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Paid Clinical Trials Des Moines

Discover 219 paid clinical trials in Des Moines, Iowa. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Featured

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer
Location: Des Moines IA, Iowa City IA, Lincoln NE,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06793215

Phase 3, Recruiting
Featured

Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)

for
Neovascular Age-related Macular Degeneration
Location: West Des Moines IA, Rochester MN, Lenexa KS, Edina MN,
Sponsor: AbbVie

Sex: All

Age: 50+

Code: NCT07007065

Phase 3, Recruiting
Featured

A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma

for
Lymphoma
Location: Waukee IA, Iowa City IA, Chesterfield MO, Ann Arbor MI,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06084936

Phase 3, Recruiting
Featured

Evaluate Optimization of CRS Profile for Glofit Monotherapy and Glofit+GemOx in R/R Aggressive B-NHL

for
Relapsed or Refractory Aggressive B-Cell Non-Hodgkins Lymphoma
Location: Waukee IA, Omaha NE, Swansea IL, Grand Rapids MI,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06806033

Phase 2, Recruiting
Featured

Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)

for
Migraine
Location: Ames IA, Papillion NE, Overland Park KS, Burnsville MN,
Sponsor: AbbVie

Sex: All

Age: 6 - 17

Code: NCT05125302

Phase 3, Recruiting

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Active & Responsive

Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease

for
Chronic Granulomatous Disease (CGD)
Location: Des Moines IA, Lincoln NE, Topeka KS, Jefferson City MO,
Sponsor: Ensoma

Sex: All

Age: 0+

Code: NCT06605378

Recruiting
Active & Responsive

Use of CA125 and Complementary Biomarkers for the Early Detection of Ovarian Cancer in Low Risk Women

for
Ovarian Cancer
Location: Des Moines IA, Minneapolis MN, Oklahoma City OK,
Sponsor: M.D. Anderson Cancer Center

Sex: Female

Age: 50 - 70+

Code: NCT00539162

Recruiting
Active & Responsive

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

for
Advanced Endometrial Carcinoma, Recurrent Endometrial Carcinoma
Location: Des Moines IA, Clive IA, Ankeny IA, Waukee IA,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT07198074

Phase 3, Recruiting
Active & Responsive

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

for
Advanced Esophageal Adenocarcinoma,
Location: Des Moines IA, Clive IA, Ankeny IA, Waukee IA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06203600

Phase 2, Phase 3, Recruiting
Active & Responsive

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

for
Recurrent Head and Neck Squamous Cell Carcinoma,
Location: Des Moines IA, Clive IA, Ankeny IA, Waukee IA, Omaha NE,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT04671667

Phase 2, Recruiting
Active & Responsive

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

for
Colorectal Cancer Stage II, Colorectal Cancer Stage III
Location: Des Moines IA, Clive IA, Pella IA, West Des Moines IA,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT07018869

Phase 3, Recruiting
Active & Responsive

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

for
Ampulla of Vater Carcinoma, Appendix Carcinoma,
Location: Des Moines IA, West Des Moines IA, Clive IA, Ankeny IA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT07283939

Recruiting
Active & Responsive

Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

for
Miscellaneous Neoplasm, Nos, Non-Neoplastic Condition, Nos
Location: Des Moines IA, Clive IA, Pella IA, West Des Moines IA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT07091617

Recruiting
Active & Responsive

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

for
Metastatic Dedifferentiated Liposarcoma,
Location: Clive IA, Des Moines IA, Ankeny IA, Waukee IA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06422806

Phase 3, Recruiting
Active & Responsive

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

for
Clinical Stage III Cutaneous Melanoma AJCC v8,
Location: Clive IA, Des Moines IA, Ankeny IA, Waukee IA, Ames IA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05136196

Phase 2, Recruiting
Active & Responsive

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

for
Plasma Cell Myeloma
Location: Des Moines IA, West Des Moines IA, Clive IA, Ankeny IA,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 0+

Code: NCT05561387

Phase 3, Recruiting
Active & Responsive

Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Des Moines IA, West Des Moines IA, Clive IA, Creston IA,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT05929768

Phase 3, Recruiting
Active & Responsive

A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

for
Metabolic Dysfunction-Associated Steatotic Liver Disease
Location: West Des Moines IA, Kansas City MO, Lenexa KS,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07165028

Phase 3, Recruiting
Active & ResponsiveNew

Research Study on How People With Type 2 Diabetes Tolerate Switching From Semaglutide to Cagrisema

for
Diabetes Mellitus, Type 2
Location: West Des Moines IA, Topeka KS, Skokie IL, Newton KS,
Sponsor: Novo Nordisk A/S

Sex: All

Age: 18+

Code: NCT07817251

Phase 3, Recruiting
Active & Responsive

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)

for
Obesity, Overweight, Diabetes Mellitus, Type 2
Location: West Des Moines IA, Kansas City MO, Lenexa KS,
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT07684144

Phase 3, Recruiting