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Paid Clinical Trials Irvine

Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM)

for
Glioblastoma (GBM)
Location: Newport Beach CA, Duarte CA, San Francisco CA,
Sponsor: Diakonos Oncology Corporation

Sex: All

Age: 18+

Code: NCT06805305

Phase2, Recruiting

Yttrium-90 (Y90) Radioembolization for the Treatment of Early Stage Renal Cell Carcinoma, The RENEGADE Trial

for
Stage I Renal Cell Cancer, Stage II Renal Cell Cancer
Location: Los Angeles CA, Aurora CO
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06432036

Phase1, Phase2, Recruiting

Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

for
Liver Neoplasms, Primary Liver Cancer, Secondary Liver Cancer,
Location: Newport Beach CA, Mission Viejo CA, Fullerton CA,
Sponsor: HistoSonics, Inc.

Sex: All

Age: 22+

Code: NCT06486454

Recruiting

Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

for
Psychosis Associated With Alzheimer's Disease
Location: Anaheim CA, Pasadena CA, Los Angeles CA,
Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All

Age: 55 - 70+

Code: NCT05980949

Phase3, Recruiting

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

for
Acute Myeloid Leukemia
Location: Los Angeles CA, Las Vegas NV, Fresno CA, Modesto CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06317649

Phase2, Recruiting

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Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes

for
Type 2 Diabetes Mellitus
Location: Newport Beach CA, Los Angeles CA, Santa Barbara CA,
Sponsor: Insulet Corporation

Sex: All

Age: 18 - 70+

Code: NCT07521475

Recruiting

Pancreatic Cancer Early Detection Consortium

for
Pancreas Cancer, Pancreas Cyst,
Location: Newport Beach CA, Orange CA, Duarte CA, Los Angeles CA,
Sponsor: Arbor Research Collaborative for Health

Sex: All

Age: 18 - 70+

Code: NCT04970056

Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of INV-9956 in Adult Patients With Advanced Metastatic Castration Resistant Prostate Cancer

for
Advanced Metastatic Castration Resistant Prostate Cancer
Location: Newport Beach CA, Orange CA, Scottsdale AZ, Spokane WA,
Sponsor: Shenzhen Ionova Life Sciences Co., Ltd.

Sex: Male

Age: 18+

Code: NCT06609005

Phase1, Phase2, Recruiting

Deep Brain Stimulation of the Amygdala for Combat Post-Traumatic Stress Disorder

for
Posttraumatic Stress Disorder
Location: Los Angeles CA
Sponsor: VA Greater Los Angeles Healthcare System

Sex: Male

Age: 25 - 70

Code: NCT02091843

Recruiting

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

for
Ulcerative Colitis, Ulcerative Colitis Chronic
Location: Orange CA, Garden Grove CA, Los Alamitos CA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 70+

Code: NCT06598943

Phase2, Recruiting

Impact of Ranolazine on Myocardial Ischemia Detected by High-Field 3T Cardiovascular Magnetic Resonance (CMR) Imaging and P-31 Spectroscopy

for
Angina, Heart Disease
Location: Beverly Hills CA
Sponsor: Westside Medical Associates of Los Angeles

Sex: All

Age: 18+

Code: NCT01804543

Recruiting

Clinical Study of the inQB8 TTVR System (The MonarQ Study)

for
Tricuspid Valve Regurgitation
Location: Los Angeles CA, Thousand Oaks CA, Plano TX, Atlanta GA,
Sponsor: inQB8 Medical Technologies, LLC

Sex: All

Age: 18+

Code: NCT06611579

Recruiting

Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation

for
Infusion Reactions
Location: Duarte CA, La Jolla CA, San Diego CA, Phoenix AZ,
Sponsor: New York Blood Center

Sex: All

Age: 0+

Code: NCT01656603

Phase2, Recruiting

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)

for
Breast Cancer
Location: Glendale CA, Sacramento CA, Albuquerque NM, El Paso TX,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06103864

Phase3, Recruiting

A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis

for
Myelofibrosis
Location: Newport Beach CA, Duarte CA, Los Angeles CA, Tucson AZ,
Sponsor: Sumitomo Pharma America, Inc.

Sex: All

Age: 18+

Code: NCT04176198

Phase1, Phase2, Recruiting

Pain and Major Depressive Disorder

for
Major Depressive Disorder, Chronic Pain
Location: Los Angeles CA
Sponsor: University of California, Los Angeles

Sex: All

Age: 18 - 70+

Code: NCT04556890

Recruiting

Open-Label Study of mRNA-3927 in Participants With Propionic Acidemia

for
Propionic Acidemia
Location: Los Angeles CA, Stanford CA, Houston TX, Edmonton,
Sponsor: ModernaTX, Inc.

Sex: All

Age: 0+

Code: NCT04159103

Phase1, Phase2, Recruiting

A Phase 1 Study of LNCB74 in Advanced Solid Tumors

for
Ovarian Cancer, Breast Cancer, Endometrial Cancer,
Location: Newport Beach CA, Salt Lake City UT, San Antonio TX,
Sponsor: NextCure, Inc.

Sex: All

Age: 18+

Code: NCT06774963

Phase1, Recruiting

Wound Irrigation With Saline Versus Hypodilute-chlorhexidine After Cesarean Section (WISHES Study)

for
Cesarean Section Complications, Cesarean Section; Infection
Location: Loma Linda CA
Sponsor: Loma Linda University

Sex: Female

Age: 18+

Code: NCT06339203

Recruiting

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

for
B-cell Acute Lymphoblastic Leukemia,
Location: Los Angeles CA, Salt Lake City UT, Aurora CO,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 0 - 25

Code: NCT06395103

Phase1, Phase2, Recruiting