Browse 73 mantle cell lymphoma clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.
Mantle cell lymphoma is an uncommon lymphoma that often comes back after treatment, which is why remission rather than cure has long been the goal. Over the past decade, targeted pills and CAR T cell therapy have changed what treatment looks like, and many people now live much longer than before. Some forms grow slowly and can be watched, while others need treatment right away. Trials are testing chemotherapy free combinations and newer immune therapies aimed at keeping the lymphoma away for good.
A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.
for
Triple Negative Breast Cancer, Diffuse Large B Cell Lymphoma,
Location: Fairfax VA, Pittsburgh PA, Canton OH, Columbus OH,
Sponsor: OncoNano Medicine, Inc.
Sex: All
Age: 18+
Code: NCT06022029
Phase 1, Recruiting
Feasibility and Safety of Collecting and Combining Autologous Hematopoietic Stem Cells With Chimeric Antigen Receptor (CAR) T-Cell Therapy in Subjects With Relapsed/Refractory Hematological Malignancies
for
Hematologic Malignancy, Large B-cell Lymphoma,
Location: Los Angeles CA
Sponsor: Joshua Sasine, MD, PhD
Sex: All
Age: 18 - 70+
Code: NCT05887167
Phase 1, Recruiting
A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies
for
Chronic Lymphocytic Leukemia (CLL),
Location: New Haven CT, Philadelphia PA, Bethesda MD, Durham NC,
Sponsor: Nurix Therapeutics, Inc.
Sex: All
Age: 18+
Code: NCT05131022
Phase 1, Recruiting
Evaluation of Hypertension Management and Cardiovascular Adverse Event Prevention in Patients With B-cell Malignancies Undergoing Treatment With Bruton Tyrosine Kinase Inhibitors, the HALT Study
for
Chronic Lymphocytic Leukemia,
Location: Rochester MN
Sponsor: Mayo Clinic
Sex: All
Age: 0+
Code: NCT06151730
Recruiting
Acalabrutinib, Obinutuzumab, and Glofitamab for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma
for
Mantle Cell Lymphoma
Location: Duarte CA
Sponsor: City of Hope Medical Center
Sex: All
Age: 18+
Code: NCT06054776
Phase 2, Recruiting
Interested in new trials?
Get alerts for new trials in your area by subscribing now
Evaluation of Human Immune Responses Vaccination in Patients With Lymphoma
for
Chronic Lymphocytic Leukemia, Diffuse Large B-Cell Lymphoma,
Location: Atlanta GA
Sponsor: Emory University
Sex: All
Age: 18+
Code: NCT03501576
Recruiting
Phase II Study of Pirtobrutinib, Rituximab (PR) in Previously Untreated Low and Intermediate Risk MCL (Mantle Cell Lymphoma) Patients
for
Mantle Cell Lymphoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center
Sex: All
Age: 18+
Code: NCT06263491
Phase 2, Recruiting
Preliminary Assessment of [18F]BL40 in PET/CT Scans
for
Diffuse Large B-cell Lymphoma, Multiple Myeloma,
Location: Vancouver
Sponsor: British Columbia Cancer Agency
Sex: All
Age: 19 - 70+
Code: NCT06224309
Recruiting
Intrathecal Cytarabine and Hydrocortisone for the Early Treatment of ICANS in Patients Undergoing CAR T Therapy for Non Hodgkin Lymphoma
for
Non-hodgkin Lymphoma, Recurrent Diffuse Large B-Cell Lymphoma,
Location: Nashville TN
Sponsor: Vanderbilt-Ingram Cancer Center
Sex: All
Age: 18+
Code: NCT07763210
Phase 2, Recruiting
Rituximab (Rtx) + Tafasitamab in Combination With Allogeneic NK Cells for Treatment of Relapsed/Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)
for
Non Hodgkin Lymphoma, B-cell Non Hodgkin Lymphoma,
Location: Cleveland OH
Sponsor: Paolo Caimi, MD
Sex: All
Age: 18+
Code: NCT07225439
Phase 1, Recruiting
The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas
Location: New York NY, Salt Lake City UT, Duarte CA
Sponsor: City of Hope Medical Center
Sex: All
Age: 18 - 70+
Code: NCT05861050
Phase 1, Phase 2, Recruiting
Testing the Anti-cancer Drug, Glofitamab, in Patients With Mantle Cell Lymphoma (A Type of Blood Cancer) Whose Disease Returned After CAR-T Cell Therapy
Location: Baltimore MD, Charlottesville VA, Pittsburgh PA,
Sponsor: National Cancer Institute (NCI)
Sex: All
Age: 18+
Code: NCT07003295
Phase 2, Recruiting
BRAZAN: A Randomized Phase 2 Study of Bendamustine, Rituximab, Cytarabine (AraC) Induction With Zanubrutinib (BRAZAN) Followed by Zanubrutinib/Rituximab +/- Sonrotoclax Maintenance in Treatment-Naïve Mantle Cell Lymphoma
for
Mantle Cell Lymphoma, Lymphoma
Location: Boston MA, New York NY, St Louis MO
Sponsor: Christine Ryan
Sex: All
Age: 18+
Code: NCT06854003
Phase 2, Recruiting
A Study of APG-3288 in Relapsed/Refractory Blood Cancers
for
Relapsed/Refractory Hematological Malignancies,
Location: East Brunswick NJ, Jacksonville FL, Grand Rapids MI,
Sponsor: Ascentage Pharma Group Inc.
Sex: All
Age: 18+
Code: NCT07424833
Phase 1, Recruiting
Pacritinib in Combination With a BTK Inhibitor for the Treatment of Patients With Relapsed or Refractory Mantle Cell Lymphoma
Sonrotoclax Plus Zanubrutinib in Patients With Relapsed/Refractory Mantle Cell Lymphoma Planned for Standard of Care CAR-T Cell Therapy
for
Mantle Cell Lymphoma
Location: Toronto, Hamilton, Edmonton, Calgary, Vancouver
Sponsor: Canadian Cancer Trials Group
Sex: All
Age: 18+
Code: NCT07341191
Phase 2, Recruiting
Zanubrutinib in Combination With Sonrotoclax for the Treatment of Underrepresented Ethnic and Racial Minorities With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma