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Paid Clinical Trials Irvine

Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma

for
Mantle Cell Lymphoma
Location: Beverly Hills CA, Los Angeles CA, Salt Lake City UT,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 60+

Code: NCT05976763

Phase3, Recruiting

Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

for
Neoplasms
Location: Duarte CA, Santa Monica CA, La Jolla CA, Phoenix AZ,
Sponsor: Celgene

Sex: All

Age: 0+

Code: NCT03435796

Phase2, Phase3, Recruiting

APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

for
Solid Tumors, Advanced Cancer, Renal Cancer, Gastric Cancer,
Location: Los Angeles CA, Edmonton, Winnipeg, Madison WI, Toronto,
Sponsor: Apollomics Inc.

Sex: All

Age: 18+

Code: NCT03175224

Phase2, Recruiting

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

for
Advanced Non-Small Cell Lung Cancer,
Location: Anaheim CA, Los Alamitos CA, Cerritos CA, Long Beach CA,
Sponsor: Mirati Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT04613596

Phase2, Phase3, Recruiting

A Dose Escalation Study of AV-380 in Cancer Patients With Cachexia

for
Cachexia
Location: Newport Beach CA, Lakewood CA, Beverly Hills CA,
Sponsor: AVEO Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT05865535

Phase1, Recruiting

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A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma

for
Endometrial Adenocarcinoma
Location: Newport Beach CA, Duarte CA, Los Angeles CA,
Sponsor: Acrivon Therapeutics

Sex: Female

Age: 18+

Code: NCT05548296

Phase2, Recruiting

Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)

for
Central Line Associated Blood Stream Infections (CLABSI)
Location: Los Angeles CA, Omaha NE, Sugarland TX, Rochester MN,
Sponsor: CorMedix Therapeutics

Sex: All

Age: 18+

Code: NCT06822426

Phase3, Recruiting

Evaluation of Cross-Linked Polyelectrolyte (CLP) With Placebo in Heart Failure Subjects

for
Heart Failure
Location: Tustin CA
Sponsor: Sorbent Therapeutics

Sex: All

Age: 21+

Code: NCT01736735

Phase2, Recruiting

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

for
Lymphoma, Non-Hodgkin, Multiple Myeloma, Advanced Solid Tumors
Location: Los Angeles CA, Santa Barbara CA, Phoenix AZ,
Sponsor: American Society of Clinical Oncology

Sex: All

Age: 12+

Code: NCT02693535

Phase2, Recruiting

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

for
Locally Advanced Lung Non-Small Cell Carcinoma,
Location: Los Angeles CA, Bakersfield CA, Kingman AZ, Modesto CA,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT05624996

Phase3, Recruiting

Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets

for
Brain Tumor, Non Small Cell Lung Cancer
Location: Newport Beach CA, Portland OR, Winston-Salem NC,
Sponsor: InSightec

Sex: All

Age: 18 - 70+

Code: NCT05317858

Phase3, Recruiting

Adapting Lifestyle Offloading for DFUs

for
Diabetic Foot Ulcer, Diabetic Foot
Location: Los Angeles CA
Sponsor: University of Southern California

Sex: All

Age: 21+

Code: NCT06278935

Recruiting

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

for
Ovarian Cancer, Pancreas Cancer, Urothelial Carcinoma,
Location: Newport CA, Los Angeles CA, San Antonio TX,
Sponsor: Nammi Therapeutics Inc

Sex: All

Age: 18+

Code: NCT06582017

Phase1, Recruiting

PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR

for
Aortic Stenosis, Calcific, Aortic Valve Stenosis
Location: Los Angeles CA, Rancho Mirage CA, Santa Barbara CA,
Sponsor: Edwards Lifesciences

Sex: All

Age: 65+

Code: NCT04889872

Recruiting

A Retrospective Trial to Evaluate the Micra Pacemaker

for
Pacemaker
Location: Newport Beach CA
Sponsor: Hoag Memorial Hospital Presbyterian

Sex: All

Age: 18+

Code: NCT04051814

Recruiting

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

for
Recurrent Lung Non-Small Cell Carcinoma,
Location: Torrance CA, Loma Linda CA, Beverly Hills CA,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT05642572

Phase2, Recruiting

mpMRI Compared to Diagnostic TURBT in Patients With Suspected Muscle-Invasive Bladder Cancer

for
Urothelial Bladder Cancer, Muscle-Invasive Bladder Cancer
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT06335667

Recruiting

Prospective Data Registry and Quality of Life Assessment of Patients Undergoing Radiotherapy With the RefleXion Medical Radiotherapy System

for
Cancer, Cancer Central Nervous System, Cancer Thoracic,
Location: Duarte CA, Palo Alto CA, Dallas TX, Pittsburgh PA,
Sponsor: RefleXion Medical

Sex: All

Age: 0+

Code: NCT05406167

Recruiting

Papaverine in Combination With Chemoradiation for the Treatment of Stage II-III Non-small Cell Lung Cancer

for
Locally Advanced Lung Non-Small Cell Carcinoma,
Location: Duarte CA, Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT05136846

Phase1, Recruiting

Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement

for
Aortic Stenosis, Coronary Artery Disease, Coronary Stenosis
Location: Torrance CA, Redlands CA, Santa Barbara CA, Phoenix AZ,
Sponsor: University of British Columbia

Sex: All

Age: 0+

Code: NCT04634240

Recruiting