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Paid Clinical Trials Orange County

Discover 3,560 paid clinical trials in Orange County, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

Study of Patritumab Deruxtecan Plus Pembrolizumab With Other Anticancer Agents in Participants With High-Risk Early-Stage Triple-Negative or Hormone Receptor-Low Positive/HER-2 Negative Breast Cancer (MK-1022-010, HERTHENA-Breast-03)

for
Breast Neoplasms, Breast Cancer
Location: Santa Monica CA, Tigard OR, Billings MT, Dallas TX,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06797635

Phase2, Recruiting
Active & Responsive

A Trial to Evaluate Efficacy and Safety of Maridebart Cafraglutide in Adults Living With Elevated Liver Fat and Obesity or Overweight

for
Overweight or Obesity and Elevated Liver Fat
Location: Rialto CA, Canoga Park CA, Escondido CA, San Diego CA,
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT07441252

Phase2, Recruiting
Active & Responsive

A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Narcolepsy

for
EDS, Cataplexy, Fatigue, Narcolepsy
Location: Los Angeles CA, Peoria AZ, Redwood City CA,
Sponsor: Harmony Biosciences Management, Inc.

Sex: All

Age: 18+

Code: NCT07675135

Phase3, Recruiting
Active & Responsive

A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B)

for
Esophageal Squamous Cell Carcinoma
Location: Los Angeles CA, Tucson AZ, Pittsburgh PA,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT05319730

Phase1, Phase2, Recruiting
Active & Responsive

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

for
Solid Tumor, Non-Small-Cell Lung Cancer,
Location: Santa Monica CA, Irving TX, St Louis MO, Jefferson LA,
Sponsor: Astellas Pharma Inc

Sex: All

Age: 18+

Code: NCT07094204

Phase1, Recruiting

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Active & Responsive

Pembrolizumab and Pemetrexed for Progressive Chordoma

for
Chordomas, Chordoma
Location: Santa Monica CA
Sponsor: Saint John's Cancer Institute

Sex: All

Age: 18+

Code: NCT06794645

Phase2, Recruiting
Active & Responsive

Clinical Trial Exploring the Outpatient Treatment of Phantom Limb Pain With Ketamine Administration in a Six Month Study With a Minimum Remission Period of 7 Days Between Treatment Session. 25-30 Subjects With an Ongoing History of Significant PLP.--FDA and IRB Approved.

for
Phantom Limb Syndrome With Pain
Location: Santa Monica CA, Sacramento CA, San Anselmo CA,
Sponsor: The Ketamine Research Foundation

Sex: All

Age: 18 - 65

Code: NCT07276542

Phase2, Phase3, Recruiting
Active & Responsive

A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc Disease

for
Degenerative Disc Disease
Location: Santa Monica CA, Thousand Oaks CA, Phoenix AZ,
Sponsor: DiscGenics, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07254806

Phase3, Recruiting
Active & Responsive

Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis

for
Knee Cartilage Defects
Location: Santa Monica CA, Encinitas CA, La Jolla CA, La Mesa CA,
Sponsor: Medipost, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07339111

Phase3, Recruiting
Active & Responsive

A Single Dose of BRTX 100 for Patients With Chronic Lumbar Disc Disease (cLDD)

for
Lumbar Disc Disease
Location: Santa Monica CA, Walnut Creek CA, Greenwood Village CO,
Sponsor: BioRestorative Therapies

Sex: All

Age: 18+

Code: NCT04042844

Phase2, Recruiting
Active & Responsive

Metronomic Gemcitabine, Mitomycin C, and Thalidomide for Advanced Solid Tumors

for
Solid Tumor Cancer
Location: Santa Monica CA
Sponsor: Sarcoma Oncology Research Center, LLC

Sex: All

Age: 18+

Code: NCT07671534

Phase2, Recruiting
Active & Responsive

A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

for
Solid Tumor, Adult, Colorectal Cancer, Non-Small Cell Lung,
Location: Los Angeles CA, La Jolla CA, Gilbert AZ, Seattle WA,
Sponsor: A2 Biotherapeutics Inc.

Sex: All

Age: 18+

Code: NCT06682793

Phase1, Phase2, Recruiting
Active & Responsive

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

for
Solid Tumor, Adult, Colorectal Cancer,
Location: Santa Monica CA, La Jolla CA, Phoenix AZ, Palo Alto CA,
Sponsor: A2 Biotherapeutics Inc.

Sex: All

Age: 18+

Code: NCT04981119

Recruiting
Active & Responsive

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

for
Solid Tumor, Adult, Colorectal Cancer, NSCLC,
Location: Los Angeles CA, La Jolla CA, Stanford CA, Gilbert AZ,
Sponsor: A2 Biotherapeutics Inc.

Sex: All

Age: 18+

Code: NCT06051695

Phase1, Phase2, Recruiting
Active & Responsive

Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

for
Lactating Women on Select DOI,
Location: Loma Linda CA, La Jolla CA, Salt Lake City UT,
Sponsor: Duke University

Sex: All

Age: 0+

Code: NCT03511118

Recruiting
Active & Responsive

BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies

for
Healthy
Location: Loma Linda CA, Lancaster CA, Phoenix AZ, Palo Alto CA,
Sponsor: Pfizer

Sex: All

Age: 0 - 49

Code: NCT07160244

Phase3, Recruiting
Active & Responsive

Hemoglobin Maintenance in Pediatric ESRD (End-stage Renal Disease) Patients by Ferric Pyrophosphate Citrate (FPC)

for
End Stage Renal Disease
Location: Loma Linda CA, Seattle WA, San Antonio TX,
Sponsor: Rockwell Medical Technologies, Inc.

Sex: All

Age: 0 - 17

Code: NCT04239391

Phase3, Recruiting
Active & Responsive

Gastroschisis Outcomes of Delivery (GOOD) Study

for
Gastroschisis
Location: Loma Linda CA, Stanford CA, Salt Lake City UT,
Sponsor: Medical College of Wisconsin

Sex: Female

Age: 18+

Code: NCT02774746

Recruiting
Active & Responsive

A Pivotal Study to Evaluate the Effectiveness of Isometric Handgrip Therapy in Elevated Blood Pressure and Hypertensive Subjects

for
Elevated Blood Pressure, Hypertension
Location: Valley Village CA, West Hills CA, Dallas TX, Houston TX,
Sponsor: Zona Health, Inc

Sex: All

Age: 22+

Code: NCT06843577

Recruiting
Active & Responsive

Detection and Risk Stratification in Veterans Presenting With Microscopic Hematuria

for
Urothelial Carcinoma
Location: Murrieta CA, San Antonio TX, Durham NC, Garden City NY
Sponsor: Pacific Edge Limited

Sex: All

Age: 18 - 70+

Code: NCT05889195

Recruiting