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Paid Clinical Trials Des Moines

Discover 219 paid clinical trials in Des Moines, Iowa. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Waukee IA, Rochester MN, Westwood KS, La Crosse WI,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT06973187

Phase 3, Recruiting

A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)

for
Metastatic Castration-resistant Prostatic Neoplasms
Location: Waukee IA, Iowa City IA, Omaha NE, Minneapolis MN,
Sponsor: Janssen Research & Development, LLC

Sex: Male

Age: 18+

Code: NCT07164443

Phase 3, Recruiting

A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Waukee IA, Iowa City IA, Omaha NE, Rochester MN,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT06943872

Phase 3, Recruiting

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

for
Lymphoma, Large B-Cell, Diffuse
Location: Waukee IA, Iowa City IA, Omaha NE, Lincoln NE,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06890884

Phase 2, Recruiting

A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Waukee IA, Germantown TN, Edgewood KY, The Woodlands TX,
Sponsor: Loxo Oncology, Inc.

Sex: All

Age: 18+

Code: NCT06588478

Phase 2, Recruiting

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Outcomes Following Combined Adductoplasty™ and Lapiplasty® (MTA3D)

for
Metatarsus Adductus, Hallux Valgus
Location: Ankeny IA, Jefferson City MO, Greeley CO, Keller TX,
Sponsor: Treace Medical Concepts, Inc.

Sex: All

Age: 14 - 65

Code: NCT05587569

Recruiting

A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Waukee IA, Iowa City IA, Kansas City MO,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06136559

Phase 3, Recruiting

Evaluation of the Walk With Ease Program for Fall Prevention

for
Exercise, Frailty, Arthritis, Accidental Falls
Location: Ames IA
Sponsor: Iowa State University

Sex: All

Age: 65+

Code: NCT05693025

Phase 1, Phase 2, Recruiting

The Blossom Project: "BlossomUP" Methods to Decrease Sedentary Time in Pregnancy

for
Sedentary Lifestyle, Diabetes Mellitus, Gestational
Location: Ames IA
Sponsor: Iowa State University

Sex: Female

Age: 18 - 45

Code: NCT02909725

Recruiting

Cybersickness Prevention and Mitigation in Virtual Reality for Healthy Volunteers

for
Healthy Volunteers, Virtual Reality
Location: Ames IA, Bethesda MD
Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All

Age: 18 - 60

Code: NCT06552754

Recruiting

A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

for
Carcinoma, Non-Small-Cell Lung
Location: Ames IA, Rochester MN, Kansas City MO, Fairway KS,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06667076

Phase 2, Recruiting

A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older

for
Clostridoides Difficile Associated Disease
Location: Ames IA, Omaha NE, Sioux City IA, Grand Island NE,
Sponsor: Pfizer

Sex: All

Age: 65+

Code: NCT07282665

Phase 3, Recruiting

A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer

for
HER2-positive Breast Cancer, Breast Cancer
Location: Ames IA, Omaha NE, Lincoln NE, Madison WI, Nashville TN,
Sponsor: Jazz Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07102381

Phase 2, Recruiting

A Phase 3 Study of Revaccination in Subsequent Pregnancies With Bivalent RSV Vaccine and Duration of Protection of a Single Dose

for
RSV Infection
Location: Ames IA, Kansas City KS, Norfolk NE, Grand Island NE,
Sponsor: Pfizer

Sex: All

Age: 0+

Code: NCT06866405

Phase 3, Recruiting

A Study to Investigate Abdominal Symptoms With Camlipixant Compared With Placebo in Adults With Irritable Bowel Syndrome - Diarrhea (IBS-D) and Irritable Bowel Syndrome - Mixed (IBS-M)

for
Irritable Bowel Syndrome
Location: Ames IA, Morton IL, Hazelwood MO, Oak Lawn IL, Tulsa OK,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18 - 70+

Code: NCT07519395

Phase 2, Recruiting

Testing the Combination of Venetoclax and Rituximab, in Comparison to the Usual Treatment (Ibrutinib Plus Rituximab or Zanubrutinib Alone) for Waldenstrom's Macroglobulinemia/Lymphoplasmacytic Lymphoma

for
Lymphoplasmacytic Lymphoma, Waldenstrom Macroglobulinemia
Location: Ames IA, Marshalltown IA, Fort Dodge IA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04840602

Phase 2, Recruiting

A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

for
Locally Advanced Urothelial Carcinoma,
Location: Ames IA, Marshalltown IA, Fort Dodge IA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06524544

Phase 3, Recruiting

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

for
Castration-Sensitive Prostate Carcinoma,
Location: Ames IA, Marshalltown IA, Fort Dodge IA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: Male

Age: 18+

Code: NCT06931340

Phase 3, Recruiting

Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial

for
Lung Non-Small Cell Carcinoma
Location: Ames IA, Marshalltown IA, Fort Dodge IA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07388524

Phase 3, Recruiting

High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer

for
Head and Neck Squamous Cell Carcinoma,
Location: Ames IA, Marshalltown IA, Fort Dodge IA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT06992427

Phase 3, Recruiting