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Paid Clinical Trials Irvine

Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

for
Breast Neoplasms, Triple Negative Breast Neoplasms,
Location: Newport Beach CA, Fullerton CA, Long Beach CA,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06966700

Phase3, Recruiting

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

for
Metastatic Colorectal Cancer
Location: Los Alamitos CA, Long Beach CA, Chandler AZ, Calgary,
Sponsor: Amgen

Sex: All

Age: 18+

Code: NCT06252649

Phase3, Recruiting

Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen

for
Carcinoid Syndrome, Carcinoid, Carcinoid Tumor,
Location: Newport Beach CA, Gilbert AZ, Salt Lake City UT,
Sponsor: Crinetics Pharmaceuticals Inc.

Sex: All

Age: 18+

Code: NCT07087054

Phase3, Recruiting

Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study

for
Moderate Aortic Valve Stenosis
Location: Newport Beach CA, Torrance CA, Pasadena CA,
Sponsor: Kardigan, Inc.

Sex: All

Age: 50+

Code: NCT07001800

Phase2, Phase3, Recruiting

Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors, Advanced Breast Cancer
Location: Newport Beach CA, San Francisco CA, Seattle WA,
Sponsor: Ensem Therapeutics

Sex: All

Age: 18+

Code: NCT06993844

Phase1, Phase2, Recruiting

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A Study to Evaluate the Efficacy and Safety of Rosnilimab (ANB030) in Treatment of Subjects With Moderate-to-Severe Alopecia Areata

for
Alopecia Areata
Location: Encinitas CA, Northridge CA, San Antonio TX, Tulsa OK,
Sponsor: AnaptysBio, Inc.

Sex: All

Age: 18 - 70+

Code: NCT05205070

Phase2, Recruiting

Anti-Inflammatory Dietary Intervention for Rheumatoid Arthritis

for
Rheumatoid Arthritis
Location: Beverly Hills CA
Sponsor: Attune Health Research, Inc.

Sex: All

Age: 18+

Code: NCT05291299

Recruiting

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

for
Mitral Valve Regurgitation
Location: Los Angeles CA, La Jolla CA, Thousand Oaks CA,
Sponsor: Medtronic Cardiovascular

Sex: All

Age: 18+

Code: NCT03242642

Recruiting

A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer

for
Gastroesophageal-junction Cancer, Monoclonal Antibody,
Location: Anaheim CA, Los Alamitos CA, Las Vegas NV, Greeley CO,
Sponsor: Shanghai Henlius Biotech

Sex: All

Age: 18+

Code: NCT06532006

Phase3, Recruiting

Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

for
Depressive Disorder, Major
Location: Anaheim CA, Colton CA, Glendale CA, Redlands CA,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18 - 70+

Code: NCT06559306

Phase3, Recruiting

BOOM-IBD2 Pivotal Clinical Trial

for
Ulcerative Colitis, Inflammatory Bowel Diseases
Location: Newport Beach CA, Los Angeles CA, Las Vegas NV,
Sponsor: Boomerang Medical

Sex: All

Age: 18 - 70+

Code: NCT06571669

Recruiting

A Study Evaluating the Safety and Efficacy of KITE-363 in Relapsed/Refractory Autoimmune Neurologic Diseases

for
Chronic Inflammatory Demyelinating Polyneuropathy,
Location: Newport Beach CA, Palo Alto CA, Salt Lake City UT,
Sponsor: Kite, A Gilead Company

Sex: All

Age: 18 - 70+

Code: NCT07304154

Phase1, Recruiting

Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease

for
Proteinuric Kidney Disease
Location: Los Angeles CA, Granada Hills CA, Las Vegas NV,
Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All

Age: 10 - 65

Code: NCT05312879

Phase2, Phase3, Recruiting

Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

for
Early Breast Cancer
Location: Orange CA, Fullerton CA, Cerritos CA, Duarte CA,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT05827081

Phase3, Recruiting

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

for
Advanced Solid Tumor, Advanced Malignant Neoplasm,
Location: Los Angeles CA, La Jolla CA, Denver CO, Portland OR,
Sponsor: PMV Pharmaceuticals, Inc

Sex: All

Age: 12+

Code: NCT04585750

Phase1, Phase2, Recruiting

Small Intestinal Bacterial Overgrowth (SIBO) in Pancreatic Adenocarcinoma (PDAC)

for
Pancreatic Adenocarcinoma, Weight Loss
Location: Los Angeles CA
Sponsor: Cedars-Sinai Medical Center

Sex: All

Age: 18+

Code: NCT06988150

Recruiting

A U.S. Pilot Human Investigation of RadiofrEquency Vapor Ablation System to Evaluate Safety, TOleRability, and Effectiveness for Proximal Intestinal Mucosal Ablation in Patients With Type 2 Diabetes Mellitus (RESTORE-1 Study)

for
Type-2 Diabetes Mellitus
Location: Newport Beach CA, Scottsdale AZ, Chapel Hill NC
Sponsor: Aqua Medical, Inc.

Sex: All

Age: 22 - 65

Code: NCT07355270

Recruiting

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

for
Intracranial Meningioma, Recurrent Meningioma,
Location: Torrance CA, Los Angeles CA, Burbank CA, La Jolla CA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT02523014

Phase2, Recruiting

Clinical Trial of N-803 Plus Tislelizumab or Prior Failed Immune Checkpoint Inhibitor and Docetaxel Versus Docetaxel Monotherapy in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Acquired Resistance to Immune Checkpoint In

for
NSCLC Stage IV
Location: Fountain Valley CA, El Segundo CA, Spokane WA,
Sponsor: ImmunityBio, Inc.

Sex: All

Age: 18 - 70+

Code: NCT06745908

Phase3, Recruiting

SLV-324 Treatment of Metastatic Solid Tumors

for
Metastatic Solid Tumors
Location: Newport Beach CA, Seattle WA, Houston TX, St Louis MO,
Sponsor: Solve Therapeutics

Sex: All

Age: 18+

Code: NCT07108114

Phase1, Recruiting