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Paid Clinical Trials Lexington

Discover 419 paid clinical trials in Lexington, Kentucky. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema

for
Emphysema, Pulmonary, Emphysema or COPD
Location: Lexington KY, Knoxville TN, Pittsburgh PA, Chicago IL,
Sponsor: Pulmonx Corporation

Sex: All

Age: 40 - 70+

Code: NCT06035120

Recruiting
Active & Responsive

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

for
Heart Failure, Heart Diseases, Cardiovascular Diseases,
Location: Lexington KY, Louisville KY, Cincinnati OH,
Sponsor: Abbott Medical Devices

Sex: All

Age: 18+

Code: NCT06526195

Recruiting
Active & Responsive

The ME&MG Digital Solution for Autonomous Assessment of Myasthenia Gravis

for
Myasthenia Gravis
Location: Lexington KY, Indianapolis IN, Nashville TN, Durham NC,
Sponsor: Ad scientiam

Sex: All

Age: 18+

Code: NCT05564936

Recruiting
Active & Responsive

Autologous suraL nervE Grafting to the Substantia nigrA in Patients With Synuclienopathies

for
Multiple System Atrophy, Parkinsons Disease
Location: Lexington KY
Sponsor: Craig van Horne, MD, PhD

Sex: All

Age: 40 - 70+

Code: NCT06683365

Phase1, Recruiting
Active & Responsive

A Study to Evaluate Feasibility, Safety, and Clinical Responses of Implanting Autologous Peripheral Nerve Tissue Into the Brain for Non-motor or Motor Symptoms in Patients With Parkinson's Disease Undergoing DBS Surgery

for
Parkinson's Disease
Location: Lexington KY
Sponsor: Craig van Horne, MD, PhD

Sex: All

Age: 45 - 70+

Code: NCT06683378

Phase1, Recruiting

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Active & Responsive

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

for
Glioma, Astrocytoma, Grade IV, IDH1-mutant Glioma,
Location: Lexington KY, Indianapolis IN, Nashville TN,
Sponsor: Nuvation Bio Inc.

Sex: All

Age: 18+

Code: NCT05303519

Phase3, Recruiting
Active & Responsive

A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo™ Aspiration System (STRIDE II)

for
Lower Extremity Acute Limb Ischemia, LE ALI
Location: Lexington KY, Cincinnati OH, Indianapolis IN,
Sponsor: Penumbra Inc.

Sex: All

Age: 18+

Code: NCT06747117

Recruiting
Active & Responsive

CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients With Relapsed/Refractory Multiple Myeloma

for
Relapsed/Refractory Multiple Myeloma
Location: Lexington KY, Cincinnati OH, Nashville TN, Charlotte NC,
Sponsor: Caribou Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT05722418

Phase1, Recruiting
Active & Responsive

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

for
Advanced Endometrial Carcinoma, Recurrent Endometrial Carcinoma
Location: Lexington KY, Columbus OH, Athens OH, Indianapolis IN,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT07198074

Phase3, Recruiting
Active & Responsive

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

for
Recurrent Head and Neck Squamous Cell Carcinoma,
Location: Lexington KY, Louisville KY, Franklin OH,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT04671667

Phase2, Recruiting
Active & Responsive

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

for
Autoimmune Disease, Crohn Disease, Dermatomyositis,
Location: Lexington KY, Columbus OH, Pittsburgh PA, St Louis MO,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT03816345

Phase1, Recruiting
Active & Responsive

Trial of the Efficacy and Safety of Short and Long Course Radiation Therapy With/Without BMX-001

for
Rectal Cancer
Location: Lexington KY, Omaha NE, San Antonio TX
Sponsor: University of Nebraska

Sex: All

Age: 18+

Code: NCT05254327

Phase2, Recruiting
Active & Responsive

Cs-131LDR Brachytherapy for Organ-Preserving Irradiation for Recurrent Cervical and Endometrial Cancer

for
Gynecologic Cancer
Location: Lexington KY
Sponsor: Denise Fabian

Sex: Female

Age: 18+

Code: NCT07631572

Recruiting
Active & Responsive

Comparing Radiation Plus Cetuximab to Radiation Plus Chemotherapy in People With Head and Neck Cancer Who Cannot Receive Cisplatin

for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Lexington KY, Louisville KY, Cincinnati OH,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT07441681

Phase3, Recruiting
Active & Responsive

Optimizing Ancillary Therapies With Immune Checkpoint Inhibitors for Solid Tumors (OAT ICI)

for
Solid Tumors
Location: Lexington KY
Sponsor: Val Adams

Sex: All

Age: 18 - 70+

Code: NCT07661459

Phase2, Recruiting
Active & Responsive

Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

for
Extensive Stage Lung Small Cell Carcinoma,
Location: Lexington KY, Cincinnati OH, West Chester OH,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06287775

Phase1, Phase2, Recruiting
Active & Responsive

Blood Flow Restriction Training After Patellar INStability

for
Patellar Dislocation, Knee Injuries, Leg Injury,
Location: Lexington KY, Foxborough MA
Sponsor: Caitlin Conley

Sex: All

Age: 14 - 40

Code: NCT04554212

Recruiting
Active & Responsive

Shared Decision Making to Treat Or Prevent (STOP) HIV in Criminal Legal Involved Populations (R33)

for
Substance Use Disorders
Location: Lexington KY, New Haven CT, Dallas TX, Fort Worth TX
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT07223398

Recruiting
Active & Responsive

A Pragmatic Clinical Trial of the WE BEAT Well-Being Education Program in Adolescent Congenital Heart Disease: WE BEAT CHD Study

for
Patient-Reported Outcome Measures (PROMs), Pragmatic Trial,
Location: Lexington KY, Cincinnati OH, Atlanta GA, Pittsburgh PA,
Sponsor: Carelon Research

Sex: All

Age: 12 - 17

Code: NCT07525843

Recruiting
Active & Responsive

A Study of MZE782 in Adults With PKU

for
Phenylketonuria (PKU)
Location: Lexington KY, Indianapolis IN, Memphis TN,
Sponsor: Maze Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT07694440

Phase2, Recruiting