unknown Prevalence

Cornelia De Lange Syndrome

Prenatal Benign Hypophosphatasia

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Not accepted

Observational StudyLanguage in Primary Progressive Aphasia

Recruiting

Sponsor:

Northwestern University

Location:

Chicago IL

Code:

NCT00537004

Conditions

Primary Progressive Aphasia

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Not accepted