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Paid Clinical Trials Costa Mesa

Discover 3,564 paid clinical trials in Costa Mesa, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

for
Carcinoma, Transitional Cell, Urinary Bladder Neoplasms,
Location: Irvine CA, Orange CA, Torrance CA, Los Angeles CA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07218380

Phase3, Recruiting

A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)

for
Accelerated Phase Myeloproliferative Neoplasm,
Location: Irvine CA, Orange CA, Palo Alto CA, Sacramento CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06661915

Phase2, Recruiting

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

for
Endometrial Carcinoma, Endometrial Clear Cell Adenocarcinoma,
Location: Irvine CA, Orange CA, Riverside CA, Los Angeles CA,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT05256225

Phase3, Recruiting

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

for
Metastatic Malignant Solid Neoplasm,
Location: Irvine CA, Orange CA, Duarte CA, Upland CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05372614

Phase1, Recruiting

Testing the Effect of Teclistamab on Recurrent Plasmablastic Lymphoma

for
Recurrent Plasmablastic Lymphoma,
Location: Irvine CA, Orange CA, Los Angeles CA, Duarte CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07332507

Phase1, Recruiting

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Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

for
Astrocytoma, IDH-Mutant, Grade 2,
Location: Irvine CA, Orange CA, Duarte CA, La Jolla CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06860594

Phase1, Recruiting

Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer

for
Astrocytoma, IDH-Mutant, Grade 3
Location: Irvine CA, Orange CA, Duarte CA, Bakersfield CA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 12+

Code: NCT07215910

Phase3, Recruiting

Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

for
Metastatic Castration-Resistant Prostate Carcinoma,
Location: Irvine CA, Orange CA, Los Angeles CA, Bakersfield CA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: Male

Age: 18+

Code: NCT07200830

Phase3, Recruiting

A Study Comparing JNJ-79635322 and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

for
Multiple Myeloma
Location: Irvine CA, Orange CA, Beverly Hills CA, Los Angeles CA,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT07518186

Phase3, Recruiting

Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial

for
Anatomic Stage II Breast Cancer AJCC v8,
Location: Irvine CA, Orange CA, Yorba Linda CA, Beverly Hills CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07391774

Phase3, Recruiting

Testing Whether High Dose Chemotherapy and Infusion of the Patients' Own Stem Cells Improves Survival in Patients With Peripheral T-cell Lymphoma Who Achieved a Complete Response at the End of the Initial Chemotherapy

for
Anaplastic Large Cell Lymphoma, ALK-Negative,
Location: Irvine CA, Orange CA, Duarte CA, Burbank CA, Phoenix AZ,
Sponsor: Eastern Cooperative Oncology Group

Sex: All

Age: 18 - 70+

Code: NCT06724237

Phase3, Recruiting

Testing the Addition of Cemiplimab (REGN2810) to Chemotherapy Treatment Given Prior to Surgery in Patients With Sinonasal Squamous Cell Carcinoma

for
Sinonasal Squamous Cell Carcinoma,
Location: Irvine CA, Orange CA, Los Angeles CA, Sacramento CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07281417

Phase2, Recruiting

Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia

for
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative,
Location: Irvine CA, Orange CA, Duarte CA, La Jolla CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT03739814

Phase2, Recruiting

Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity

for
Gastric Adenocarcinoma,
Location: Irvine CA, Orange CA, Los Angeles CA, Palo Alto CA,
Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All

Age: 18+

Code: NCT07001748

Phase2, Phase3, Recruiting

Testing the Safety of Anti-Cancer Drug, CX-5461 (Pidnarulex), in Treating Lymphoma With Specific Changes in the MYC Gene

for
Burkitt Lymphoma, Double-Expressor Lymphoma,
Location: Irvine CA, Orange CA, Oklahoma City OK,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07069699

Phase1, Phase2, Recruiting

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study

for
Muscle Invasive Bladder Urothelial Carcinoma,
Location: Irvine CA, Orange CA, La Jolla CA, Sacramento CA,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT07097142

Phase3, Recruiting

Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial

for
Advanced Hepatocellular Carcinoma,
Location: Irvine CA, Orange CA, Sunnyvale CA, Mountain View CA,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT07166406

Phase3, Recruiting

Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer

for
Head and Neck Squamous Cell Carcinoma,
Location: Irvine CA, Orange CA, Los Angeles CA, Portland OR,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06980038

Phase2, Recruiting

A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

for
Locally Advanced Urothelial Carcinoma,
Location: Irvine CA, Orange CA, Phoenix AZ, Anaconda MT,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06524544

Phase3, Recruiting

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

for
Non-Small Cell Lung Cancer
Location: Irvine CA, Orange CA, Reno NV, Edwards CO, Portland OR,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07100080

Phase2, Phase3, Recruiting