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Gastrointestinal Clinical Trials

Browse 1,492 gastrointestinal clinical trials enrolling across the United States and Canada. 173 people applied to gastrointestinal studies last month. Search by city or state to find one near you.

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Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

for
Rectal Cancer
Location: St. John's, Gloucester MA, Beverly MA, Burlington MA,
Sponsor: Canadian Cancer Trials Group

Sex: All

Age: 18+

Code: NCT06205485

Phase 3, Recruiting

Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC

for
Metastatic Colorectal Cancer, Hepatocellular Carcinoma
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06553885

Phase 2, Recruiting

A Study to Investigate ALE.P02 as a Monotherapy or in Combination With Pembrolizumab in Adult Patients With Selected CLDN1+ Solid Tumors

for
Squamous Non-small-cell Lung Cancer,
Location: Hackensack NJ, Fairfax VA, Chicago IL, Scottsdale AZ,
Sponsor: Alentis Therapeutics AG

Sex: All

Age: 18+

Code: NCT06747585

Phase 1, Phase 2, Recruiting

Striated Esophageal Motor Function Modulation in Health and Disease

for
Dysphagia, Esophageal
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: All

Age: 18 - 70+

Code: NCT05708885

Recruiting

Brain Activity and Oxygenation Inflammatory Bowel Disease (IBD) Patients

for
IBD, Maladaptive Behavior Associated With Physical Illness
Location: Calgary
Sponsor: University of Calgary

Sex: All

Age: 18 - 70+

Code: NCT04733456

Recruiting

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Esophageal Impedance and Manometry Measurements and Dysphagia Symptom Scoring

for
Dysphagia, Esophageal
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 18 - 70+

Code: NCT04503785

Recruiting

Molecular Determinants of Response to Preoperative Therapy in Patients With Locally Advanced Colorectal Cancer

for
Colorectal Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT02877056

Recruiting

A Study of VET3-TGI in Patients With Solid Tumors

for
Solid Tumor, Adult, Microsatellite Stable Colorectal Cancer,
Location: Miami FL, Pittsburgh PA, Indianapolis IN, Houston TX,
Sponsor: KaliVir Immunotherapeutics

Sex: All

Age: 18+

Code: NCT06444815

Phase 1, Recruiting

Eosinophilic Gastrointestinal Disorders Registry

for
Eosinophilic Esophagitis, Eosinophilic Gastroenteritis,
Location: Chicago IL
Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All

Age: 1 - 25

Code: NCT05199532

Recruiting

A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants

for
Crohns Disease, Colitis, Ulcerative, Arthritis, Psoriatic,
Location: Atlanta GA, Cincinnati OH, Indianapolis IN,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 3+

Code: NCT06663332

Phase 3, Recruiting

A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)

for
Advanced Solid Tumor, Metastatic Solid Tumor,
Location: New York NY, Jacksonville FL, Cleveland OH,
Sponsor: GI Innovation, Inc.

Sex: All

Age: 18+

Code: NCT05824975

Phase 1, Phase 2, Recruiting

A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer

for
HER2-positive Gastric Cancer,
Location: Chicoutimi, New York NY, Albany NY, Summit NJ, Montreal,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06764875

Phase 3, Recruiting

Safety and Feasibility Study of the CELLSPAN Esophageal Implant (CEI) in Patients Requiring Short Segment Esophageal Replacement

for
Esophageal Diseases
Location: Ann Arbor MI, Rochester MN, Los Angeles CA
Sponsor: Harvard Apparatus Regenerative Technology, Inc.

Sex: All

Age: 18+

Code: NCT05877300

Phase 1, Recruiting

Early Ileostomy Closure for Rectal Cancer Patients in North America

for
Ileostomy - Stoma, Rectal Cancer
Location: Montreal, London, Vancouver
Sponsor: Jewish General Hospital

Sex: Female

Age: 18 - 70+

Code: NCT05027737

Recruiting

Circulating Tumor DNA Exposure in Peripheral Blood

for
Colorectal Cancer, Pancreatic Adenocarcinoma, Gastric Cancer,
Location: Orlando FL, Celebration FL, Centerville OH, Dayton OH
Sponsor: Quantgene Inc.

Sex: All

Age: 18+

Code: NCT03517332

Recruiting

Testing the Addition of an Anti-Cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (5-Fluorouracil) for Metastatic, Refractory Colorectal Cancer

for
Metastatic Microsatellite Stable Colorectal Carcinoma,
Location: The Bronx NY, Pittsburgh PA, Cincinnati OH,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06654037

Phase 1, Recruiting

The Use of Body Surface Gastric Mapping in Assessing the Clinical Success of G-POEM

for
Gastroparesis
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 18+

Code: NCT06493032

Recruiting

Cap Assisted Colonoscopy for the Detection of Colon Polyps

for
Adenoma, Colon Polyps, Colon Cancer
Location: Kansas City MO
Sponsor: American Society for Gastrointestinal Endoscopy

Sex: All

Age: 21 - 70+

Code: NCT01211132

Recruiting

Evaluating Adrenal Insufficiency in Adults With Eosinophilic Esophagitis on Chronic Swallowed Topical Steroids

for
Eosinophilic Esophagitis
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 18 - 70+

Code: NCT05246085

Recruiting

Identification Genetic, Immunologic and Microbial Markers of Hirschsprung Associated Enterocolitis in Children With Hirschsprung Disease

for
Hirschsprung Disease, Enterocolitis
Location: Los Angeles CA
Sponsor: Cedars-Sinai Medical Center

Sex: All

Age: 0 - 17

Code: NCT02193685

Recruiting