Discover 3,599 paid clinical trials in Costa Mesa, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
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Featured
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer
for
Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer,
Location: Irvine CA, Santa Monica CA, Duarte CA, Stanford CA,
Sponsor: Hoffmann-La Roche
Sex: Female
Age: 18+
Code: NCT04802759
Phase 1, Phase 2, Recruiting
Featured
A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer
for
Metastatic Breast Cancer
Location: Irvine CA, Corona CA, Duarte CA, Los Angeles CA,
Sponsor: Hoffmann-La Roche
Sex: All
Age: 18+
Code: NCT05894239
Phase 3, Recruiting
Featured
A Study to Assess Adverse Events, Change in Disease Activity and How Intravenous (IV) ABBV901 Moves Through the Body Alone or in Combination With Other Anticancer Drugs in Adult Participants With Ovarian Cancer
for
Ovarian Cancer
Location: Irvine CA, Duarte CA, West Valley City UT, Denver CO,
Sponsor: AbbVie
Sex: All
Age: 18+
Code: NCT07278336
Phase 1, Recruiting
Featured
A Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) Telisotuzumab Adizutecan, Monotherapy or in Combination With Osimertinib, Compared to Standard of Care in Adult Participants With Locally Advanced or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer
for
Non-Small Cell Lung Cancer, c-MET
Location: Irvine CA, Duarte CA, La Jolla CA, Vancouver WA,
Sponsor: AbbVie
Sex: All
Age: 18+
Code: NCT07155187
Phase 2, Phase 3, Recruiting
Featured
A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer
for
Small Cell Lung Cancer
Location: Irvine CA, Duarte CA, Goodyear AZ, Eugene OR,
Sponsor: AbbVie
Sex: All
Age: 18+
Code: NCT07365241
Phase 3, Recruiting
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Featured
Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma
for
Multiple Myeloma
Location: Irvine CA, Duarte CA, Houston TX, Cincinnati OH,
Sponsor: Hoffmann-La Roche
Sex: All
Age: 18+
Code: NCT07555938
Phase 3, Recruiting
Featured
A Study to Evaluate Adverse Events, Change in Disease Activity, Tolerability, and How Intravenous ABBV-438 Moves Through the Body in Adult Participants With Multiple Myeloma (MM)
for
Multiple Myeloma
Location: Irvine CA, Duarte CA, Denver CO, Chicago IL,
Sponsor: AbbVie
Sex: All
Age: 18+
Code: NCT07409246
Phase 1, Recruiting
Featured
A Study to Assess the Adverse Events, Change in Disease Activity, and How Oral ABBV-711 Tablets Move Through the Body as a Monotherapy and in Combination With Intravenously Infused Budigalimab (ABBV-181), in Adults With Advanced Squamous Tumors
for
Advanced Squamous Tumors
Location: Irvine CA, Duarte CA, Irving TX, Chicago IL,
Sponsor: AbbVie
Sex: All
Age: 18+
Code: NCT07241039
Phase 1, Recruiting
Featured
A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving T Cell Engaging Bi/Tri-specific Antibodies Intravenously (IV)/Subcutaneously (SC) Alone or in Combinations
for
Multiple Myeloma
Location: Irvine CA, Duarte CA, San Francisco CA,
Sponsor: AbbVie
Sex: All
Age: 18+
Code: NCT06892522
Phase 1, Phase 2, Recruiting
Featured
A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer
for
Breast Cancer
Location: Irvine CA, Duarte CA, San Diego CA, La Jolla CA,
Sponsor: Genentech, Inc.
Sex: All
Age: 18+
Code: NCT07100106
Phase 1, Phase 2, Recruiting
Featured
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
for
Breast Cancer
Location: Irvine CA, Los Alamitos CA, Long Beach CA,
Sponsor: Hoffmann-La Roche
Sex: All
Age: 18+
Code: NCT06790693
Phase 3, Recruiting
Featured
Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis
for
Crohn's Disease, Ulcerative Colitis
Location: Anaheim CA, Los Alamitos CA, Rialto CA, Lancaster CA,
Sponsor: AbbVie
Sex: All
Age: 18 - 70+
Code: NCT07697456
Phase 2, Recruiting
Featured
Study to Assess the Real-World Effectiveness of Ubrogepant in Adult Participants When Treating During the Prodrome Phase of Migraine Attacks
for
Migraine
Location: Aliso Viejo CA, Grand Island NE, Naperville IL
Sponsor: AbbVie
Sex: All
Age: 18+
Code: NCT07310290
Recruiting
Featured
A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years
for
Chronic Migraine
Location: Anaheim CA, Long Beach CA, Oceanside CA, Fresno CA,
Sponsor: AbbVie
Sex: All
Age: 12 - 17
Code: NCT06810505
Phase 3, Recruiting
Featured
Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)
for
Migraine
Location: Anaheim CA, La Palma CA, Oceanside CA, Winnetka CA,
Sponsor: AbbVie
Sex: All
Age: 6 - 17
Code: NCT05125302
Phase 3, Recruiting
Featured
A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine
for
Episodic Migraine
Location: Anaheim CA, Long Beach CA, San Jose CA, Walnut Creek CA,
Sponsor: AbbVie
Sex: All
Age: 6 - 17
Code: NCT05711394
Phase 3, Recruiting
Featured
A Study to Assess Adverse Events, Change in Disease Activity, and How Oral Emraclidine Moves Through the Body in Adult Participants With Schizophrenia
for
Schizophrenia
Location: Los Alamitos CA, Glendale CA, Austin TX, Richardson TX,
Sponsor: AbbVie
Sex: All
Age: 18 - 65
Code: NCT07145918
Phase 2, Recruiting
Featured
A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus Ribociclib Plus Fulvestrant in Participants With Advanced Breast Cancer
for
Breast Cancer
Location: Anaheim CA, Palo Alto CA, Pierre SD, Mitchell SD,
Sponsor: Hoffmann-La Roche
Sex: All
Age: 18+
Code: NCT07405801
Phase 2, Recruiting
Featured
A Study to Assess Safety, Tolerability, and How Single and Multiple Injections or Infusions of ABBV-313 Affects the Body of Adult Participants
for
Healthy Volunteers
Location: Anaheim CA, Grayslake IL
Sponsor: AbbVie
Sex: All
Age: 18 - 55
Code: NCT07673120
Phase 1, Recruiting
Featured
A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease
for
Colorectal Cancer
Location: Fullerton CA, Los Angeles CA, Portland OR,