Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy
Testing the Safety and Feasibility of Immunotherapy Drugs, Botensilimab and Balstilimab, Before Surgery for Clear Cell Renal Cell Carcinoma, NEO RoBOT Trial
A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer
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Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity
Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene
Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial
Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers
Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)
Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)
Combination Chemotherapy With or Without Peripheral Stem Cell Transplantation, Radiation Therapy, and/or Surgery in Treating Patients With Ewing's Sarcoma
Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial
A Trial to Investigate PALI-2108 Versus Placebo in Participants With Moderately to Severely Active Ulcerative Colitis
Clinical research studies in The Villages
Memory and Alzheimer's research. The Villages and nearby Lady Lake are home to dedicated research sites such as Charter Research and K2 Medical Research, and many of their studies focus on memory loss, Alzheimer's disease, and related conditions such as Parkinson's disease. Our guide explains what Alzheimer's treatment looks like today.
Weight loss and diabetes. Studies of investigational medicines for obesity and type 2 diabetes also recruit in the area; see our weight loss clinical trials page.
Other conditions common after 60. Local studies also cover conditions such as fatty liver disease, COPD, osteoarthritis, and chronic pain, and some accept healthy volunteers.
Can you get paid for clinical trials in The Villages?
Some studies offer compensation for time and travel, and study related care is typically provided at no cost to participants. Compensation varies by trial and is always described during the informed consent process before you agree to anything. The ethics board that oversees each study, called an institutional review board, must approve both the amount and the payment schedule, and FDA guidance says payment should add up visit by visit rather than depend on finishing the whole study. In practice, people who leave a study early are usually paid for the visits they completed.
Our guide explains how much clinical trials pay and how payment is decided.
Does Medicare cover clinical trials?
Medicare covers the routine costs of qualifying clinical trials, such as the doctor visits and tests you would have whether or not you were in a study, and the care of complications that arise from taking part. It does not pay for the investigational item itself or for items the sponsor provides free to every participant, which usually includes the study medicine. Our guide to clinical trials for older adults explains Medicare coverage in more detail.
Do I have to stop my regular medicines to join a study?
Usually not, but some studies ask you to pause certain medicines for a set time, called a washout period, under the guidance of the study doctor. Never stop a prescribed medicine on your own to qualify for a study. Our guide explains how washout periods work.
How to join a clinical trial in The Villages
- Identify your trial. Use the filters on this page to narrow the list by condition or phase, or search a diagnosis such as Alzheimer's disease or type 2 diabetes.
- Check the location. Each study lists the sites where it recruits, so confirm it has a site in The Villages, Lady Lake, or another nearby town.
- Explore study details. Read the eligibility criteria and, where listed, the number of visits and how long the study lasts before applying.
- Complete the health profile. Click "See if you qualify" to begin the 5-step application. Have ready your diagnosis and when it was made, the medicines you take, and any recent test results.
- Submit the application. A clinical trial coordinator reviews it and contacts you to discuss next steps. Nothing is decided until informed consent, and participation is voluntary at every step.
Our guide to finding clinical trials near you covers each step in more detail.
Clinical trials near The Villages
Research sites in Lady Lake, Leesburg, and Ocala are within a short drive, and studies at these sites appear on this page. For larger hospital based research, see our pages for Orlando and Gainesville, each about an hour away, or browse all Florida clinical trials.