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Paid Clinical Trials Orange County

Discover 3,560 paid clinical trials in Orange County, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

for
Glioma, Astrocytoma, Grade IV, IDH1-mutant Glioma,
Location: Newport Beach CA, Los Angeles CA, La Jolla CA,
Sponsor: Nuvation Bio Inc.

Sex: All

Age: 18+

Code: NCT05303519

Phase3, Recruiting
Active & Responsive

A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

for
Ulcerative Colitis
Location: Newport Beach CA, Los Angeles CA, Sun City AZ,
Sponsor: Takeda

Sex: All

Age: 18 - 65

Code: NCT06095128

Recruiting
Active & Responsive

A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03)

for
Extensive Stage-small Cell Lung Cancer
Location: Newport Beach CA, Phoenix AZ, Vancouver WA,
Sponsor: Daiichi Sankyo

Sex: All

Age: 18+

Code: NCT06362252

Phase1, Phase2, Recruiting
Active & ResponsiveNew

Blood and Cystic Fluid From Patients Undergoing Surgery for Worrisome Pancreatic Cysts

for
Pancreatic Cyst
Location: Newport Beach CA, Atlanta GA
Sponsor: Translational Genomics Research Institute

Sex: All

Age: 18+

Code: NCT07767227

Recruiting
Active & Responsive

LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC

for
Metastatic Non-small Cell Lung Cancer
Location: Newport Beach CA, Fullerton CA, Goodyear AZ,
Sponsor: NovoCure GmbH

Sex: All

Age: 18+

Code: NCT06216301

Phase3, Recruiting

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Active & Responsive

Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial

for
Myopia
Location: Fullerton CA, Berkeley CA, Houston TX, Memphis TN,
Sponsor: Ohio State University

Sex: All

Age: 6 - 11

Code: NCT07567040

Phase3, Recruiting
Active & Responsive

Study of EVO756 in Adults With Migraine

for
Migraine
Location: Buena Park CA, Los Angeles CA, Fresno CA, Chandler AZ,
Sponsor: Evommune, Inc.

Sex: All

Age: 18 - 64

Code: NCT07616128

Phase2, Recruiting
Active & Responsive

A Research Study on How Well Different Doses of the Medicine UBT251 Help People Living With Overweight or Obesity

for
Overweight, Obesity
Location: Cypress CA, Overland Park KS, Montreal
Sponsor: Novo Nordisk A/S

Sex: All

Age: 18 - 65

Code: NCT07395687

Phase2, Recruiting
Active & ResponsiveNew

A Phase 2, Open-Label, Single-Arm Trial of FT819 in Participants With Lupus Nephritis

for
Lupus Nephritis, Systemic Lupus Erythematosus,
Location: Fullerton CA, Fontana CA, Beverly Hills CA,
Sponsor: Fate Therapeutics

Sex: All

Age: 12 - 70

Code: NCT07570862

Phase2, Recruiting
Active & Responsive

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

for
Breast Neoplasms, Brain Neoplasms, Neoplasms by Site, Neoplasms,
Location: Fullerton CA, Los Angeles CA, Houston TX, Urbana IL,
Sponsor: Stemline Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05386108

Phase1, Phase2, Recruiting
Active & Responsive

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

for
Carcinoma, Non-Small-Cell Lung
Location: Fullerton CA, Long Beach CA, Los Angeles CA, Gilbert AZ,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06623422

Phase3, Recruiting
Active & Responsive

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

for
Breast Neoplasms
Location: Fullerton CA, Los Alamitos CA, Chandler AZ, Gilbert AZ,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06312176

Phase3, Recruiting
Active & Responsive

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

for
Breast Cancer, Endometrial Cancer, Ovarian Cancer,
Location: Irvine CA, Duarte CA, West Valley City UT,
Sponsor: Terremoto Biosciences Inc.

Sex: All

Age: 18+

Code: NCT07109726

Phase1, Phase2, Recruiting
Active & Responsive

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

for
Triple Negative Breast Neoplasms
Location: Irvine CA, Duarte CA, Los Angeles CA, Las Vegas NV,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06841354

Phase3, Recruiting
Active & Responsive

DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

for
Ductal Carcinoma in Situ
Location: Irvine CA, Duarte CA, South Pasadena CA, Los Angeles CA,
Sponsor: QuantumLeap Healthcare Collaborative

Sex: Female

Age: 18+

Code: NCT06075953

Phase2, Recruiting
Active & Responsive

Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

for
Myelofibrosis; Anemia, Anemia, Myelofibrosis,
Location: Irvine CA, Duarte CA, Los Angeles CA, Gilbert AZ,
Sponsor: Disc Medicine, Inc

Sex: All

Age: 18+

Code: NCT05320198

Phase1, Phase2, Recruiting
Active & Responsive

Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

for
Extensive Stage Lung Small Cell Carcinoma,
Location: Irvine CA, Duarte CA, La Jolla CA, Sacramento CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06287775

Phase1, Phase2, Recruiting
Active & Responsive

A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)

for
Coronavirus Disease (COVID-19)
Location: Los Alamitos CA, Northridge CA, Westlake Village CA,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06667700

Phase3, Recruiting
Active & Responsive

A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults

for
Psoriatic Arthritis, Axial Spondyloarthritis
Location: Fullerton CA, Whittier CA, Covina CA, Upland CA,
Sponsor: UCB Biopharma SRL

Sex: All

Age: 18+

Code: NCT07290036

Phase1, Recruiting
Active & Responsive

A Study of LY4088044 in Healthy Participants

for
Healthy
Location: Los Alamitos CA, Salt Lake City UT, San Antonio TX
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 65

Code: NCT07090785

Phase1, Recruiting