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Small Cell Lung Cancer Clinical Trials

Browse 642 small cell lung cancer clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Active & Responsive

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

for
Solid Tumor, Adult, Colorectal Cancer,
Location: New York NY, Jacksonville FL, Tampa FL, Columbus OH,
Sponsor: A2 Biotherapeutics Inc.

Sex: All

Age: 18+

Code: NCT04981119

Recruiting
Active & Responsive

First-In-Human Study of STX-721/PFL-721 in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring EGFR or HER2 Exon 20 Insertion Mutations

for
Non-Small Cell Lung Cancer, NSCLC,
Location: Philadelphia PA, Fairfax VA, Charlotte NC, Nashville TN,
Sponsor: Pierre Fabre Medicament

Sex: All

Age: 18+

Code: NCT06043817

Phase1, Phase2, Recruiting
Active & Responsive

A Phase 1/2 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors

for
Metastatic Hepatocellular Carcinoma,
Location: New York NY, Pittsburgh PA, Birmingham AL, Nashville TN,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT06427941

Phase1, Phase2, Recruiting
Active & Responsive

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

for
Solid Tumor, Adult, Colorectal Cancer, NSCLC,
Location: New York NY, Jacksonville FL, Tampa FL, Columbus OH,
Sponsor: A2 Biotherapeutics Inc.

Sex: All

Age: 18+

Code: NCT06051695

Phase1, Phase2, Recruiting
Active & Responsive

Early Rebiopsy to Identify Biomarkers of Tumor Cell Survival Following EGFR, ALK, ROS1 or BRAF TKI Therapy

for
Non-Small Cell Carcinoma of Lung, TNM Stage 4,
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 18 - 70+

Code: NCT03042221

Recruiting

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Active & Responsive

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

for
NSCLC Adenocarcinoma, Gastroesophageal Cancer (GC),
Location: New York NY, East Brunswick NJ, Philadelphia PA,
Sponsor: IDEAYA Biosciences

Sex: All

Age: 18+

Code: NCT07277413

Phase1, Recruiting
Active & Responsive

LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC

for
Metastatic Non-small Cell Lung Cancer
Location: Shirley NY, New Hyde Park NY, The Bronx NY, New York NY,
Sponsor: NovoCure GmbH

Sex: All

Age: 18+

Code: NCT06216301

Phase3, Recruiting
Active & Responsive

Safety and Preliminary Efficacy of Pumitamig (BNT327), an Investigational Therapy for Patients With Non-small Cell Lung Cancer in Combination With Chemotherapy as First-line or Second-line Treatment

for
Non-small Cell Lung Cancer
Location: New York NY, Tampa FL, Elizabethtown KY, Birmingham AL
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT06841055

Phase2, Recruiting
Active & Responsive

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors, Genital Neoplasm, Female,
Location: Boston MA, Bethesda MD, Toronto, Celebration FL,
Sponsor: Marengo Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05592626

Phase1, Phase2, Recruiting
Active & Responsive

Efficacy & Safety of Olvimulogene Nanivacirepvec & Platinum-doublet + Physician's Choice of Immune Checkpoint Inhibitor Compared to Docetaxel in NSCL Cancer

for
Advanced Non-squamous Non-small-cell Lung Cancer,
Location: Mullica Hill NJ, Miami FL, Plantation FL,
Sponsor: Genelux Corporation

Sex: All

Age: 18+

Code: NCT06463665

Phase2, Recruiting
Active & Responsive

Safety Trial of Antimicrobial Therapy and Precision Radiation Therapy in Patients With Oligoprogressive Non-small Cell Lung Cancer

for
Early Stage Non-Small Cell Lung Cancer
Location: Philadelphia PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All

Age: 18+

Code: NCT03546829

Phase1, Recruiting
Active & Responsive

Clinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer

for
Non-Small Cell Lung Cancer
Location: Baltimore MD, Fairfax VA, Columbus OH, Lexington KY,
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT05142189

Phase1, Recruiting
Active & Responsive

Phase 1 Study Of Izalontamab Brengitecan + Adagrasib In NSCLC - The IZA-A Trial

for
Non-small Cell Lung Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07382726

Phase1, Recruiting
Active & Responsive

First-Line Ipilimumab Plus Nivolumab and Nogapendekin Alfa Inbakicept (N-803) in Patients With Stage IV or Recurrent Non-Small Cell Lung Cancer

for
Non-small Cell Lung Cancer Stage IV,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT07355205

Phase1, Phase2, Recruiting
Active & Responsive

A Study To Assess the Safety, Tolerability, and Efficacy of Imzokitug in Combination With Pumitamig and Platinum-Doublet Chemotherapy (PDCT) Versus Pumitamig and PDCT as First-line Treatment for Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

for
Locally Advanced Non-Small Cell Lung Cancer (NSCLC),
Location: Omaha NE, Grand Island NE
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07680764

Phase2, Recruiting
Active & Responsive

TCR1188-ABC Cells in KRAS-mutated Cancers

for
Cholangiocarcinoma, Colorectal Cancer,
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: All

Age: 18+

Code: NCT07594067

Phase1, Recruiting
Active & Responsive

The EASE Study: Randomized Trial of a Novel Approach to Addressing Fear of Progression in Advanced Cancer

for
Advanced Solid Tumor Cancer,
Location: Aurora CO, Boulder CO
Sponsor: University of Colorado, Boulder

Sex: All

Age: 18+

Code: NCT07636200

Recruiting
Active & Responsive

A Clinical Trial of Calderasib (MK-1084) and Durvalumab in People With Non-Small Cell Lung Cancer (MK-1084-015/KANDLELIT-015)

for
Non-small Cell Lung Cancer
Location: Albany NY, Fairfax VA, Raleigh NC, Lincoln NE
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07554339

Phase3, Recruiting
Active & Responsive

A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014)

for
Non-small Cell Lung Cancer
Location: New Haven CT, White Plains NY, Albany NY, Montreal,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07513376

Phase3, Recruiting
Active & Responsive

Risk-adapted, Proteomic-guided Systemic Therapy for Previously Untreated Advanced Non-small Cell Lung Cancer

for
Non-small Cell Lung Cancer Stage IIIC,
Location: Truckee CA, Chico CA, Marysville CA, Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT07250477

Phase2, Recruiting