Discover 3,614 paid clinical trials in Orange County, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Orange County offers clinical trials for a variety of conditions, including high blood pressure, heart disease, and skin disorders such as eczema, alopecia, and psoriasis. The city’s medical institutions are actively recruiting both healthy volunteers, as well as those with specific health needs to participate in studies that could improve treatments and outcomes for these, and many other widespread health issues.
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Results: 3,614
Active & Responsive
Diagnostic Performance Study of the EMVision Emu™ Brain Scanner in the Detection of Intracranial Hemorrhage in Suspected Stroke Patients
for
Stroke, Hemorrhagic Stroke
Location: Los Angeles CA, Houston TX, Jacksonville FL,
Sponsor: EMVision Medical Devices Ltd
Sex: All
Age: 22+
Code: NCT06999122
Recruiting
Active & Responsive
PiMZ Longitudinal Cohort (PiMZ Logic)
for
Alpha 1-Antitrypsin Deficiency, Emphysema or COPD
Location: Los Angeles CA
Sponsor: Columbia University
Sex: All
Age: 18+
Code: NCT06505603
Recruiting
Active & Responsive
Vorasidenib Study in Pediatric Participants With Grade 2 Astrocytoma or Oligodendroglioma With an IDH1 or IDH2 Mutation
for
Grade 2 Astrocytoma or Oligodendroglioma With an IDH1 or IDH2 Mutation,
Location: Los Angeles CA, Minneapolis MN, Chicago IL, Boston MA
Sponsor: Institut de Recherches Internationales Servier (I.R.I.S.)
Sex: All
Age: 12 - 17
Code: NCT07286292
Phase 2, Recruiting
Active & Responsive
Myeloablative Conditioning, Prophylactic Defibrotide and Haplo AlloSCT for Patients With Sickle Cell Disease
for
Sickle Cell Disease
Location: Los Angeles CA, Milwaukee WI, Gainesville FL,
Sponsor: New York Medical College
Sex: All
Age: 0 - 21
Code: NCT02675959
Phase 2, Recruiting
Active & Responsive
A Study to Learn About the Study Medicine Called Rimegepant in Adults When Used for the Prevention of Chronic Migraine
for
Preventive Treatment of Migraine
Location: Los Angeles CA, Canoga Park CA, Fresno CA,
Sponsor: Pfizer
Sex: All
Age: 18+
Code: NCT07729462
Phase 3, Recruiting
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Active & Responsive
Phase 1 Study of a Self-amplifying RNA Vaccine (ITI-5000) in Stage 2-3 Triple Negative Breast Cancer
for
Triple Negative Breast Cancer (TNBC)
Location: Los Angeles CA, San Antonio TX, Nashville TN,
Sponsor: Immunomic Therapeutics, Inc.
Sex: Female
Age: 18+
Code: NCT07652242
Phase 1, Recruiting
Active & Responsive
A Phase 1 and 2 Study of VMD-102 in Hepatocellular Carcinoma and Other Solid Tumors
Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors
for
Advanced Solid Tumors
Location: Los Angeles CA, San Francisco CA, Aurora CO,
Sponsor: ModernaTX, Inc.
Sex: All
Age: 12+
Code: NCT05533697
Phase 1, Phase 2, Recruiting
Active & Responsive
Interleukin-6 Receptor Inhibitor Sarilumab in Combination With Ipilimumab, Nivolumab and Relatlimab in Patients With Unresectable Stage III or Stage IV Melanoma
for
Melanoma, Unresectable Melanoma
Location: Los Angeles CA, New York NY, Boston MA
Sponsor: NYU Langone Health
Sex: All
Age: 18 - 70+
Code: NCT05428007
Phase 2, Recruiting
Active & Responsive
Study of Patritumab Deruxtecan Plus Pembrolizumab With Other Anticancer Agents in Participants With High-Risk Early-Stage Triple-Negative or Hormone Receptor-Low Positive/HER-2 Negative Breast Cancer (MK-1022-010, HERTHENA-Breast-03)
for
Breast Neoplasms, Breast Cancer
Location: Santa Monica CA, Tigard OR, Billings MT, Dallas TX,
Sponsor: Merck Sharp & Dohme LLC
Sex: All
Age: 18+
Code: NCT06797635
Phase 2, Recruiting
Active & Responsive
A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Narcolepsy
for
EDS, Cataplexy, Fatigue, Narcolepsy
Location: Los Angeles CA, Peoria AZ, Redwood City CA,
Sponsor: Harmony Biosciences Management, Inc.
Sex: All
Age: 18+
Code: NCT07675135
Phase 3, Recruiting
Active & Responsive
A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B)
for
Esophageal Squamous Cell Carcinoma
Location: Los Angeles CA, Tucson AZ, Pittsburgh PA,
Sponsor: Merck Sharp & Dohme LLC
Sex: All
Age: 18+
Code: NCT05319730
Phase 1, Phase 2, Recruiting
Active & Responsive
A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors
for
Solid Tumor, Non-Small-Cell Lung Cancer,
Location: Santa Monica CA, Irving TX, St Louis MO, Jefferson LA,
Sponsor: Astellas Pharma Inc
Sex: All
Age: 18+
Code: NCT07094204
Phase 1, Recruiting
Active & Responsive
Pembrolizumab and Pemetrexed for Progressive Chordoma
for
Chordomas, Chordoma
Location: Santa Monica CA
Sponsor: Saint John's Cancer Institute
Sex: All
Age: 18+
Code: NCT06794645
Phase 2, Recruiting
Active & Responsive
Clinical Trial Exploring the Outpatient Treatment of Phantom Limb Pain With Ketamine Administration in a Six Month Study With a Minimum Remission Period of 7 Days Between Treatment Session. 25-30 Subjects With an Ongoing History of Significant PLP.--FDA and IRB Approved.
for
Phantom Limb Syndrome With Pain
Location: Santa Monica CA, Sacramento CA, San Anselmo CA,
Sponsor: The Ketamine Research Foundation
Sex: All
Age: 18 - 65
Code: NCT07276542
Phase 2, Phase 3, Recruiting
Active & Responsive
A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc Disease
for
Degenerative Disc Disease
Location: Santa Monica CA, Thousand Oaks CA, Phoenix AZ,
Sponsor: DiscGenics, Inc.
Sex: All
Age: 18 - 70+
Code: NCT07254806
Phase 3, Recruiting
Active & Responsive
Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis
for
Knee Cartilage Defects
Location: Santa Monica CA, Encinitas CA, La Jolla CA, La Mesa CA,
Sponsor: Medipost, Inc.
Sex: All
Age: 18 - 70+
Code: NCT07339111
Phase 3, Recruiting
Active & Responsive
A Single Dose of BRTX 100 for Patients With Chronic Lumbar Disc Disease (cLDD)
for
Lumbar Disc Disease
Location: Santa Monica CA, Walnut Creek CA, Greenwood Village CO,
Sponsor: BioRestorative Therapies
Sex: All
Age: 18+
Code: NCT04042844
Phase 2, Recruiting
Active & Responsive
Metronomic Gemcitabine, Mitomycin C, and Thalidomide for Advanced Solid Tumors
for
Solid Tumor Cancer
Location: Santa Monica CA
Sponsor: Sarcoma Oncology Research Center, LLC
Sex: All
Age: 18+
Code: NCT07671534
Phase 2, Recruiting
Active & Responsive
A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression