A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010).
A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)
A Study to Evaluate Safety and Efficacy of ALKS 7290 Compared With Placebo in Adult Participants With Attention Deficit Hyperactivity Disorder (ALKS 7290-201)
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A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)
Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia
Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)
To Establish the Safety and Effectiveness of the ALPFA GRAIL PFA System for Treating Symptomatic Benign Prostate Hyperplasia (BPH) Also Known as an Enlarged Prostate.
eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation
A Study to Identify and Characterize Patients With Type 2 Diabetes Mellitus for Possible Participation in Ongoing or Future Type 2 Diabetes Mellitus Clinical Studies
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis
Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer
Clinical research studies in The Villages
Memory and Alzheimer's research. The Villages and nearby Lady Lake are home to dedicated research sites such as Charter Research and K2 Medical Research, and many of their studies focus on memory loss, Alzheimer's disease, and related conditions such as Parkinson's disease. Our guide explains what Alzheimer's treatment looks like today.
Weight loss and diabetes. Studies of investigational medicines for obesity and type 2 diabetes also recruit in the area; see our weight loss clinical trials page.
Other conditions common after 60. Local studies also cover conditions such as fatty liver disease, COPD, osteoarthritis, and chronic pain, and some accept healthy volunteers.
Can you get paid for clinical trials in The Villages?
Some studies offer compensation for time and travel, and study related care is typically provided at no cost to participants. Compensation varies by trial and is always described during the informed consent process before you agree to anything. The ethics board that oversees each study, called an institutional review board, must approve both the amount and the payment schedule, and FDA guidance says payment should add up visit by visit rather than depend on finishing the whole study. In practice, people who leave a study early are usually paid for the visits they completed.
Our guide explains how much clinical trials pay and how payment is decided.
Does Medicare cover clinical trials?
Medicare covers the routine costs of qualifying clinical trials, such as the doctor visits and tests you would have whether or not you were in a study, and the care of complications that arise from taking part. It does not pay for the investigational item itself or for items the sponsor provides free to every participant, which usually includes the study medicine. Our guide to clinical trials for older adults explains Medicare coverage in more detail.
Do I have to stop my regular medicines to join a study?
Usually not, but some studies ask you to pause certain medicines for a set time, called a washout period, under the guidance of the study doctor. Never stop a prescribed medicine on your own to qualify for a study. Our guide explains how washout periods work.
How to join a clinical trial in The Villages
- Identify your trial. Use the filters on this page to narrow the list by condition or phase, or search a diagnosis such as Alzheimer's disease or type 2 diabetes.
- Check the location. Each study lists the sites where it recruits, so confirm it has a site in The Villages, Lady Lake, or another nearby town.
- Explore study details. Read the eligibility criteria and, where listed, the number of visits and how long the study lasts before applying.
- Complete the health profile. Click "See if you qualify" to begin the 5-step application. Have ready your diagnosis and when it was made, the medicines you take, and any recent test results.
- Submit the application. A clinical trial coordinator reviews it and contacts you to discuss next steps. Nothing is decided until informed consent, and participation is voluntary at every step.
Our guide to finding clinical trials near you covers each step in more detail.
Clinical trials near The Villages
Research sites in Lady Lake, Leesburg, and Ocala are within a short drive, and studies at these sites appear on this page. For larger hospital based research, see our pages for Orlando and Gainesville, each about an hour away, or browse all Florida clinical trials.