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Paid Clinical Trials Irvine

Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)

for
Transthyretin-Mediated Amyloidosis, ATTR Amyloidosis
Location: Los Angeles CA, La Jolla CA, Austin TX, Houston TX,
Sponsor: Alnylam Pharmaceuticals

Sex: All

Age: 0+

Code: NCT04561518

Recruiting
New

Long-term Safety of Eplontersen Treated aTTR Patients and in Liver Transplant and Severely Hepatic Impaired Subpopulations

for
Transthyretin Amyloidosis,
Location: Los Angeles CA, Vancouver
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07654855

Recruiting

Analgesic Response to Opioid Analgesics in Buprenorphine-Maintained Individuals

for
Analgesic Response
Location: Los Angeles CA
Sponsor: University of California, Los Angeles

Sex: Male

Age: 20 - 50

Code: NCT02136784

Recruiting

Validation of Ejection Fraction and Cardiac Output Using Biostrap Wristband

for
Heart Failure
Location: Los Angeles CA
Sponsor: University of California, Los Angeles

Sex: All

Age: 18+

Code: NCT05279066

Recruiting

Study to Evaluate the Efficacy, Safety, and Tolerability of Efzofitimod in Patients With Systemic Sclerosis (SSc)-Related Interstitial Lung Disease (ILD) (SSc-ILD)

for
Interstitial Lung Disease
Location: Los Angeles CA, San Diego CA, Salt Lake City UT,
Sponsor: aTyr Pharma, Inc.

Sex: All

Age: 18+

Code: NCT05892614

Phase2, Recruiting

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A Study to Evaluate the Safety and Effectiveness of ALKS 2680 in Subjects With Idiopathic Hypersomnia

for
Idiopathic Hypersomnia
Location: Los Angeles CA, Phoenix AZ, Redwood City CA,
Sponsor: Alkermes, Inc.

Sex: All

Age: 18 - 70

Code: NCT06843590

Phase2, Recruiting

Standard Endoscopic Hemostasis Versus OVESCO Severe Non-variceal UGI Hemorrhage

for
Upper Gastrointestinal Hemorrhage
Location: Los Angeles CA
Sponsor: CURE Digestive Diseases Research Center

Sex: All

Age: 18 - 70+

Code: NCT03065465

Recruiting

An Open-label Dose Escalation/Expansion Trial to Evaluate the Safety and Anti-tumor Activity of TEV-56278 Alone or in Combination With Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

for
Advanced Solid Tumors
Location: Los Angeles CA, Milwaukee WI, Chicago IL, Nashville TN,
Sponsor: Teva Branded Pharmaceutical Products R&D LLC

Sex: All

Age: 18+

Code: NCT06480552

Phase1, Recruiting

The MIRROR Registry: Minimally Invasive IntRaceRebral HemORrhage Evacuation

for
Supratentorial Hemorrhage
Location: Burbank CA, Salt Lake City UT, Seattle WA,
Sponsor: Integra LifeSciences Corporation

Sex: All

Age: 18+

Code: NCT04494295

Recruiting

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

for
Breast Cancer, Solid Tumors, Adult
Location: Los Angeles CA, San Francisco CA, West Valley City UT,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT05768139

Phase1, Phase2, Recruiting

Efficacy of H7-Coil DTMS Compared to H1-Coil DTMS in Subjects With Major Depression Disorder (MDD)

for
Major Depressive Disorder (MDD)
Location: Los Angeles CA, La Jolla CA, Toronto, Charleston SC,
Sponsor: Brainsway

Sex: All

Age: 22 - 68

Code: NCT03012724

Recruiting

DETERMINE: Detemir vs NPH

for
Gestational Diabetes, Diabetes Mellitus, Type 2
Location: Los Angeles CA
Sponsor: University of California, Los Angeles

Sex: All

Age: 18+

Code: NCT05124457

Phase2, Recruiting
New

A Study to Asses Safety and Tolerability of ITI-1284 Given Alone or as an Additional Treatment in Participants With Generalized Anxiety Disorder (GAD)

for
Generalized Anxiety Disorder
Location: Los Angeles CA
Sponsor: Intra-Cellular Therapies, Inc.

Sex: All

Age: 18+

Code: NCT07807865

Phase3, Recruiting
New

Study of TUB-040 Given With Standard Ovarian Cancer Drugs in Patients With Fast-growing Ovarian Cancer

for
Ovarian Cancer
Location: Los Angeles CA, East Brunswick NJ, New York NY
Sponsor: Tubulis GmbH

Sex: Female

Age: 18+

Code: NCT07736937

Phase1, Phase2, Recruiting

The Happiest Baby, Inc. SNOO Postmarket Surveillance Study

for
Infant Death, Serious Injury
Location: Los Angeles CA
Sponsor: Happiest Baby, Inc.

Sex: All

Age: 18+

Code: NCT06361303

Recruiting

Thymus Regeneration, Immunorestoration, and Insulin Mitigation Extension Trial

for
Epigenetic Aging, Immunosenescence
Location: Torrance CA
Sponsor: Intervene Immune, Inc.

Sex: All

Age: 40 - 70+

Code: NCT04375657

Phase2, Recruiting

A Trial of Selinexor, Ruxolitinib and Methylprednisolone

for
Multiple Myeloma in Relapse, Multiple Myeloma, Refractory
Location: West Hollywood CA
Sponsor: Oncotherapeutics

Sex: All

Age: 0+

Code: NCT06225310

Phase1, Recruiting

Pilot Study Using Changes in Serum BCMA to Determine Disease Progression in Multiple Myeloma

for
Multiple Myeloma
Location: West Hollywood CA
Sponsor: Oncotherapeutics

Sex: All

Age: 18+

Code: NCT06209606

Early_phase1, Recruiting

Dextenza Within Upper Lid Canaliculus Compared With Lower Lid Canaliculus Following Bilateral Cataract Extraction Surgery With PCIOL.

for
Post-Surgical Ocular Pain, Post-Surgical Ocular Inflammation
Location: Beverly Hills CA
Sponsor: Kerry Assil, MD

Sex: All

Age: 18+

Code: NCT04592081

Recruiting

Safety and Effectiveness of the CustomFlex Artificial Iris Prosthesis for the Treatment of Iris Defects

for
Full Aniridia, Partial Aniridia
Location: Los Angeles CA, Cincinnati OH, Philadelphia PA
Sponsor: Clinical Research Consultants, Inc.

Sex: All

Age: 3+

Code: NCT01860612

Recruiting