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Ophthalmology Clinical Trials

Browse 805 Ophthalmology clinical trials enrolling across the United States and Canada. 112 people applied to Ophthalmology studies last month. Search by city or state to find one near you.

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Observational Trial of the Updated Inserter for the Travoprost Intracameral Implant 75mcg

for
Open Angle Glaucoma (OAG), Ocular Hypertension (OH)
Location: Kenosha WI
Sponsor: Glaukos Corporation

Sex: All

Age: 18+

Code: NCT07400926

Recruiting

Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication Use

for
Glaucoma, Open-Angle Glaucoma, Ocular Hypertension,
Location: Miami FL
Sponsor: University of Miami

Sex: All

Age: 18+

Code: NCT07217678

Recruiting

Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD

for
Geographic Atrophy (GA),
Location: Waterford CT, Springfield MA, Westbury NY, Oceanside NY,
Sponsor: ONL Therapeutics

Sex: All

Age: 55+

Code: NCT06659445

Phase 2, Recruiting

A Safety and Efficacy Study of a One-time Intravitreal Injection of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration

for
Geographic Atrophy
Location: Bethlehem PA, Towson MD, Chevy Chase MD, Hagerstown MD,
Sponsor: Sanofi

Sex: All

Age: 60+

Code: NCT07215234

Phase 1, Phase 2, Recruiting

Randomized Single Center Study to Evaluate Tolerability, Symptoms, and Visual Functional Outcomes With the Use of OTC Lubricating Eye Drops in Subjects With Dry Eye Disease

for
Dry Eye Disease (DED)
Location: Andover MA
Sponsor: Andover Research Eye Institute

Sex: All

Age: 18+

Code: NCT07676084

Recruiting

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An Exploratory Efficacy and Safety Study of DFL24498 Topical Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease

for
Dry Eye Disease (DED)
Location: Garner NC, Lynchburg VA, Cranberry Township PA,
Sponsor: Dompé Farmaceutici S.p.A

Sex: All

Age: 18+

Code: NCT07503886

Phase 2, Recruiting

Phase 1b/2a Study of EYC-0305 in Patients With Neovascular Age-related Macular Degeneration

for
Neovascular (Wet) Age-Related Macular Degeneration
Location: Wake Forest NC, Erie PA, The Woodlands TX, Bellaire TX,
Sponsor: Eyconis INC.

Sex: All

Age: 50+

Code: NCT07587515

Phase 1, Phase 2, Recruiting

A Study to Investigate the Efficacy and Safety of Rilzabrutinib in Adult Participants With Graves' Disease

for
Graves' Disease
Location: Sherbrooke, Calgary, Surrey
Sponsor: Sanofi

Sex: All

Age: 18 - 70+

Code: NCT06984627

Phase 2, Recruiting

Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research

for
Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis,
Location: Delafield WI
Sponsor: Brain Inflammation Collaborative

Sex: All

Age: 2+

Code: NCT04806620

Recruiting

Phase 2 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant

for
Glaucoma
Location: Oklahoma City OK, El Paso TX, Grand Junction CO
Sponsor: Glaukos Corporation

Sex: All

Age: 18+

Code: NCT07075718

Phase 2, Recruiting

Developing Evidence-Based Cognitive Approaches to Improve Adjustment to Vision Loss

for
Depression, Anxiety, Visual Impairment, Adjustment,
Location: Chicago IL
Sponsor: The Chicago Lighthouse

Sex: All

Age: 18+

Code: NCT07073521

Recruiting

A Clinical Trial to Explore the Safety and Efficacy of Injections of Macugen When Given Every 6 Weeks in Subjects With AMD

for
Age-Related Macular Degeneration (AMD)
Location: Abilene TX
Sponsor: Eyetech Pharmaceuticals

Sex: All

Age: 50+

Code: NCT00354445

Recruiting

Safety and Tolerability of RPE Stem Cell-derived RPE(RPESC-RPE) Transplantation in Patients With Dry Age-related Macular Degeneration (AMD)

for
Dry Age-related Macular Degeneration
Location: Ann Arbor MI, Beverly Hills CA, Palo Alto CA
Sponsor: Luxa Biotechnology, LLC

Sex: All

Age: 55+

Code: NCT04627428

Phase 1, Phase 2, Recruiting

Assessment of the Initial Efficacy and Safety of BRM424 Ophthalmic Solutions in Patients With Neurotrophic Keratitis

for
Neurotrophic Keratitis
Location: Leland NC
Sponsor: BRIM Biotechnology Inc.

Sex: All

Age: 18+

Code: NCT05927428

Phase 2, Recruiting

A Study to Evaluate the Safety and Efficacy of NEXAGON® (Lufepirsen Ophthalmic Gel) in Subjects With PCED

for
Persistent Corneal Epithelial Defect
Location: Palisades Park NJ, Bala-Cynwyd PA, South Miami FL,
Sponsor: Glaukos Corporation

Sex: All

Age: 2+

Code: NCT05966493

Phase 2, Recruiting

Comparison of the Alpha-2 Agonists for Prevention of Intraocular Pressure Elevation After Selective Laser Trabeculoplasty

for
Glaucoma, Ocular Hypertension
Location: Washington DC
Sponsor: Walter Reed Army Medical Center

Sex: All

Age: 18+

Code: NCT00567411

Recruiting

Survey Study and Records Review of Treatment Outcomes in Freeman-Sheldon Syndrome

for
Freeman-Burian Syndrome, Freeman-Sheldon Syndrome,
Location: Fairfax VA
Sponsor: Dufresne, Craig, MD, PC

Sex: All

Age: 0+

Code: NCT05419245

Recruiting

Subconjunctival Injection of Local Anesthetic in Anterior Blepharoptosis Repair

for
Blepharoptosis, Ptosis
Location: Winnipeg
Sponsor: University of Manitoba

Sex: All

Age: 18+

Code: NCT02959697

Recruiting

Ozurdex With Rescue Lucentis for Treating Macular Edema Secondary to Retinal Vein Occlusion

for
Retinal Vein Occlusion
Location: Philadelphia PA
Sponsor: Brian Burke, MPH

Sex: All

Age: 18 - 70+

Code: NCT01581151

Recruiting

Study of Treatment Effects of Combination Therapy of Lucentis Plus Reduced Fluence PDT With Visudyne in Patients With Exudative AMD

for
Age-Related Macular Degeneration
Location: St. Louis MO
Sponsor: Barnes Retina Institute

Sex: All

Age: 50+

Code: NCT00455871

Recruiting

What are ophthalmology clinical trials?

Ophthalmology clinical trials are research studies designed to evaluate new treatments, therapies, or diagnostic methods for eye diseases and conditions. These trials focus on a wide range of ophthalmic issues, including but not limited to glaucoma, age-related macular degeneration (AMD), diabetic retinopathy, cataracts, and retinal diseases. Clinical trials in ophthalmology may test new medications, surgical techniques, laser treatments, or medical devices to improve vision, prevent blindness, or manage symptoms of eye diseases.

The data collected from these trials helps advance understanding and development of better treatment options, ultimately aiming to enhance eye health and visual outcomes for patients.

Why are clinical trials for ophthalmology important?

With a vast range of eye conditions and diseases falling under the ophthalmology umbrella, clinical research in this area is highly important. Ophthalmology clinical trials are crucial for driving the development of new and more effective treatments for eye diseases and conditions, which can significantly impact vision and quality of life.

Clinical trials for ophthalmology help researchers to evaluate novel medications, surgical techniques, and diagnostic tools, potentially leading to breakthroughs in managing or curing a range of conditions. Ophthalmology clinical trials play a key role in reducing the burden of visual impairment and blindness, enhancing eye health, and promoting better visual outcomes for future patients.

What types of clinical trials are used for ophthalmology?

Participation in an ophthalmology clinical trial

Who can participate in a clinical trial for ophthalmology?

How to enroll in a ophthalmology clinical trial