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Paid Clinical Trials Orange County

Discover 3,617 paid clinical trials in Orange County, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Study of CTO1681 for the Prevention and Treatment of CRS in Patients Receiving CAR T-Cell Therapy

for
Cytokine Release Syndrome
Location: Orange CA, Seattle WA, Augusta GA, Pittsburgh PA,
Sponsor: CytoAgents, Inc.

Sex: All

Age: 18+

Code: NCT05905328

Phase 1, Phase 2, Recruiting

Adjuvant Sacituzumab Govitecan and Nivolumab in Muscle-Invasive Urothelial Carcinoma at High-Risk Recurrence

for
Urothelial Carcinoma, Muscle-invasive Bladder Cancer
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT06682728

Phase 2, Recruiting

Risk-ADAPTed Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation

for
Allogeneic Hematopoietic Stem Cell Transplantation,
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18 - 70

Code: NCT06028828

Phase 2, Recruiting

Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma

for
Retroperitoneal Sarcoma, Liposarcoma, Leiomyosarcoma
Location: Orange CA, Irvine CA, Duarte CA, La Jolla CA,
Sponsor: European Organisation for Research and Treatment of Cancer - EORTC

Sex: All

Age: 18+

Code: NCT04031677

Phase 3, Recruiting

Study to Investigate the Efficacy, Safety, and Tolerability of Topical HT-001 for the Treatment of Skin Toxicities Associated With Epidermal Growth Factor Receptor Inhibitors

for
Acneiform Eruption Due to Chemical, Xerosis Cutis, Paronychia
Location: Orange CA, Irvine CA, Houston TX, Canton OH, Miami FL,
Sponsor: Hoth Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05639933

Phase 2, Recruiting

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Study to Evaluate Maximum Tolerated Dose of Oral CB-03-10 With Dose Expansion Phase, in Advanced Solid Tumors

for
Advanced Refractory Solid Tumors,
Location: California City CA, Colorado Springs CO, Texas City TX,
Sponsor: Cosmo Technologies Ltd

Sex: All

Age: 18+

Code: NCT03863145

Early Phase 1, Recruiting

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

for
Non-small Cell Lung Cancer (NSCLC), Colorectal Cancer (CRC),
Location: Orange CA, Santa Monica CA, Salt Lake City UT,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT05379985

Phase 1, Phase 2, Recruiting

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

for
AML, AML With Mutated NPM1, Hematologic Malignancy, KMT2Ar,
Location: Orange CA, Los Angeles CA, Gilbert AZ, San Francisco CA,
Sponsor: Kura Oncology, Inc.

Sex: All

Age: 18+

Code: NCT06001788

Phase 1, Recruiting

Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

for
Diffuse Large B-Cell Lymphoma, Grade 3b Follicular Lymphoma,
Location: Orange CA, Irvine CA, Costa Mesa CA, Laguna Hills CA,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT05633615

Phase 2, Recruiting

Pembrolizumab Plus CA-4948 for the Treatment of Patients With Progressive Metastatic Urothelial Cancer Despite Prior Immunotherapy

for
Metastatic Urothelial Carcinoma,
Location: Orange CA, Irvine CA, Duarte CA, La Jolla CA, Dallas TX,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06439836

Phase 1, Recruiting

Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma

for
Classic Follicular Lymphoma,
Location: Orange CA, Irvine CA, Yorba Linda CA, Long Beach CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06337318

Phase 3, Recruiting

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

for
Acute Myeloid Leukemia,
Location: Orange CA, Irvine CA, Los Angeles CA, Fresno CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05564390

Phase 2, Recruiting

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Orange CA, Irvine CA, Anaheim CA, Costa Mesa CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04269902

Phase 3, Recruiting

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

for
Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8,
Location: Orange CA, Irvine CA, Torrance CA, Beverly Hills CA,
Sponsor: NRG Oncology

Sex: Male

Age: 18+

Code: NCT05946213

Phase 3, Recruiting

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

for
Metastatic Renal Cell Carcinoma,
Location: Orange CA, Irvine CA, Los Angeles CA, Beverly Hills CA,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT05327686

Phase 2, Recruiting

Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein β-Catenin, The SAPHIRE Trial

for
Advanced Hepatocellular Carcinoma,
Location: Orange CA, Irvine CA, Portland OR, Pittsburgh PA
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06811116

Phase 1, Phase 2, Recruiting

mpMRI Compared to Diagnostic TURBT in Patients With Suspected Muscle-Invasive Bladder Cancer

for
Urothelial Bladder Cancer, Muscle-Invasive Bladder Cancer
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT06335667

Recruiting

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial

for
Metastatic Colorectal Adenocarcinoma,
Location: Orange CA, Irvine CA, Beverly Hills CA, Los Angeles CA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT05673148

Phase 2, Recruiting

Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer

for
Refractory Differentiated Thyroid Gland Carcinoma
Location: Orange CA, Irvine CA, Burbank CA, Palo Alto CA, Napa CA,
Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All

Age: 18+

Code: NCT06475989

Phase 3, Recruiting

Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors

for
Metastatic Malignant Neoplasm in the Liver,
Location: Orange CA, Irvine CA, Huntington Beach CA,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT05040360

Phase 2, Recruiting