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Paid Clinical Trials Orange County

Discover 3,617 paid clinical trials in Orange County, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Metronomic Cyclophosphamide With Pembrolizumab in Checkpoint Inhibitor Refractory Melanoma

for
Melanoma, Melanoma Stage III, Melanoma (Skin),
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT06771544

Phase 2, Recruiting

Genetic Testing to Select Therapy for the Treatment of Advanced or Metastatic Kidney Cancer, OPTIC RCC Study

for
Advanced Clear Cell Renal Cell Carcinoma,
Location: Orange CA, Duarte CA, Dallas TX, Nashville TN,
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All

Age: 18+

Code: NCT05361720

Phase 2, Recruiting

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

for
Non-Muscle Invasive Bladder Urothelial Carcinoma,
Location: Orange CA, Irvine CA, Los Angeles CA, Bakersfield CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06770582

Phase 2, Recruiting

Impact of Personality on Adherence to Tyrosine Kinase Inhibitor Therapy in Pts w/Chronic Myeloid Leukemia

for
Chronic Myeloid Leukemia,
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT06229860

Recruiting

CMV-TCIP Directed Letermovir Prophylaxis After Allo-SCT

for
CMV, Allogeneic Stem Cell Transplantation
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT06453460

Phase 2, Recruiting

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Pilot Comparing ctDNA IDV vs. SPV Sample in Pts Undergoing Biopsies for Hepatobiliary and Pancreatic Cancers

for
Hepatobiliary Cancer, Pancreatic Cancer,
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT05497531

Recruiting

VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

for
Advanced Melanoma
Location: Orange CA, Los Angeles CA, La Jolla CA, Palo Alto CA,
Sponsor: Replimune, Inc.

Sex: All

Age: 12+

Code: NCT06264180

Phase 3, Recruiting

PilotStudyAssessSafeActiveSurveillancApproachLocalThe Pa w/BrainMetsUndergoinCNSPenetratSystemicThe

for
Brain Cancer, Brain Cancer Metastatic, Nervous System Cancer,
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT07827001

Recruiting

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma

for
Glioblastoma, IDH-Wildtype, MGMT-Unmethylated Glioblastoma
Location: Orange CA, Irvine CA, Los Angeles CA, Sacramento CA,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT07452458

Phase 3, Recruiting

Treating Anemia in Myelofibrosis With Repurposed Drugs (Nelfinavir) That Restore Iron Delivery to the Bone Marrow

for
Myelofibrosis, Myelofibrosis; Anemia
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT07281781

Phase 1, Phase 2, Recruiting

A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)

for
Accelerated Phase Myeloproliferative Neoplasm,
Location: Orange CA, Irvine CA, Palo Alto CA, Sacramento CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06661915

Phase 2, Recruiting

L19IL2/L19TNF in Patients With Cutaneous Squamous Cell Carcinoma

for
Locally Advanced Cutaneous Squamous Cell Carcinoma
Location: Orange CA, Houston TX, Atlanta GA, Durham NC, Boston MA
Sponsor: Philogen S.p.A.

Sex: All

Age: 18+

Code: NCT07228442

Phase 2, Recruiting

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

for
Metastatic Malignant Solid Neoplasm,
Location: Orange CA, Irvine CA, Duarte CA, Sacramento CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05372614

Phase 1, Recruiting

Testing the Effect of Teclistamab on Recurrent Plasmablastic Lymphoma

for
Recurrent Plasmablastic Lymphoma,
Location: Orange CA, Irvine CA, Duarte CA, Los Angeles CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07332507

Phase 1, Recruiting

Metformin in Pseudomyxoma Peritonei Secondary to Appendiceal Mucinous Neoplasms

for
Appendiceal Mucinous Neoplasm, Pseudomyxoma Peritonei
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT07693452

Phase 2, Recruiting

Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

for
Astrocytoma, IDH-Mutant, Grade 2,
Location: Orange CA, Irvine CA, Duarte CA, La Jolla CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06860594

Phase 1, Recruiting

Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer

for
Astrocytoma, IDH-Mutant, Grade 3
Location: Orange CA, Irvine CA, Anaheim CA, Bellflower CA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 12+

Code: NCT07215910

Phase 3, Recruiting

Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

for
Metastatic Castration-Resistant Prostate Carcinoma,
Location: Orange CA, Irvine CA, Los Angeles CA, La Jolla CA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: Male

Age: 18+

Code: NCT07200830

Phase 3, Recruiting

Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial

for
Anatomic Stage II Breast Cancer AJCC v8,
Location: Orange CA, Irvine CA, Yorba Linda CA, Pasadena CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07391774

Phase 3, Recruiting

Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors

for
Adenocarcinoma, Basal Cell Carcinoma, Squamous Cell Carcinoma,
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT07628634

Early Phase 1, Recruiting