Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Clinical trials in Irvine address a diverse range of conditions, from mental health disorders and neurological diseases to skin conditions and cardiovascular issues. As one of California’s thriving research hubs, the city provides participants with a chance to explore cutting-edge therapies and receive specialized care, all while contributing to the advancement of medical science in their region.
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Results: 3,580
A US Non-interventional, Effectiveness and Safety Study of Patients Treated With SKYTROFA
for
Growth Hormone Deficiency
Location: Orange CA, Las Vegas NV, Phoenix AZ, San Francisco CA,
Suramin for the Treatment of Autism Trial: KZ101 in a Male Pediatric Population With Autism Spectrum Disorder (ASD)
for
Autism Spectrum Disorder (ASD)
Location: Orange CA, Baltimore MD
Sponsor: Children's Hospital of Orange County
Sex: Male
Age: 5 - 14
Code: NCT06866275
Phase2, Recruiting
A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Endometrial Cancer.
for
Endometrial Cancer
Location: Los Angeles CA, Phoenix AZ, Oklahoma City OK,
Sponsor: Iovance Biotherapeutics, Inc.
Sex: Female
Age: 18 - 70
Code: NCT06481592
Phase2, Recruiting
Featured
Evaluation of the Safety and Effectiveness of ARTIA Reconstructive Tissue Matrix Breast Reconstruction (ADORA) in Adult Participants
for
Breast Reconstruction
Location: Orange CA, Los Angeles CA, Palo Alto CA, Aurora CO,
Sponsor: AbbVie
Sex: Female
Age: 18+
Code: NCT06575192
Phase3, Recruiting
Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies
for
Advanced Solid Malignancies
Location: Los Angeles CA, San Francisco CA, San Antonio TX,
Sponsor: AstraZeneca
Sex: All
Age: 18 - 70+
Code: NCT05417594
Phase1, Phase2, Recruiting
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A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis
for
Uterine Fibroids, Endometriosis
Location: Long Beach CA, Lomita CA, Inglewood CA, Los Angeles CA,
Sponsor: Sumitomo Pharma Switzerland GmbH
Sex: Female
Age: 18 - 50
Code: NCT05862272
Phase3, Recruiting
Phase 1b/2a Randomized Double-blind Study to Investigate Safety Tolerability PK PD Preliminary Efficacy of Oral Administration of SNIPR001 in Patients With Hematologic Malignancy Scheduled for Allogeneic Hematopoietic Stem-Cell Transplant Receiving FQ Prophylaxis & Harboring FQR Ecoli Pre-Transplant
for
E Coli Infections, Allogenic Transplant Patients
Location: Duarte CA, San Francisco CA, Seattle WA, Houston TX,
Sponsor: SNIPR Biome Aps.
Sex: All
Age: 18+
Code: NCT06938867
Phase1, Phase2, Recruiting
A Study of Inlexisertib (DCC-3116) in Combination With Anticancer Therapies in Participants With Advanced Malignancies
for
GIST
Location: Los Angeles CA, Portland OR, St Louis MO,
Sponsor: Deciphera Pharmaceuticals, LLC
Sex: All
Age: 18+
Code: NCT05957367
Phase1, Phase2, Recruiting
Optimizing Reperfusion to Improve Outcomes and Neurologic Function
for
Acute Ischemic Stroke
Location: Long Beach CA, Los Angeles CA, Sacramento CA,
Sponsor: Corxel Pharmaceuticals
Sex: All
Age: 18 - 70+
Code: NCT06990867
Phase2, Phase3, Recruiting
Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer
for
Cervical Cancer
Location: Duarte CA, Las Vegas NV, Phoenix AZ, Scottsdale AZ,
Sponsor: Pfizer
Sex: Female
Age: 18+
Code: NCT06952660
Recruiting
Screening for AL Amyloidosis in Smoldering Multiple Myeloma
for
Smoldering Multiple Myeloma
Location: Los Angeles CA, San Francisco CA, Salt Lake City UT,
Sponsor: Tufts Medical Center
Sex: All
Age: 40+
Code: NCT06365060
Recruiting
Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)
for
Lung Non-Small Cell Carcinoma
Location: Loma Linda CA, La Jolla CA, Rancho Mirage CA,
Sponsor: SWOG Cancer Research Network
Sex: All
Age: 18+
Code: NCT06116682
Phase2, Recruiting
Clinical Trial to Compare the Efficacy of Celiprolol to Placebo in Patients With Vascular Ehlers-Danlos Syndrome
for
Vascular Ehlers-Danlos Syndrome
Location: Culver City CA
Sponsor: Acer Therapeutics Inc.
Sex: All
Age: 15 - 64
Code: NCT05432466
Phase3, Recruiting
Study of ITI-1284 as an Adjunctive Treatment in Patients With Generalized Anxiety Disorder
for
Generalized Anxiety Disorder
Location: Orange CA, Glendale CA, Redlands CA, Oceanside CA,
Sponsor: Intra-Cellular Therapies, Inc.
Sex: All
Age: 0+
Code: NCT06480383
Phase2, Recruiting
ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves
for
Aortic Valve Insufficiency, Aortic Valve Stenosis
Location: Newport Beach CA, Stanford CA, San Francisco CA,
Sponsor: Edwards Lifesciences
Sex: All
Age: 0+
Code: NCT05172973
Recruiting
Health Care Transition Readiness Short-Form Video Intervention
for
Health Care Transition Readiness, Health Literacy,
Location: Los Angeles CA
Sponsor: Children's Hospital Los Angeles
Sex: All
Age: 12 - 17
Code: NCT06842576
Recruiting
Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer
for
Non-small Cell Lung Cancer
Location: Orange CA, Los Alamitos CA, Los Angeles CA,
Sponsor: AstraZeneca
Sex: All
Age: 18+
Code: NCT06350097
Phase3, Recruiting
Study of the Theranostic Pair RYZ811 (Diagnostic) and RYZ801 (Therapeutic) to Identify and Treat Subjects With GPC3+ (Glypican-3) Unresectable HCC
for
Hepatocellular Carcinoma (HCC)
Location: Orange CA, Phoenix AZ, Tucson AZ, Seattle WA, Omaha NE,
Sponsor: RayzeBio, Inc.
Sex: All
Age: 18+
Code: NCT06726161
Phase1, Phase2, Recruiting
Phase Ib Study of the Safety of T-DXd and Immunotherapy Agents With and Without Chemotherapy in Advanced or Metastatic HER2+, Non-squamous NSCLC
for
Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Location: Orange CA, Houston TX, Fairfax VA, Baltimore MD,
Sponsor: AstraZeneca
Sex: All
Age: 18+
Code: NCT04686305
Phase1, Recruiting
A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis
for
Psychosis Associated With Alzheimer's Disease
Location: Orange CA, Anaheim CA, Long Beach CA, Murrieta CA,