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Paid Clinical Trials Orange County

Discover 3,614 paid clinical trials in Orange County, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03)

for
Extensive Stage-small Cell Lung Cancer
Location: Newport Beach CA, Phoenix AZ, Vancouver WA,
Sponsor: Daiichi Sankyo

Sex: All

Age: 18+

Code: NCT06362252

Phase 1, Phase 2, Recruiting
Active & Responsive

LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC

for
Metastatic Non-small Cell Lung Cancer
Location: Newport Beach CA, Fullerton CA, Goodyear AZ,
Sponsor: NovoCure GmbH

Sex: All

Age: 18+

Code: NCT06216301

Phase 3, Recruiting
Active & Responsive

Blood and Cystic Fluid From Patients Undergoing Surgery for Worrisome Pancreatic Cysts

for
Pancreatic Cyst
Location: Newport Beach CA, Atlanta GA
Sponsor: Translational Genomics Research Institute

Sex: All

Age: 18+

Code: NCT07767227

Recruiting
Active & Responsive

Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial

for
Myopia
Location: Fullerton CA, Palo Alto CA, Berkeley CA, Houston TX,
Sponsor: Ohio State University

Sex: All

Age: 6 - 11

Code: NCT07567040

Phase 3, Recruiting
Active & Responsive

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

for
Breast Neoplasms, Brain Neoplasms, Neoplasms by Site, Neoplasms,
Location: Fullerton CA, Los Angeles CA, Houston TX, Urbana IL,
Sponsor: Stemline Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05386108

Phase 1, Phase 2, Recruiting

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Active & Responsive

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

for
Carcinoma, Non-Small-Cell Lung
Location: Fullerton CA, Long Beach CA, Los Angeles CA, Gilbert AZ,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06623422

Phase 3, Recruiting
Active & Responsive

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

for
Breast Neoplasms
Location: Fullerton CA, Chandler AZ, Gilbert AZ, Denver CO,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06312176

Phase 3, Recruiting
Active & Responsive

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

for
Breast Cancer, Endometrial Cancer, Ovarian Cancer,
Location: Irvine CA, Duarte CA, West Valley City UT,
Sponsor: Terremoto Biosciences Inc.

Sex: All

Age: 18+

Code: NCT07109726

Phase 1, Phase 2, Recruiting
Active & Responsive

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

for
Triple Negative Breast Neoplasms
Location: Irvine CA, Duarte CA, Los Angeles CA, Las Vegas NV,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06841354

Phase 3, Recruiting
Active & Responsive

DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

for
Ductal Carcinoma in Situ
Location: Irvine CA, Duarte CA, South Pasadena CA, Los Angeles CA,
Sponsor: QuantumLeap Healthcare Collaborative

Sex: Female

Age: 18+

Code: NCT06075953

Phase 2, Recruiting
Active & Responsive

Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

for
Myelofibrosis; Anemia, Anemia, Myelofibrosis,
Location: Irvine CA, Duarte CA, Los Angeles CA, Gilbert AZ,
Sponsor: Disc Medicine, Inc

Sex: All

Age: 18+

Code: NCT05320198

Phase 1, Phase 2, Recruiting
Active & Responsive

Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

for
Extensive Stage Lung Small Cell Carcinoma,
Location: Irvine CA, Duarte CA, La Jolla CA, Sacramento CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06287775

Phase 1, Phase 2, Recruiting
Active & Responsive

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer

for
Metastatic Breast Cancer
Location: Irvine CA, Duarte CA, Los Angeles CA, La Jolla CA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT03424005

Phase 1, Phase 2, Recruiting
Active & Responsive

Study of Safety and PK of AZD0543 in Healthy Adults

for
Human Metapneumovirus Infection
Location: Los Alamitos CA, South Miami FL
Sponsor: AstraZeneca

Sex: All

Age: 18 - 55

Code: NCT07824622

Phase 1, Recruiting
Active & Responsive

A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)

for
Coronavirus Disease (COVID-19)
Location: Los Alamitos CA, Northridge CA, Westlake Village CA,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06667700

Phase 3, Recruiting
Active & Responsive

A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults

for
Psoriatic Arthritis, Axial Spondyloarthritis
Location: Fullerton CA, Whittier CA, Covina CA, Upland CA,
Sponsor: UCB Biopharma SRL

Sex: All

Age: 18+

Code: NCT07290036

Phase 1, Recruiting
Active & Responsive

A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations

for
Parkinson Disease
Location: Los Alamitos CA, Los Angeles CA, Carlsbad CA,
Sponsor: Appello Pharmaceuticals, Inc.

Sex: All

Age: 30 - 70+

Code: NCT07432958

Phase 2, Recruiting
Active & Responsive

A Study to Assess the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine

for
Migraine
Location: Fullerton CA, Long Beach CA, Canoga Park CA,
Sponsor: TriGemX Bio, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07816367

Phase 3, Recruiting
Active & Responsive

A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

for
NASH With Fibrosis, MASH With Fibrosis
Location: Orange CA, Long Beach CA, Los Angeles CA, Pasadena CA,
Sponsor: Akero Therapeutics, Inc

Sex: All

Age: 18 - 70+

Code: NCT06215716

Phase 3, Recruiting
Active & Responsive

A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)

for
Major Depressive Disorder
Location: Orange CA, Santa Monica CA, San Diego CA, Las Vegas NV,
Sponsor: Definium Therapeutics US, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07592689

Phase 3, Recruiting