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Paid Clinical Trials Orange County

Discover 3,617 paid clinical trials in Orange County, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal Cancer

for
Metastatic Colorectal Adenocarcinoma,
Location: Orange CA, Irvine CA, Costa Mesa CA, Los Angeles CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06102902

Phase 1, Recruiting

Testing the Safety and Feasibility of Immunotherapy Drugs, Botensilimab and Balstilimab, Before Surgery for Clear Cell Renal Cell Carcinoma, NEO RoBOT Trial

for
Clear Cell Renal Cell Carcinoma,
Location: Orange CA, Irvine CA, Oklahoma City OK, Gainesville FL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07516366

Phase 2, Recruiting

ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Orange CA, Irvine CA, Yorba Linda CA, La Jolla CA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT06876714

Phase 3, Recruiting

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

for
Locally Advanced Cervical Adenocarcinoma,
Location: Orange CA, Irvine CA, Bellflower CA, Corona CA,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT07061977

Phase 3, Recruiting

ProofPrincip IntraTu TCells SinglDoseImmunCheckpoinInhib Gastro-Esophage Adenocarcinoma w/ARID1a Mu

for
Solid Tumor, Adult, Malignant Solid Tumor,
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT06824363

Early Phase 1, Recruiting

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Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

for
Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma,
Location: Orange CA, Irvine CA, La Jolla CA, Santa Barbara CA,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT06958328

Phase 3, Recruiting

A Study to Find Out if Enfortumab Vedotin Given With Pembrolizumab Helps People With Muscle-invasive Bladder Cancer Keep Their Bladder

for
Muscle-invasive Bladder Cancer
Location: Orange CA, Stanford CA, San Antonio TX, Round Rock TX,
Sponsor: Astellas Pharma Global Development, Inc.

Sex: All

Age: 18+

Code: NCT07475806

Phase 2, Recruiting

Phase 3 Study of Taletrectinib vs Placebo as an Adjuvant Therapy in ROS1 Positive NSCLC (TRUST-IV)

for
Non-small Cell Lung Cancer (NSCLC)
Location: Orange CA, Los Angeles CA, Boise ID, Austin TX,
Sponsor: Nuvation Bio Inc.

Sex: All

Age: 18+

Code: NCT07154706

Phase 3, Recruiting

Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.

for
Carcinoma, Hepatocellular, Hepatocellular Cancer,
Location: Orange CA, Irvine CA, Los Angeles CA, Pasadena CA,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07227012

Phase 1, Phase 2, Recruiting

E-Mindfulness Approaches for Living After Breast Cancer

for
Breast Cancer, Depression
Location: Orange CA, Irvine CA, Anaheim CA, Costa Mesa CA,
Sponsor: NRG Oncology

Sex: All

Age: 18 - 50

Code: NCT06748222

Phase 3, Recruiting

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

for
Prostate Cancer (Adenocarcinoma)
Location: Orange CA, Irvine CA, Anaheim CA, Newport Beach CA,
Sponsor: Canadian Cancer Trials Group

Sex: Male

Age: 18+

Code: NCT06592924

Phase 3, Recruiting

Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy

for
Recurrent Non-Muscle Invasive Bladder Carcinoma,
Location: Orange CA, Irvine CA, Phoenix AZ, Gilbert AZ, Reno NV,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT07000084

Phase 3, Recruiting

Response Adapted Neoadjuvant Therapy in Gastroesophageal Cancers (RANT-GC Trial)

for
Gastroesophageal Adenocarcinoma
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT05733689

Phase 1, Recruiting

A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Orange CA, Laguna Hills CA, San Diego CA, Palo Alto CA,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT06943872

Phase 3, Recruiting

Lung Cancer Screening of Family Members of Patients With Mutation-Driven Lung Cancer

for
Lung Cancer, Driver Mutation
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18 - 70+

Code: NCT07062172

Recruiting

A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer

for
Upper Urinary Tract Urothelial Carcinoma, Urothelial Carcinoma
Location: Orange CA, Bakersfield CA, Chandler AZ, Queen Creek AZ,
Sponsor: UroGen Pharma Ltd.

Sex: All

Age: 18+

Code: NCT06774131

Phase 3, Recruiting

Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies

for
Soft-tissue Sarcoma, Triple Negative Breast Cancer,
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT07064018

Phase 1, Phase 2, Recruiting

ICP-248 in Combination With Azacitidine for the Treatment in Patients With Myeloid Malignancies

for
Acute Myelogenous Leukemia, Myelodysplastic Syndromes (MDS)
Location: Orange CA, Milwaukee WI, Tampa FL, Chapel Hill NC,
Sponsor: Beijing InnoCare Pharma Tech Co., Ltd.

Sex: All

Age: 18+

Code: NCT06656494

Phase 1, Recruiting

Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer

for
Hormone-refractory Prostate Cancer
Location: Orange CA, Irvine CA, Duarte CA, Palo Alto CA,
Sponsor: Astellas Pharma Global Development, Inc.

Sex: Male

Age: 18+

Code: NCT05997615

Phase 1, Recruiting

Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma

for
Cutaneous Melanoma, Stage II
Location: Orange CA, Irvine CA, Los Angeles CA, Pasadena CA,
Sponsor: Melanoma and Skin Cancer Trials Limited

Sex: All

Age: 18+

Code: NCT03860883

Recruiting