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Paid Clinical Trials Costa Mesa

Discover 3,561 paid clinical trials in Costa Mesa, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)

for
Alzheimer's Disease
Location: Irvine CA, Fullerton CA, Los Angeles CA, Palo Alto CA,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 60 - 70+

Code: NCT06976203

Phase3, Recruiting

A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic Inflammatory Myopathies (Polymyositis and Dermatomyositis)

for
Polymyositis, Dermatomyositis
Location: Irvine CA, El Paso TX, Aurora CO, Colleyville TX,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06455449

Phase3, Recruiting

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

for
Obesity, Overweight, Chronic Weight Management,
Location: Fountain Valley CA, Rolling Hills Estates CA,
Sponsor: Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT07654374

Phase3, Recruiting

Efficacy in Controlling Myopia in Young Children Using a Novel Spectacle Lens

for
Myopia, Juvenile Myopia, Myopia Progression
Location: Santa Ana CA, San Diego CA, Oakland CA,
Sponsor: SightGlass Vision, Inc.

Sex: All

Age: 6 - 8

Code: NCT06034327

Recruiting

Clinical Protocol CERN Feasibility Study

for
Bacterial Vaginosis, Fungal Vaginal Infections
Location: Santa Ana CA, Irvine CA, Orange CA
Sponsor: Cern Corporation

Sex: Female

Age: 18+

Code: NCT06933420

Recruiting

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Real-world Experience on Using Nemolizumab in the Treatment of Moderate-to- Severe Prurigo Nodularis in Adults

for
Prurigo Nodularis
Location: Fountain Valley CA, Corona CA, Santa Monica CA,
Sponsor: Galderma R&D

Sex: All

Age: 18+

Code: NCT06988618

Recruiting

GEMINI-NSCLC: NSCLC Biomarker Study

for
Non-Small Cell Lung Cancer
Location: Fountain Valley CA, Los Angeles CA, Las Vegas NV,
Sponsor: Tempus AI

Sex: All

Age: 18+

Code: NCT05236114

Recruiting

A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma

for
Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung
Location: Fountain Valley CA, Beverly Hills CA, Dallas TX,
Sponsor: Lantern Pharma Inc.

Sex: All

Age: 18+

Code: NCT05456256

Phase2, Recruiting

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

for
Locally Advanced Head and Neck Squamous Cell Carcinoma
Location: Fountain Valley CA, Whittier CA, Los Angeles CA,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06129864

Phase3, Recruiting

Study to Assess the Efficacy and Safety of Rina-S in Participants With Non-small Cell Lung Cancer

for
Non-small Cell Lung Cancer (NSCLC)
Location: Fountain Valley CA, San Diego CA, Santa Rosa CA,
Sponsor: Genmab

Sex: All

Age: 18+

Code: NCT07288177

Phase2, Recruiting

A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

for
Metastatic Castration-Resistant Prostate Cancer
Location: Fountain Valley CA, Laguna Hills CA, Anaheim CA,
Sponsor: Pfizer

Sex: Male

Age: 18+

Code: NCT06629779

Phase3, Recruiting

Development and Analysis of a Stool Bank for Cancer Patients

for
Carcinoma, Non-Small-Cell Lung, Carcinoma, Colorectal
Location: Fountain Valley CA, Winter Haven FL
Sponsor: Persephone Biosciences

Sex: All

Age: 18+

Code: NCT04291755

Recruiting

DPX-Survivac and Pembrolizumab With and Without Intermittent Low-Dose Cyclophosphamide, in Subjects With Relapsed/Refractory Diffuse Large B-Cell Lymphoma

for
Relapsed Diffuse Large B-cell Lymphoma,
Location: Fountain Valley CA, Santa Fe NM, Omaha NE, Saskatoon,
Sponsor: ImmunoVaccine Technologies, Inc. (IMV Inc.)

Sex: All

Age: 18+

Code: NCT04920617

Phase2, Recruiting

A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer

for
Metastatic Non-small Cell Lung Cancer
Location: Fountain Valley CA, La Jolla CA, San Diego CA,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06417814

Phase3, Recruiting

Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

for
Osteoarthritis, Overweight or Obesity
Location: Fountain Valley CA, Santa Ana CA, Spring Valley CA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07353931

Phase3, Recruiting

Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)

for
Type 2 Diabetes, Cortisol Excess
Location: Fountain Valley CA, Long Beach CA, Huntington Park CA,
Sponsor: Sparrow Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07296484

Phase2, Recruiting

A Safety and Immunogenicity Study of CHIKV VLP Vaccine in Children.

for
Chikungunya Virus
Location: Fountain Valley CA, West Jordan UT, Omaha NE,
Sponsor: Bavarian Nordic

Sex: All

Age: 1 - 11

Code: NCT07003984

Phase3, Recruiting

A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

for
Colorectal Neoplasms
Location: Fountain Valley CA, Anaheim CA, Pasadena CA,
Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All

Age: 18+

Code: NCT05253651

Phase3, Recruiting

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

for
Non-Small Cell Lung Cancer
Location: Fountain Valley CA, Anaheim CA, Beverly Hills CA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06357533

Phase3, Recruiting

A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition

for
Metabolic Dysfunction-Associated SteatoHepatitis (MASH)
Location: Fountain Valley CA, Orange CA, Long Beach CA,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT05519475

Phase2, Recruiting