Browse 73 mantle cell lymphoma clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.
Mantle cell lymphoma is an uncommon lymphoma that often comes back after treatment, which is why remission rather than cure has long been the goal. Over the past decade, targeted pills and CAR T cell therapy have changed what treatment looks like, and many people now live much longer than before. Some forms grow slowly and can be watched, while others need treatment right away. Trials are testing chemotherapy free combinations and newer immune therapies aimed at keeping the lymphoma away for good.
Sonrotoclax, Rituximab, and Zanubrutinib in Treating Participants With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, and Mantle Cell Lymphoma
B-Cell Activating Factor Receptor (BAFFR)-Based Chimeric Antigen Receptor T-Cells With Fludarabine and Cyclophosphamide Lymphodepletion for the Treatment of Relapsed or Refractory B-cell Hematologic Malignancies
for
B-Cell Non-Hodgkin Lymphoma,
Location: Jacksonville FL
Sponsor: Mayo Clinic
Sex: All
Age: 18+
Code: NCT06191887
Phase 1, Recruiting
Local Manufacture of CAR T-Cell Products for the Treatment of B-Cell Lymphoma and B-Acute Lymphoblastic Leukemia
for
B-Cell Lymphoma, B Acute Lymphoblastic Leukemia,
Location: Pittsburgh PA
Sponsor: John Lister
Sex: All
Age: 18 - 70+
Code: NCT05281809
Phase 2, Recruiting
Optimizing ctDNA-based MRD Assessment in DLBCL, MCL, and FL Patients Undergoing CAR Therapy
for
Follicular Lymphoma, Diffuse Large B Cell Lymphoma,
Location: Palo Alto CA
Sponsor: Adaptive Biotechnologies
Sex: All
Age: 18+
Code: NCT05255354
Recruiting
Study of Oral Administration of LP-168 in Patients With Relapsed or Refractory B-cell Malignancies.
Get alerts for new trials in your area by subscribing now
Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma
for
Mantle Cell Lymphoma
Location: Chicago IL, Providence RI, Westerly RI, Waterford CT,
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All
Age: 60+
Code: NCT05976763
Phase 3, Recruiting
Vaccine Responses in Patient With Multiple Myeloma and Non-Hodgkin Lymphoma After CAR-T Treatment
for
Chronic Lymphocytic Leukemia, Diffuse Large B-Cell Lymphoma,
Location: Portland OR
Sponsor: OHSU Knight Cancer Institute
Sex: All
Age: 18+
Code: NCT06784167
Recruiting
DALY II USA/ MB-CART2019.1 for DLBCL
for
Refractory Diffuse Large B Cell Lymphoma (DLBCL),
Location: Boston MA, New Haven CT, New York NY, Baltimore MD,
Sponsor: Miltenyi Biomedicine GmbH
Sex: All
Age: 18+
Code: NCT04792489
Phase 2, Recruiting
Phase 2 Study of BTKi-Rituximab Induction Followed by Glofitamab Consolidation in High Risk Untreated MCL Patients - WINDOW-4 Study
for
Phase 2 Study, MCL, BTKi, Rituximab, Glofitamab
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center
Sex: All
Age: 18+
Code: NCT07257055
Phase 2, Recruiting
A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma
for
Lymphoma
Location: New Haven CT, Stony Brook NY, New Brunswick NJ,
Sponsor: Hoffmann-La Roche
Sex: All
Age: 18+
Code: NCT06084936
Phase 3, Recruiting
(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis
for
Advanced Systemic Mastocytosis (AdvSM),
Location: Boston MA, Charleston SC, Toronto, Atlanta GA,
Sponsor: Cogent Biosciences, Inc.
Sex: All
Age: 18+
Code: NCT04996875
Phase 2, Recruiting
Zanubrutinib and Tafasitamab in Mantle Cell Lymphoma
for
Mantle Cell Lymphoma
Location: Miami FL
Sponsor: Alvaro Alencar, MD
Sex: All
Age: 18+
Code: NCT06029309
Phase 1, Phase 2, Recruiting
Study of Kappa Chimeric Antigen Receptor (CAR) T Lymphocytes Co-Expressing the Kappa and CD28 CARs for Relapsed/Refractory Kappa+ Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.
for
Mantle Cell Lymphoma, Follicular Lymphoma,
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center