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Paid Clinical Trials Costa Mesa

Discover 3,599 paid clinical trials in Costa Mesa, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Featured

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for
Moderately to Severely Active Crohns Disease
Location: Newport Beach CA, Santa Clarita CA, Lancaster CA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 16 - 70+

Code: NCT06819891

Phase 3, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer
Location: Newport Beach CA, Irvine CA, Orange CA, Los Angeles CA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06793215

Phase 3, Recruiting
Featured

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

for
Obesity or Overweight
Location: Irvine CA, San Diego CA, Walnut Creek CA, Tucson AZ,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07351045

Phase 3, Recruiting
Featured

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

for
Obesity or Overweight, Type 2 Diabetes Mellitus
Location: Irvine CA, Lake Forest CA, Long Beach CA, Norco CA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07351058

Phase 3, Recruiting
Featured

A Study Evaluating Adherence, Tolerability, and Patient Reported Outcomes of Giredestrant in Participants With ER+/HER2- Early Breast Cancer Who Are Intolerant to Adjuvant Aromatase Inhibitor Therapy (novERA Breast Cancer)

for
Early Breast Cancer
Location: Fountain Valley CA, Stockton CA, Reno NV,
Sponsor: Genentech, Inc.

Sex: Female

Age: 18+

Code: NCT07541079

Phase 3, Recruiting

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Featured

A Study to Assess the Safety and Effects of ABBV-1758 Following Subcutaneous or Intravenous Injections in Participants With Alzheimer's Disease

for
Alzheimer's Disease
Location: Irvine CA, Boulder CO, Dallas TX, Cordova TN,
Sponsor: AbbVie

Sex: All

Age: 50 - 70+

Code: NCT07599670

Phase 1, Phase 2, Recruiting
Featured

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

for
Alzheimers Disease
Location: Irvine CA, Santa Ana CA, Long Beach CA, Los Angeles CA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 50 - 70+

Code: NCT07177352

Phase 3, Recruiting
Featured

A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants With Severe Alopecia Areata

for
Alopecia Areata
Location: Fountain Valley CA, Los Angeles CA, Thousand Oaks CA,
Sponsor: AbbVie

Sex: All

Age: 12 - 63

Code: NCT06012240

Phase 3, Recruiting
Featured

A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

for
Non Small Cell Lung Cancer, c-MET
Location: Huntington Beach CA, Irvine CA, Duarte CA, Lancaster CA,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT04928846

Phase 3, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

for
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis,
Location: Fountain Valley CA, Orange CA, Long Beach CA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18 - 70+

Code: NCT06318169

Phase 3, Recruiting
Featured

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

for
Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis,
Location: Fountain Valley CA, Los Angeles CA, Pasadena CA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18 - 70+

Code: NCT06419374

Phase 3, Recruiting
Featured

A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions and Subcutaneous Injections of ABBV-519 in Adult Participants With Systemic Lupus Erythematosus (SLE) or Rheumatoid Arthritis (RA)

for
Systemic Lupus Erythematosus, Rheumatoid Arthritis
Location: Tustin CA, Red Oak TX, Houston TX, Jackson TN,
Sponsor: AbbVie

Sex: All

Age: 18 - 70+

Code: NCT07607964

Phase 1, Recruiting
Featured

A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events

for
Atherosclerosis
Location: Irvine CA, Beverly Hills CA, Los Angeles CA,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT07448038

Phase 2, Recruiting
Featured

A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

for
Epithelial Ovarian Cancer, Fallopian Tube Cancer,
Location: Irvine CA, Los Angeles CA, San Diego CA,
Sponsor: AbbVie

Sex: Female

Age: 18+

Code: NCT06890338

Phase 2, Recruiting
Featured

A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophilia A

for
Hemophilia A
Location: Orange CA, Aurora CO, Seattle WA, San Antonio TX,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 12+

Code: NCT07416604

Phase 3, Recruiting
Featured

A Gene Therapy Study of SPK-8011QQ in Adults With Severe or Moderately Severe Hemophilia A

for
Hemophilia A
Location: Orange CA, San Francisco CA, Vallejo CA, Newark NJ,
Sponsor: Hoffmann-La Roche

Sex: Male

Age: 18+

Code: NCT07226206

Phase 1, Phase 2, Recruiting
Featured

A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated Breast Cancer

for
Breast Cancer
Location: Orange CA, Los Angeles CA, Vancouver, Austin TX,
Sponsor: Hoffmann-La Roche

Sex: Female

Age: 18+

Code: NCT07054190

Phase 2, Recruiting
Featured

A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)

for
Non-small Cell Lung Cancer
Location: Orange CA, Los Angeles CA, Sacramento CA, Houston TX,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT04302025

Phase 2, Recruiting
Featured

A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.

for
Depression, Bipolar I Disorder
Location: Orange CA, Anaheim CA, Long Beach CA, Chino CA,
Sponsor: AbbVie

Sex: All

Age: 10 - 17

Code: NCT04777357

Phase 3, Recruiting
Featured

A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)

for
Hepatocellular Cancer, Squamous-Cell Non-Small Cell Lung Cancer
Location: Orange CA, Irvine CA, Los Angeles CA, Duarte CA,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06858813

Phase 1, Recruiting