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Paid Clinical Trials Indianapolis

Discover 874 paid clinical trials in Indianapolis, Indiana. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-101 in Participants With Myotonic Dystrophy Type 1

for
Myotonic Dystrophy Type 1 (DM1)
Location: Indianapolis IN, St Louis MO, Iowa City IA, Richmond VA,
Sponsor: Dyne Therapeutics

Sex: All

Age: 18 - 65

Code: NCT05481879

Phase1, Phase2, Recruiting
Active & Responsive

A Study to Assess How Well and Safely Elafibranor Works in Adult Participants With Primary Sclerosing Cholangitis

for
Primary Sclerosing Cholangitis
Location: Indianapolis IN, Johnson City TN, Baltimore MD,
Sponsor: Ipsen

Sex: All

Age: 18 - 70+

Code: NCT07387549

Phase3, Recruiting
Active & Responsive

Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

for
Alpha1-Antitrypsin Deficiency
Location: Indianapolis IN, Ann Arbor MI, St Louis MO, Novi MI,
Sponsor: Takeda

Sex: All

Age: 18 - 70+

Code: NCT05677971

Phase3, Recruiting
Active & Responsive

Exploring the Acute and Dynamic Relationships Between Movement and Pain in Older Adults With Musculoskeletal Pain

for
Older People, Pain
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 55 - 70+

Code: NCT06886906

Recruiting
Active & Responsive

Changes in Esophageal Distensibility With Proton Pump Inhibitors in Patients With Esophageal Eosinophilia: A Pilot Study

for
Eosinophilic Esophagitis
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 18 - 65

Code: NCT03312686

Recruiting

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Active & Responsive

Acoustic Waveform Respiratory Evaluation

for
Asthma, COPD, Cystic Fibrosis, Ciliary Motility Disorders,
Location: Indianapolis IN, Pittsburgh PA
Sponsor: Indiana University

Sex: All

Age: 8 - 70

Code: NCT06512064

Recruiting
Active & Responsive

Smart Pillows for Enhancing Sleep Quality

for
Snoring, Obstructive Sleep Apnea
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 50+

Code: NCT06594627

Recruiting
Active & Responsive

ASSESS ALL ALS Study

for
Amyotrophic Lateral Sclerosis
Location: Indianapolis IN, Chicago IL, Colombus OH, Ann Arbor MI,
Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All

Age: 18+

Code: NCT06578195

Recruiting
Active & Responsive

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

for
Treatment Resistant Depression
Location: Indianapolis IN, Chicago IL, Columbus OH, St Louis MO,
Sponsor: Abbott Medical Devices

Sex: All

Age: 22 - 70

Code: NCT06423430

Recruiting
Active & Responsive

Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network

for
Genetic Disease
Location: Indianapolis IN, St Louis MO, Nashville TN,
Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All

Age: 0 - 70+

Code: NCT02450851

Recruiting
Active & Responsive

Trial of Naltrexone/Bupropion for the Treatment of Methamphetamine Use Disorder

for
Methamphetamine-dependence, Methamphetamine Abuse
Location: Indianapolis IN, Memphis TN, Charlottesville VA,
Sponsor: National Institute on Drug Abuse (NIDA)

Sex: All

Age: 18 - 65

Code: NCT06233799

Phase3, Recruiting
Active & Responsive

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

for
Frontotemporal Lobar Degeneration (FTLD),
Location: Indianapolis IN, Chicago IL, Ann Arbor MI, St Louis MO,
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT04363684

Recruiting
Active & Responsive

DILIN - Prospective Study

for
Liver Diseases
Location: Indianapolis IN, Ann Arbor MI, Chapel Hill NC,
Sponsor: Duke University

Sex: All

Age: 2+

Code: NCT00345930

Recruiting
Active & Responsive

A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AG-181 in Subjects With Phenylketonuria

for
Phenylketonuria
Location: Indianapolis IN, Pittsburgh PA, Dallas TX
Sponsor: Agios Pharmaceuticals, Inc.

Sex: All

Age: 18 - 69

Code: NCT07241234

Phase1, Recruiting
Active & Responsive

A Study for the PanCystPro Assay in the Management of Pancreatic Cystic Lesions

for
Pancreatic Cystic Lesions
Location: Indianapolis IN, New Brunswick NJ, Boston MA
Sponsor: Amplified Sciences Inc

Sex: All

Age: 18+

Code: NCT06894329

Recruiting
Active & Responsive

A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes

for
Type 1 Diabetes, New Onset
Location: Indianapolis IN, Pittsburgh PA, Buffalo NY,
Sponsor: City of Hope Medical Center

Sex: All

Age: 9 - 20

Code: NCT07061574

Phase1, Phase2, Recruiting
Active & Responsive

Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men

for
Mitochondrial Energetics, Dietary Nitrate,
Location: Indianapolis IN
Sponsor: Indiana University

Sex: Male

Age: 18 - 44

Code: NCT07161973

Recruiting
Active & Responsive

Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)

for
Optic Neuritis, Myelitis, Myelitis, Transverse
Location: Indianapolis IN, Chicago IL, Evanston IL, Ann Arbor MI,
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07100990

Phase3, Recruiting
Active & Responsive

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

for
Glioma, Astrocytoma, Grade IV, IDH1-mutant Glioma,
Location: Indianapolis IN, Lexington KY, St Louis MO, Detroit MI,
Sponsor: Nuvation Bio Inc.

Sex: All

Age: 18+

Code: NCT05303519

Phase3, Recruiting
Active & Responsive

A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

for
Colorectal Cancer
Location: Indianapolis IN, Hinsdale IL, Columbus OH, St Louis MO,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT06562543

Recruiting