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Paid Clinical Trials Lexington

Discover 419 paid clinical trials in Lexington, Kentucky. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

for
Down Syndrome, Recurrent B Acute Lymphoblastic Leukemia
Location: Lexington KY, Louisville KY, Cincinnati OH, Dayton OH,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 1 - 30

Code: NCT04546399

Phase2, Recruiting

A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

for
Leukemia, Myeloid, Acute
Location: Lexington KY, Louisville KY, Cincinnati OH,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06852222

Phase3, Recruiting

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

for
Malignant Glioma
Location: Lexington KY, Louisville KY, Cincinnati OH, Dayton OH,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 1 - 21

Code: NCT05099003

Phase1, Phase2, Recruiting

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

for
B Acute Lymphoblastic Leukemia
Location: Lexington KY, Louisville KY, Cincinnati OH, Dayton OH,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 1 - 46

Code: NCT06124157

Phase2, Recruiting

Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors

for
Pancreatic Neuroendocrine Tumor (pNET),
Location: Lexington KY, Knoxville TN, Columbus OH, Nashville TN,
Sponsor: Exelixis

Sex: All

Age: 18+

Code: NCT06943755

Phase2, Phase3, Recruiting

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A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis

for
Recurrent Langerhans Cell Histiocytosis,
Location: Lexington KY, Dayton OH, Knoxville TN, Indianapolis IN,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0 - 22

Code: NCT05828069

Phase2, Recruiting

Lanreotide Versus Placebo Before Surgery to Prevent a Surgical Complication Called a Pancreatic Fistula

for
Pancreatic Carcinoma, Pancreatic Neoplasm
Location: Lexington KY, Sainte Genevieve MO, Chicago IL,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT06807437

Phase3, Recruiting

A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Lexington KY, Knoxville TN, Indianapolis IN,
Sponsor: Children's Oncology Group

Sex: All

Age: 15 - 20

Code: NCT06410209

Phase2, Recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

for
Advanced Malignant Solid Neoplasm,
Location: Lexington KY, Cincinnati OH, Portsmouth OH, Franklin OH,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0+

Code: NCT05564377

Phase2, Recruiting

Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers

for
Metastatic Salivary Gland Carcinoma,
Location: Lexington KY, Cincinnati OH, West Chester OH,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT05408845

Phase2, Recruiting

Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

for
Metastatic Clear Cell Renal Cell Carcinoma,
Location: Lexington KY, Cincinnati OH, West Chester OH,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT04510597

Phase3, Recruiting

Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)

for
Acute Myeloid Leukemia,
Location: Lexington KY, Louisville KY, Knoxville TN,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 59

Code: NCT05554406

Phase2, Recruiting

A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)

for
Chronic Graft-Versus-Host Disease (cGVHD)
Location: Lexington KY, Cincinnati OH, Columbus OH, Nashville TN,
Sponsor: Deciphera Pharmaceuticals, LLC

Sex: All

Age: 18+

Code: NCT06619561

Phase2, Recruiting

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

for
Acute Myeloid Leukemia
Location: Lexington KY, Louisville KY, Knoxville TN, Effingham IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 59

Code: NCT05554393

Phase2, Recruiting

Quaratusugene Ozeplasmid (Reqorsa) and Osimertinib in Patients With Advanced Lung Cancer Who Progressed on Osimertinib

for
Carcinoma, Non-Small Cell Lung
Location: Lexington KY, Urbana IL, Canton OH, Fairfax VA,
Sponsor: Genprex, Inc.

Sex: All

Age: 18+

Code: NCT04486833

Phase1, Phase2, Recruiting

Evaluating Genomic Testing in Human Cancer & Outcomes of Targeted Therapies

for
Cancer
Location: Lexington KY
Sponsor: Rachel Miller

Sex: All

Age: 18+

Code: NCT03089554

Phase2, Recruiting

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

for
Recurrent Lung Non-Small Cell Carcinoma,
Location: Lexington KY, Franklin OH, Centerville OH,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 0+

Code: NCT06031688

Phase2, Recruiting

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

for
Low Grade Astrocytoma, Low Grade Glioma,
Location: Lexington KY, Louisville KY, Cincinnati OH, Dayton OH,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 2 - 21

Code: NCT04166409

Phase3, Recruiting

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

for
B Acute Lymphoblastic Leukemia, B Lymphoblastic Lymphoma,
Location: Lexington KY, Louisville KY, Cincinnati OH, Dayton OH,
Sponsor: Children's Oncology Group

Sex: All

Age: 1 - 25

Code: NCT03959085

Phase3, Recruiting

Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

for
Embryonal Rhabdomyosarcoma,
Location: Lexington KY, Louisville KY, Cincinnati OH, Dayton OH,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 21

Code: NCT05304585

Phase3, Recruiting