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Paid Clinical Trials Indianapolis

Discover 901 paid clinical trials in Indianapolis, Indiana. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

for
Psoriasis, Overweight or Obesity
Location: Indianapolis IN, Plainfield IN, Bowling Green KY,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT06857942

Recruiting
Active & Responsive

First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer

for
PIK3CA Mutation, Solid Tumor, Adult,
Location: Indianapolis IN, Chicago IL, Ann Arbor MI, St Louis MO,
Sponsor: Relay Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05216432

Phase 1, Recruiting
Active & Responsive

A Study of Tolododekin Alfa (ANK-101) in Combination With an Anti-PD-1/PD-L1 Antibody in Participants With Advanced Non-Small Cell Lung Cancer

for
Non Small Cell Lung Cancer
Location: Indianapolis IN, Peoria IL, Nashville TN, Buffalo NY,
Sponsor: Ankyra Therapeutics, Inc

Sex: All

Age: 18+

Code: NCT07027514

Phase 1, Recruiting
Active & Responsive

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

for
PIK3CA Mutation, HER2- Negative Breast Cancer,
Location: Indianapolis IN, Chicago IL, Ann Arbor MI, St Louis MO,
Sponsor: Relay Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06982521

Phase 3, Recruiting
Active & Responsive

A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)

for
Alzheimer Disease
Location: Indianapolis IN, Fort Wayne IN, Palos Hills IL,
Sponsor: Alpha Cognition, Inc

Sex: All

Age: 50+

Code: NCT07633470

Phase 4, Recruiting

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Active & Responsive

A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations

for
Parkinson Disease
Location: Indianapolis IN, Lexington KY, Columbus OH,
Sponsor: Appello Pharmaceuticals, Inc.

Sex: All

Age: 30 - 70+

Code: NCT07432958

Phase 2, Recruiting
Active & Responsive

BioPoly® Partial Resurfacing Knee Implant IDE

for
Knee Pain Chronic, Knee Osteoarthritis, Cartilage Damage,
Location: Indianapolis IN, Fort Wayne IN, Chesterfield MO,
Sponsor: BioPoly LLC

Sex: All

Age: 30 - 65

Code: NCT06915363

Recruiting
Active & Responsive

Antibiotic Device for Osteomyelitis of the Extremities Pivotal Trial - Genex With Gentamicin.

for
Osteomyelitis
Location: Indianapolis IN, Baltimore MD, Oradell NJ, San Diego CA
Sponsor: Biocomposites Ltd

Sex: All

Age: 18+

Code: NCT07270380

Recruiting
Active & Responsive

The Ailliance Post-Market Clinical Study

for
Spinal Deformity, Spinal Degenerative Disorder,
Location: Indianapolis IN, Carmel IN, Bloomington IN,
Sponsor: Medtronic Spinal and Biologics

Sex: All

Age: 18+

Code: NCT05856370

Recruiting
Active & ResponsiveNew

Knee Cartilage Repair Registry

for
Knee Injuries, Joint Surface Knee Lesions
Location: Indianapolis IN, DuBois PA, Washington D.C. DC,
Sponsor: Smith & Nephew, Inc.

Sex: All

Age: 18+

Code: NCT07786207

Recruiting
Active & Responsive

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

for
Diabetes Mellitus, Type 2, Hypertension,
Location: Avon IN, Greenfield IN, Muncie IN, Richmond IN,
Sponsor: Boehringer Ingelheim

Sex: All

Age: 18+

Code: NCT07064473

Phase 3, Recruiting
Active & Responsive

Study of GalaFLEX LITE™ Scaffold in Treatment of Capsular Contracture After Breast Implant Augmentation

for
Capsular Contracture Associated With Breast Implant,
Location: Indianapolis IN, Chicago IL, St Louis MO, Nashville TN,
Sponsor: C. R. Bard

Sex: Female

Age: 22 - 70

Code: NCT05945329

Recruiting
Active & Responsive

An Optimised GA Interventional Trial (Opti-GAIN) to Test if Treatment With CTx001 is Safe and Works for People With Geographic Atrophy (GA)

for
Geographic Atrophy Secondary to Age-related Macular Degeneration,
Location: Carmel IN, La Crosse WI, Dallas TX, Reno NV
Sponsor: Complement Therapeutics

Sex: All

Age: 55+

Code: NCT07392255

Phase 1, Phase 2, Recruiting
Active & Responsive

A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-004)

for
Diabetic Retinopathy, Macular Edema
Location: Carmel IN, Charleston WV, Knoxville TN, Johnson City TN,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07705555

Phase 3, Recruiting
Active & Responsive

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)

for
Macular Degeneration, Age-Related Macular Degeneration,
Location: Carmel IN, Cincinnati OH, Oak Park IL, Springfield IL,
Sponsor: EyeBiotech Ltd.

Sex: All

Age: 50+

Code: NCT07440225

Phase 2, Phase 3, Recruiting
Active & Responsive

A Study Comparing KB801 Verse Placebo in Patients With Stage 2 or 3 Neurotrophic Keratitis

for
Neurotrophic Keratitis
Location: Carmel IN, Town and Country MO, Minnetonka MN,
Sponsor: Krystal Biotech, Inc.

Sex: All

Age: 18+

Code: NCT06999733

Phase 1, Phase 2, Recruiting
Active & Responsive

RA-PRO PRAGMATIC TRIAL

for
Rheumatoid Arthritis
Location: Carmel IN, Liberty Township OH, Wheelersburg OH,
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 18+

Code: NCT04692493

Phase 3, Recruiting
Active & Responsive

An Open-Label Extension Study of ORKA-001 in Participants With Plaque Psoriasis

for
Plaque Psoriasis
Location: Plainfield IN, Mason OH, Rolling Meadows IL,
Sponsor: Oruka Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07449702

Phase 2, Recruiting
Active & Responsive

Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder

for
Major Depressive Disorder (MDD)
Location: Carmel IN, Cincinnati OH, Chicago IL, Saint Charles MO,
Sponsor: Vanda Pharmaceuticals

Sex: All

Age: 18 - 65

Code: NCT06830044

Phase 3, Recruiting
Active & Responsive

A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

for
Type 2 Diabetes
Location: Brownsburg IN, Dayton OH, Sarnia, Scottdale PA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 70+

Code: NCT06897475

Phase 2, Recruiting