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Paid Clinical Trials Costa Mesa

Discover 3,605 paid clinical trials in Costa Mesa, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Testing the Safety and Feasibility of Immunotherapy Drugs, Botensilimab and Balstilimab, Before Surgery for Clear Cell Renal Cell Carcinoma, NEO RoBOT Trial

for
Clear Cell Renal Cell Carcinoma,
Location: Irvine CA, Orange CA, Oklahoma City OK, Gainesville FL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07516366

Phase 2, Recruiting

ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Irvine CA, Orange CA, Yorba Linda CA, La Jolla CA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT06876714

Phase 3, Recruiting

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

for
Locally Advanced Cervical Adenocarcinoma,
Location: Irvine CA, Orange CA, Bellflower CA, Harbor City CA,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT07061977

Phase 3, Recruiting

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

for
Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma,
Location: Irvine CA, Orange CA, La Jolla CA, Santa Barbara CA,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT06958328

Phase 3, Recruiting

Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy

for
Recurrent Non-Muscle Invasive Bladder Carcinoma,
Location: Irvine CA, Orange CA, Phoenix AZ, Gilbert AZ, Reno NV,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT07000084

Phase 3, Recruiting

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A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)

for
Endometrial Cancer
Location: Irvine CA, Orange CA, Solvang CA, Walnut Creek CA,
Sponsor: Merck Sharp & Dohme LLC

Sex: Female

Age: 18+

Code: NCT06952504

Phase 3, Recruiting

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

for
Castration-Resistant Prostate Carcinoma,
Location: Irvine CA, Orange CA, Encinitas CA, La Jolla CA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT06632977

Phase 2, Recruiting

Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma

for
Cutaneous Melanoma, Stage II
Location: Irvine CA, Orange CA, Los Angeles CA, Pasadena CA,
Sponsor: Melanoma and Skin Cancer Trials Limited

Sex: All

Age: 18+

Code: NCT03860883

Recruiting

Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma

for
Retroperitoneal Sarcoma, Liposarcoma, Leiomyosarcoma
Location: Irvine CA, Orange CA, Duarte CA, La Jolla CA,
Sponsor: European Organisation for Research and Treatment of Cancer - EORTC

Sex: All

Age: 18+

Code: NCT04031677

Phase 3, Recruiting

Study to Investigate the Efficacy, Safety, and Tolerability of Topical HT-001 for the Treatment of Skin Toxicities Associated With Epidermal Growth Factor Receptor Inhibitors

for
Acneiform Eruption Due to Chemical, Xerosis Cutis, Paronychia
Location: Irvine CA, Orange CA, Houston TX, Canton OH, Miami FL,
Sponsor: Hoth Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05639933

Phase 2, Recruiting

Pembrolizumab Plus CA-4948 for the Treatment of Patients With Progressive Metastatic Urothelial Cancer Despite Prior Immunotherapy

for
Metastatic Urothelial Carcinoma,
Location: Irvine CA, Orange CA, Duarte CA, La Jolla CA, Dallas TX,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06439836

Phase 1, Recruiting

Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma

for
Classic Follicular Lymphoma,
Location: Irvine CA, Orange CA, Long Beach CA, Yorba Linda CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06337318

Phase 3, Recruiting

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

for
Acute Myeloid Leukemia,
Location: Irvine CA, Orange CA, Los Angeles CA, Fresno CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05564390

Phase 2, Recruiting

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

for
Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8,
Location: Irvine CA, Orange CA, Torrance CA, Beverly Hills CA,
Sponsor: NRG Oncology

Sex: Male

Age: 18+

Code: NCT05946213

Phase 3, Recruiting

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

for
Metastatic Renal Cell Carcinoma,
Location: Irvine CA, Orange CA, Los Angeles CA, Beverly Hills CA,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT05327686

Phase 2, Recruiting

Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein β-Catenin, The SAPHIRE Trial

for
Advanced Hepatocellular Carcinoma,
Location: Irvine CA, Orange CA, Portland OR, Pittsburgh PA
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06811116

Phase 1, Phase 2, Recruiting

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial

for
Metastatic Colorectal Adenocarcinoma,
Location: Irvine CA, Orange CA, Beverly Hills CA, Los Angeles CA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT05673148

Phase 2, Recruiting

Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer

for
Refractory Differentiated Thyroid Gland Carcinoma
Location: Irvine CA, Orange CA, Burbank CA, Palo Alto CA, Napa CA,
Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All

Age: 18+

Code: NCT06475989

Phase 3, Recruiting

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

for
Metastatic Castration-resistant Prostate Cancer (mCRPC),
Location: Irvine CA, Orange CA, Riverside CA, Los Angeles CA,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06136650

Phase 3, Recruiting

Endovascular AAA Intervention Using the GORE® EXCLUDER® Conformable AAA Endoprosthesis or Iliac Branch Endoprosthesis

for
AAA - Abdominal Aortic Aneurysm
Location: Irvine CA, Los Angeles CA, Palo Alto CA, Stanford CA,
Sponsor: W.L.Gore & Associates

Sex: All

Age: 18+

Code: NCT06218875

Recruiting