A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions and Subcutaneous Injections of ABBV-519 in Adult Participants With Systemic Lupus Erythematosus (SLE) or Rheumatoid Arthritis (RA)
Interested in new trials?
Get alerts for new trials in your area by subscribing now
Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to Severe Rheumatoid Arthritis Who Have Not Responded to or Who Cannot Tolerate Tumor Necrosis Factor (TNF) and/or Janus Kinase (JAK Inhibitors)
A Dose Response Study to Evaluate the Efficacy and Safety of Oral AP1189 Administered in Disease-Modifying Anti-Rheumatic Drug (DMARD) naïve Participants Participants With Early Rheumatoid Arthritis
A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With Uncontrolled Gout
A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders
What are Gout clinical trials?
Gout clinical trials test different approaches to managing flare-ups, lowering uric acid levels, and preventing long-term joint damage caused by uric acid crystals forming in a joint. Since gout tends to come and go in flares rather than stay constant, researchers have to design studies carefully to capture both sudden flare episodes and longer-term patterns.
The importance of clinical trials in Gout research
Gout is one of the most common forms of inflammatory arthritis, and its flare-ups can look different from person to person. Gout research studies give researchers a consistent way to see what genuinely helps across many people, rather than relying on how any one person happened to respond.
This research also matters because gout is closely connected to other health conditions, like kidney function and metabolic health, so findings from gout studies often contribute to a broader understanding of overall health beyond the joints alone.
Who can participate in Gout clinical trials?
Most gout clinical trials look for adults who've had at least one confirmed gout flare, though some studies focus specifically on people who experience frequent flare-ups or have elevated uric acid levels even between episodes. Others may include people with related conditions, like kidney disease, since the two often overlap.
Typical screening includes blood tests to check uric acid levels, a review of flare history, and sometimes joint fluid or imaging tests to confirm a gout diagnosis. Depending on the study, people with well-managed gout or no gout at all may also be included for comparison.
What to expect when joining a Gout clinical trial?
Enrollment usually starts with blood work and a review of past flare-ups to confirm eligibility and understand how active the condition currently is. From there, the research team provides informed consent, walking through what the study involves and any risks or benefits to consider.
Once enrolled, participants might take a medication or placebo aimed at managing uric acid levels or flare symptoms, with regular blood tests and check-ins scheduled to track how joint symptoms and uric acid levels change throughout the study.
Worried about the risks of participating in a clinical trial? Delve into our comprehensive guide to gain insights into the potential outcomes of participating. Learn about potential risks, benefits, and safety considerations to make an informed decision about your participation in a clinical trial.
Types of Gout clinical trials
Gout research generally splits into two connected goals: managing sudden flare-ups when they happen, and lowering uric acid levels over the long term to prevent them from happening again. Because gout is also closely tied to conditions like kidney disease and heart health, a good amount of research looks at those connections too.
Urate-lowering medication trials
Urate-lowering medication trials test drugs like allopurinol and febuxostat, often comparing them directly to see which one lowers uric acid more effectively or safely over time. Participants typically include adults with a confirmed gout diagnosis and elevated uric acid levels, and studies track blood uric acid levels alongside flare frequency over several months.
Flare prevention and management trials
These trials focus on what happens during and immediately after a flare, testing medications like colchicine to help prevent flares as someone starts a uric acid-lowering medication regimen. Participants usually include people currently experiencing flares or beginning that kind of regimen, and research tracks flare frequency, pain levels, and recovery time.
Comorbidity-focused trials
These trials study gout alongside related health conditions, such as chronic kidney disease or cardiovascular disease, since urate-lowering medications can affect, and be affected by, how well the kidneys or heart are functioning. Participants often include people managing gout together with one of these related conditions, and research tracks both joint symptoms and the related condition side by side.
How to enroll in a clinical trial for Gout
Enrolling in a Gout clinical trial through our platform is a straightforward and user-friendly process. Here's how to get started:
- Identify Your Trial: Use our intuitive search bar or filter options to locate gout clinical trials near you. This first step simplifies the process of finding relevant research studies tailored to you.
- Select Your Preferred Location: To find trials conveniently located near you, simply input your preferred location into the dedicated filter bar on the left-hand side of the page.
- Explore Study Details: For in-depth information about each study, simply click the "Learn More" button. This will provide you with comprehensive details about the trial, including objectives, procedures, and eligibility criteria.
- Complete the Health Profile: After clicking on the "Get started" button you will be taken to our efficient 5-step application process to provide important health information. This helps us match you with the clinical trial that best fits your needs.
- Submit the Application: After completing the application, send it in. A clinical trial coordinator will review it and contact you regarding the possibility of participation.