Discover 65 paid clinical trials in Chicago, Illinois. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Sponsor:
University of Chicago
Location:
Code:
NCT06417762
Conditions
Misinformation
Influenza
COVID-19
Vaccine Hesitancy
Communication Research
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Accepted
Interventions
Science Communication Curriculum Cohort 1
Science communication curriculum Cohort 2
Science communication curriculum Cohort 3
Sponsor:
Puma Biotechnology, Inc.
Location:
Code:
NCT06369285
Conditions
Hormone Receptor Positive HER-2 Negative Breast Cancer
Metastatic Breast Cancer
Recurrent Breast Cancer
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Alisertib
Endocrine therapy
Sponsor:
Totus Medicines
Location:
Code:
NCT05683418
Conditions
Squamous Cell Carcinoma of Head and Neck
Endometrial Cancer
HR+/HER2-negative Breast Cancer
Bladder Cancer
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
TOS-358
Sponsor:
Relay Therapeutics, Inc.
Location:
Code:
NCT05216432
Conditions
PIK3CA Mutation
Solid Tumor, Adult
HER2-negative Breast Cancer
Breast Cancer
Metastatic Breast Cancer
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
RLY-2608
Fulvestrant
Palbociclib 125mg
Ribociclib 400mg
Ribociclib 600mg
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Sponsor:
University of Chicago
Location:
Code:
NCT05108870
Conditions
Human Papilloma Virus
HPV
HPV Positive Oropharyngeal Squamous Cell Carcinoma
Head and Neck Cancer
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
HB-201
HB-202
Carboplatin
Paclitaxel
Transoral Robotic Surgery
Sponsor:
Marina N Sharifi
Location:
Code:
NCT04762979
Conditions
Hormone Receptor Positive Breast Carcinoma
HER2-negative Breast Cancer
PIK3CA Mutant Metastatic Breast Cancer
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Alpelisib
Fulvestrant
Aromatase inhibitor
Sponsor:
University of Texas Southwestern Medical Center
Location:
Code:
NCT05029999
Conditions
HER2-negative Breast Cancer
Metastatic Breast Cancer
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
PLD Chemotherapy
CDX-1140
CDX-301
Sponsor:
University of Texas Southwestern Medical Center
Location:
Code:
NCT06084234
Conditions
Carcinoma, Hepatocellular
Liver Cancer
Liver Cirrhosis
Hepatitis B
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
GALAD
Liver Ultrasound with or without AFP
Sponsor:
QuantumLeap Healthcare Collaborative
Location:
Code:
NCT01042379
Conditions
Breast Neoplasms
Breast Cancer
Breast Tumors
Angiosarcoma
TNBC - Triple-Negative Breast Cancer
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Standard Therapy
AMG 386 with or without Trastuzumab
AMG 479 (Ganitumab) plus Metformin
MK-2206 with or without Trastuzumab
AMG 386 and Trastuzumab
Chicago is a vital city for clinical research, offering a robust healthcare network and renowned medical research institutions. Major facilities such as The University of Chicago Medicine, Northwestern Medicine, and Rush University Medical Center are at the forefront of pioneering research across various fields, including cancer, cardiovascular health, and neurological disorders.
The city of Chicago offers many advantages for individuals considering participation in clinical trials. With a diverse and vibrant population, researchers benefit from the variety of participants, improving the reliability and applicability of research findings across different demographics.
By opting to participate in a clinical trial in Chicago, individuals not only gain access to cutting-edge therapies and treatments but also contribute to vital medical research. This collaborative effort is supported by a robust clinical research infrastructure, ensuring participants receive high-quality care and attention while playing a crucial role in shaping the future of healthcare.
Chicago is a vibrant hub for clinical research, with its leading medical institutions conducting innovative studies across various medical conditions.
Chronic respiratory diseases like asthma and chronic obstructive pulmonary disease (COPD) are significant health issues in Chicago, prompting research efforts to improve management and treatment options.
Clinical trials conducted at institutions like Rush University Medical Center explore new inhalation therapies, biologics that target inflammatory pathways, and pulmonary rehabilitation techniques. These studies aim to enhance the quality of life for individuals suffering from respiratory conditions and reduce hospitalizations through innovative interventions and preventive measures.
With diabetes being a significant public health concern, Chicago has established itself as a leader in diabetes research. Institutions here conduct clinical trials that focus on both Type 1 and Type 2 diabetes, exploring new medications and interventions that aim to enhance blood sugar control. Recent trials in Chicago investigate novel insulin delivery systems, such as smart insulin pens and closed-loop systems, alongside medications that target various metabolic pathways.
Additionally, lifestyle interventions, including dietary and exercise programs, are examined to assess their effectiveness in managing and preventing diabetes-related complications, contributing to a holistic approach to diabetes care.
Chicago is recognized for its robust research in neurological disorders, particularly through institutions like The University of Chicago and Northwestern University. Clinical trials focus on progressive conditions such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis (MS).
Researchers are investigating novel pharmacological treatments, including drugs aimed at slowing disease progression and improving cognitive and motor functions. Innovative approaches, such as gene therapy and neuroprotective strategies, are also underway, providing hope for improved management of these debilitating conditions.
Clinical trials are also exploring the impact of lifestyle modifications, such as physical therapy and cognitive training, complement pharmacological research in enhancing the quality of life for patients.
With cardiovascular disease remaining a leading cause of morbidity and mortality in Chicago, institutions in the city are dedicated to innovative research in this area. Rush University Medical Center and Northwestern Medicine are prominent players, conducting clinical trials focused on conditions such as heart failure, coronary artery disease, and arrhythmias.
Trials often explore novel medical devices, such as transcatheter heart valves and left ventricular assist devices, alongside drug therapies designed to improve heart health. Studies on lifestyle interventions, including diet and exercise programs, also aim to provide comprehensive care strategies to reduce cardiovascular risk factors in diverse populations.
Chicago's mental health research is vital in addressing the growing prevalence of mental health disorders here. Institutions like Northwestern Medicine and The University of Chicago lead clinical trials focusing on conditions such as depression, anxiety, bipolar disorder, and schizophrenia. Researchers are exploring innovative treatment options, including novel antidepressants that target new pathways in the brain and psychotherapeutic techniques that complement pharmacological approaches.
Recent trials also investigate cutting-edge interventions like transcranial magnetic stimulation (TMS) and ketamine infusion therapy for treatment-resistant depression, aiming to provide alternative solutions for patients who have not responded to traditional therapies.
Chicago is at the forefront of cancer research, with major institutions like The University of Chicago Medicine, Northwestern Medicine, and Loyola University Medical Center conducting a wide range of clinical trials targeting multiple forms of cancer. These trials often focus on breast cancer, lung cancer, prostate cancer, and hematologic malignancies such as leukemia and lymphoma.
Researchers place efforts on advanced therapies, including immunotherapy, which harnesses the body’s immune system to fight cancer cells, and targeted therapies that attack specific cancer cell markers. For instance, CAR-T cell therapy is being explored as a groundbreaking treatment option for certain blood cancers, aiming to improve patient outcomes and reduce side effects compared to traditional treatments.
Chicago's contribution to infectious disease research is noteworthy, particularly in the realms of HIV/AIDS, COVID-19, and hepatitis C. Institutions here are at the forefront of clinical trials investigating new antiviral drugs, vaccine efficacy, and treatment protocols. For example, researchers are exploring long-acting injectable therapies for HIV prevention and treatment, which could revolutionize patient adherence and outcomes.
In Chicago, clinical trials are governed by a comprehensive framework of federal, state, and local regulations that ensure the safety and ethical treatment of participants. All clinical studies must comply with U.S. Food and Drug Administration (FDA) regulations, which set strict standards for conducting clinical research and require Institutional Review Board (IRB) approval before any trial can begin. The IRB is responsible for reviewing study protocols to ensure participant rights are protected, informed consent is obtained, and potential risks are minimized.
In the wider state, the Illinois Department of Public Health (IDPH) oversees the implementation of regulations related to medical research and human subjects protection. Additionally, Chicago's prominent research institutions have their own internal ethical review boards that adhere to these regulations, ensuring high standards of conduct in clinical trials. Compliance with Health Insurance Portability and Accountability Act (HIPAA) guidelines is also essential for protecting the privacy of participant health information throughout the research process.
Participating in a clinical trial provides individuals with an exceptional chance to access cutting-edge treatments and therapies before they become publicly available. Participants benefit from tailored care, as healthcare professionals closely oversee their health and progress throughout the study. This close monitoring helps manage any side effects effectively and enhances the potential advantages of the experimental therapies.
Involvement in clinical trials is crucial for advancing medical knowledge and innovation, often resulting in breakthroughs that improve the treatment and prevention of various illnesses. By enrolling in these studies, individuals not only access potentially life-altering therapies early but also play a vital role in the scientific community.
Interested in participating in clinical trials but worried about how long they might take? Check out our comprehensive guide for all the information you need to make an informed decision.
Enrolling in a clinical trial through our platform is a straightforward and user-friendly process. Here's how to get started: