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Paid Clinical Trials Des Moines

Discover 219 paid clinical trials in Des Moines, Iowa. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

for
Acute Leukemia of Ambiguous Lineage,
Location: Des Moines IA, Omaha NE, Kansas City MO, Sioux Falls SD,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0 - 1

Code: NCT06317662

Phase 2, Recruiting

A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

for
Acral Lentiginous Melanoma,
Location: Des Moines IA, West Des Moines IA, Ames IA, Boone IA,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT04511013

Phase 2, Recruiting

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

for
Triple Negative Breast Cancer
Location: Des Moines IA, Iowa City IA, Omaha NE, Rochester MN,
Sponsor: Gilead Sciences

Sex: All

Age: 18+

Code: NCT05633654

Phase 3, Recruiting

Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)

for
Myelodysplastic Syndrome
Location: Des Moines IA, Clive IA, Pella IA, Ankeny IA, Waukee IA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06577441

Phase 2, Recruiting

Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

for
AL Amyloidosis
Location: Des Moines IA, Clive IA, Ankeny IA, Waukee IA, Omaha NE,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT06022939

Phase 3, Recruiting

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Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

for
Lung Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8,
Location: Des Moines IA, Clive IA, Ankeny IA, Waukee IA, Ames IA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06498635

Phase 3, Recruiting

Testing Lutetium Lu 177 Dotatate in Patients With Somatostatin Receptor Positive Advanced Bronchial Neuroendocrine Tumors

for
Advanced Lung Neuroendocrine Tumor,
Location: Des Moines IA, Ankeny IA, Rochester MN, St Louis MO,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04665739

Phase 2, Recruiting

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

for
Non-Muscle Invasive Bladder Urothelial Carcinoma,
Location: Des Moines IA, Clive IA, Pella IA, West Des Moines IA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06770582

Phase 2, Recruiting

Comparing Retreatment of 177Lu-DOTATATE PRRT Versus the Usual Treatment in Patients With Metastatic Unresectable Gastroenteropancreatic Neuroendocrine Tumors, NET RETREAT Trial

for
Metastatic Digestive System Neuroendocrine Tumor G1,
Location: Des Moines IA, Clive IA, Ankeny IA, Waukee IA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05773274

Phase 2, Recruiting

Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the Lung

for
Advanced Extrapulmonary Neuroendocrine Carcinoma,
Location: Des Moines IA, Clive IA, West Des Moines IA, Ankeny IA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05058651

Phase 2, Phase 3, Recruiting

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma

for
Glioblastoma, IDH-Wildtype, MGMT-Unmethylated Glioblastoma
Location: Des Moines IA, Clive IA, Pella IA, Ankeny IA, Waukee IA,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT07452458

Phase 3, Recruiting

Testing the Addition of Duvelisib or CC-486 to the Usual Treatment for Peripheral T-Cell Lymphoma

for
Angioimmunoblastic T-cell Lymphoma,
Location: Des Moines IA, Ankeny IA, Waukee IA, Iowa City IA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT04803201

Phase 2, Recruiting

Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer

for
Astrocytoma, IDH-Mutant, Grade 3
Location: Des Moines IA, Clive IA, Pella IA, Ankeny IA, Waukee IA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 12+

Code: NCT07215910

Phase 3, Recruiting

Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

for
Metastatic Castration-Resistant Prostate Carcinoma,
Location: Des Moines IA, Ames IA, Marshalltown IA, Fort Dodge IA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: Male

Age: 18+

Code: NCT07200830

Phase 3, Recruiting

Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial

for
Anatomic Stage II Breast Cancer AJCC v8,
Location: Des Moines IA, Clive IA, Ankeny IA, Waukee IA, Ames IA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07391774

Phase 3, Recruiting

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study

for
Muscle Invasive Bladder Urothelial Carcinoma,
Location: Des Moines IA, Clive IA, West Des Moines IA, Ankeny IA,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT07097142

Phase 3, Recruiting

Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial

for
Advanced Hepatocellular Carcinoma,
Location: Des Moines IA, Clive IA, West Des Moines IA, Ankeny IA,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT07166406

Phase 3, Recruiting

Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer

for
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Des Moines IA, Clive IA, Ankeny IA, Waukee IA, Omaha NE,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07195734

Phase 2, Recruiting

Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

for
Non-small Cell Lung Cancer
Location: Des Moines IA, Clive IA, Pella IA, Ankeny IA, Waukee IA,
Sponsor: Canadian Cancer Trials Group

Sex: All

Age: 18+

Code: NCT06686771

Phase 3, Recruiting

Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical Cancer

for
Locally Advanced Adrenal Cortical Carcinoma,
Location: Des Moines IA, Clive IA, Ankeny IA, Waukee IA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 12+

Code: NCT06900595

Phase 2, Recruiting