Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Clinical trials in Irvine address a diverse range of conditions, from mental health disorders and neurological diseases to skin conditions and cardiovascular issues. As one of California’s thriving research hubs, the city provides participants with a chance to explore cutting-edge therapies and receive specialized care, all while contributing to the advancement of medical science in their region.
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Results: 3,580
Aveir VR Coverage With Evidence Development Post-Approval Study
for
Cardiac Pacemaker, Arrythmia, Bradycardia
Location: Sylmar CA
Sponsor: Abbott Medical Devices
Sex: All
Age: 18+
Code: NCT05336877
Recruiting
Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint Inhibitor
for
Patients With Non-Small Cell Lung Cancer
Location: Beverly Hills CA, Wheat Ridge CO, Puyallup WA,
Sponsor: OSE Immunotherapeutics
Sex: All
Age: 18+
Code: NCT06472245
Phase3, Recruiting
A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
Location: Santa Monica CA, San Francisco CA, Houston TX,
Sponsor: Bayer
Sex: All
Age: 18+
Code: NCT06452277
Phase3, Recruiting
Neutrophil and Monocyte Deactivation Via the SeLective CytopheretIc Device - A Randomized Clinical Trial in Acute Kidney Injury
for
Acute Kidney Injury
Location: Los Angeles CA, Palo Alto CA, San Francisco CA,
Sponsor: SeaStar Medical
Sex: All
Age: 18+
Code: NCT05758077
Recruiting
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
for
Carcinoma, Non-Small-Cell Lung
Location: Orange CA, Los Angeles CA, Oceanside CA, San Diego CA,
Sponsor: Eli Lilly and Company
Sex: All
Age: 18+
Code: NCT06890598
Phase3, Recruiting
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A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1
for
Neurofibromatosis Type 1
Location: Los Angeles CA, Palo Alto CA, Aurora CO, Dallas TX,
Sponsor: Healx Limited
Sex: All
Age: 12+
Code: NCT06541847
Phase2, Recruiting
Safely Optimizing Body Weight With Mifomelatide (TCMCB07) in Patients With Newly Diagnosed Colorectal Cancer (CRC) or Pancreatic Ductal Adenocarcinoma (PDAC) Undergoing Chemotherapy
for
Cancer Weight Loss
Location: Los Angeles CA, Santa Monica CA, Tucson AZ,
Sponsor: Endevica Bio
Sex: All
Age: 18+
Code: NCT06937177
Phase2, Recruiting
Positive Peers Intervention Clinical Trial
for
HIV Infections
Location: Van Nuys CA, Seattle WA, Houston TX, Memphis TN,
Sponsor: MetroHealth Medical Center
Sex: All
Age: 13 - 34
Code: NCT06388109
Recruiting
A Study of D3S-001 Monotherapy or Combination Therapy in Subjects With Advanced Solid Tumors With a KRAS p.G12C Mutation
for
KRAS P.G12C
Location: Orange CA, Palo Alto CA, Denver CO, Houston TX,
Sponsor: D3 Bio (Wuxi) Co., Ltd
Sex: All
Age: 18+
Code: NCT05410145
Phase1, Phase2, Recruiting
A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer
for
Advanced Breast Cancer
Location: Duarte CA, Santa Monica CA, La Jolla CA, Palo Alto CA,
Sponsor: Stemline Therapeutics, Inc.
Sex: All
Age: 18+
Code: NCT06638307
Phase1, Recruiting
A Long-Term Study of Zasocitinib in Children and Teenagers With Plaque Psoriasis
for
Plaque Psoriasis
Location: Fountain Valley CA, Chula Vista CA, San Antonio TX,
Sponsor: Takeda
Sex: All
Age: 4 - 17
Code: NCT07250802
Phase3, Recruiting
New
A Study to Assess the Efficacy and Safety of GIA632 Across a Range of Doses in Participants With Moderate to Severe Cutaneous Lichen Planus
for
Cutaneous Lichen Planus
Location: Fountain Valley CA, New Orleans LA, Birmingham AL,
Sponsor: Novartis Pharmaceuticals
Sex: All
Age: 18 - 70+
Code: NCT07775924
Phase2, Recruiting
Enhanced Recovery After Surgery (ERAS) for Complicated Appendicitis
for
Appendicitis Acute, Appendicitis Perforated,
Location: Los Angeles CA
Sponsor: Cedars-Sinai Medical Center
Sex: All
Age: 18+
Code: NCT06948071
Recruiting
WISPer: Evaluation of MTX-463 in Participants With Idiopathic Pulmonary Fibrosis (IPF)
for
Idiopathic Pulmonary Fibrosis
Location: Newport Beach CA, Los Angeles CA, Palm Springs CA,
Sponsor: Mediar Therapeutics
Sex: All
Age: 40+
Code: NCT06967805
Phase2, Recruiting
A Comparison of the dermaPACE® (Pulsed Acoustic Cellular Expression) Device in Conjunction With Standard of Care Versus Standard of Care Alone in the Treatment of Diabetic Foot Ulcers
for
Diabetic Foot Ulcers
Location: Long Beach CA, Los Angeles CA, San Bernardino CA,
Sponsor: SANUWAVE, Inc.
Sex: All
Age: 22+
Code: NCT01824407
Phase3, Recruiting
F18PET/CT Versus TC-MDP Scanning to Detect Bone Mets
for
Bone Metastases
Location: Los Angeles CA, Scottsdale AZ, Stanford CA,
Sponsor: American College of Radiology - Image Metrix
Sex: All
Age: 18+
Code: NCT00882609
Phase3, Recruiting
Identification of Pre-Malignant Lesions In Pediatric Patients With Neurofibromatosis Type 1 Using Novel Magnetic Resonance Imaging Techniques Paired With Artificial Intelligence
for
Neurofibromatosis Type 1
Location: Los Angeles CA
Sponsor: Nicole Baca
Sex: All
Age: 5 - 17
Code: NCT04763109
Recruiting
REVEAL: A Phase 3 Study of Obudanersen (ION582) in Angelman Syndrome
for
Angelman Syndrome
Location: Los Angeles CA, San Diego CA, Aurora CO, Vancouver,
Sponsor: Ionis Pharmaceuticals, Inc.
Sex: All
Age: 2 - 50
Code: NCT06914609
Phase3, Recruiting
An Eight-Week Study to Evaluate the Safety and Efficacy of VSJ-110 Compared to Placebo in the Treatment of Dry Eye
for
Dry Eye
Location: Newport Beach CA, Memphis TN
Sponsor: Vanda Pharmaceuticals
Sex: All
Age: 18+
Code: NCT07179055
Phase2, Recruiting
A Study Evaluating the Safety and Efficacy of PRV111, PRV211, and PRV131 in Subjects With Oral and Lung Cancers
for
Oral Squamous Cell Carcinoma
Location: Duarte CA, Chicago IL, Cleveland OH, Miami FL