A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
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A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Sjogren's Disease
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
A Study to Compare TAK-881 and HYQVIA in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc Disease
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)
Clinical research studies in The Villages
Memory and Alzheimer's research. The Villages and nearby Lady Lake are home to dedicated research sites such as Charter Research and K2 Medical Research, and many of their studies focus on memory loss, Alzheimer's disease, and related conditions such as Parkinson's disease. Our guide explains what Alzheimer's treatment looks like today.
Weight loss and diabetes. Studies of investigational medicines for obesity and type 2 diabetes also recruit in the area; see our weight loss clinical trials page.
Other conditions common after 60. Local studies also cover conditions such as fatty liver disease, COPD, osteoarthritis, and chronic pain, and some accept healthy volunteers.
Can you get paid for clinical trials in The Villages?
Some studies offer compensation for time and travel, and study related care is typically provided at no cost to participants. Compensation varies by trial and is always described during the informed consent process before you agree to anything. The ethics board that oversees each study, called an institutional review board, must approve both the amount and the payment schedule, and FDA guidance says payment should add up visit by visit rather than depend on finishing the whole study. In practice, people who leave a study early are usually paid for the visits they completed.
Our guide explains how much clinical trials pay and how payment is decided.
Does Medicare cover clinical trials?
Medicare covers the routine costs of qualifying clinical trials, such as the doctor visits and tests you would have whether or not you were in a study, and the care of complications that arise from taking part. It does not pay for the investigational item itself or for items the sponsor provides free to every participant, which usually includes the study medicine. Our guide to clinical trials for older adults explains Medicare coverage in more detail.
Do I have to stop my regular medicines to join a study?
Usually not, but some studies ask you to pause certain medicines for a set time, called a washout period, under the guidance of the study doctor. Never stop a prescribed medicine on your own to qualify for a study. Our guide explains how washout periods work.
How to join a clinical trial in The Villages
- Identify your trial. Use the filters on this page to narrow the list by condition or phase, or search a diagnosis such as Alzheimer's disease or type 2 diabetes.
- Check the location. Each study lists the sites where it recruits, so confirm it has a site in The Villages, Lady Lake, or another nearby town.
- Explore study details. Read the eligibility criteria and, where listed, the number of visits and how long the study lasts before applying.
- Complete the health profile. Click "See if you qualify" to begin the 5-step application. Have ready your diagnosis and when it was made, the medicines you take, and any recent test results.
- Submit the application. A clinical trial coordinator reviews it and contacts you to discuss next steps. Nothing is decided until informed consent, and participation is voluntary at every step.
Our guide to finding clinical trials near you covers each step in more detail.
Clinical trials near The Villages
Research sites in Lady Lake, Leesburg, and Ocala are within a short drive, and studies at these sites appear on this page. For larger hospital based research, see our pages for Orlando and Gainesville, each about an hour away, or browse all Florida clinical trials.