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Paid Clinical Trials Lexington

Discover 419 paid clinical trials in Lexington, Kentucky. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC

for
Non-squamous Non-small Cell Lung Cancer
Location: Lexington KY, Louisville KY, Nashville TN,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06627647

Phase3, Recruiting

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

for
Heart Failure
Location: Lexington KY, Louisville KY, Cincinnati OH, Dayton OH,
Sponsor: AstraZeneca

Sex: All

Age: 40+

Code: NCT06677060

Phase3, Recruiting

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

for
COPD (Chronic Obstructive Pulmonary Disease)
Location: Lexington KY, Blue Ash OH, Columbus OH, Marion OH,
Sponsor: AstraZeneca

Sex: All

Age: 40 - 70+

Code: NCT06283966

Phase3, Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MBX 4291 in Adult Participants With Obesity

for
Obesity
Location: Lexington KY, Knoxville TN, Kansas City MO, Doral FL
Sponsor: MBX Biosciences

Sex: All

Age: 18 - 65

Code: NCT07142707

Phase1, Recruiting

Imeroprubart in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

for
Chronic Inflammatory Demyelinating Polyneuropathy
Location: Nicholasville KY, Charlotte NC, Chicago IL, Detroit MI,
Sponsor: Immunovant Sciences GmbH

Sex: All

Age: 18+

Code: NCT07032662

Phase2, Recruiting

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Study of KITE-363 or KITE-753 in Participants With Relapsed and/or Refractory B-cell Lymphoma

for
Relapsed and/or Refractory B-cell Lymphoma
Location: Shelbyville KY, Columbus OH, Nashville TN, Atlanta GA,
Sponsor: Kite, A Gilead Company

Sex: All

Age: 18+

Code: NCT04989803

Phase1, Phase2, Recruiting

Impact of Direct Current Electrical Stimulation on Treatment of Lumbosacral Radiculopathy

for
Radiculopathy Lumbar, Radiculopathy Sacral,
Location: Bardstown KY, Shepherdsville KY, Portland IN,
Sponsor: NeuFit - Neurological Fitness and Education

Sex: All

Age: 18+

Code: NCT06421558

Recruiting

A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age

for
Chickenpox
Location: Bardstown KY, Louisville KY, Dayton OH, Greenville SC,
Sponsor: GlaxoSmithKline

Sex: All

Age: 1

Code: NCT06740630

Phase3, Recruiting

Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Children With ADHD

for
Attention-Deficit/Hyperactivity Disorder
Location: Bardstown KY, Cincinnati OH, West Chester OH,
Sponsor: Supernus Pharmaceuticals, Inc.

Sex: All

Age: 4 - 5

Code: NCT04781140

Recruiting

A Study to Learn About the Safety of an Expanded Pneumococcal Vaccine in Healthy Infants

for
Pneumococcal Disease
Location: Bardstown KY, Simpsonville SC, South Euclid OH,
Sponsor: Pfizer

Sex: All

Age: 0

Code: NCT07573462

Phase3, Recruiting

Study to Learn About Safety, Tolerability, and Immune Response of a Catch-up Pneumococcal Vaccine in Children and Adolescents

for
Pneumococcal Disease
Location: Bardstown KY, Cincinnati OH, Dayton OH, Tullahoma TN,
Sponsor: Pfizer

Sex: All

Age: 1 - 17

Code: NCT07660198

Phase3, Recruiting

Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)

for
Myelodysplastic Syndrome
Location: Louisville KY, Knoxville TN, Columbus OH, Danville IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06577441

Phase2, Recruiting

Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer

for
Astrocytoma, IDH-Mutant, Grade 3
Location: Louisville KY, Cincinnati OH, West Chester OH,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 12+

Code: NCT07215910

Phase3, Recruiting

Testing Whether High Dose Chemotherapy and Infusion of the Patients' Own Stem Cells Improves Survival in Patients With Peripheral T-cell Lymphoma Who Achieved a Complete Response at the End of the Initial Chemotherapy

for
Anaplastic Large Cell Lymphoma, ALK-Negative,
Location: Louisville KY, Indianapolis IN, Columbus OH, Athens OH,
Sponsor: Eastern Cooperative Oncology Group

Sex: All

Age: 18 - 70+

Code: NCT06724237

Phase3, Recruiting

Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)

for
Acute Myeloid Leukemia
Location: Louisville KY, Knoxville TN, Easley SC, Seneca SC,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06672146

Phase2, Recruiting

A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

for
Locally Advanced Urothelial Carcinoma,
Location: Louisville KY, Columbus OH, Charleston WV,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06524544

Phase3, Recruiting

ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Louisville KY, Cincinnati OH, West Chester OH,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT06876714

Phase3, Recruiting

Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Leukemia
Location: Louisville KY, Columbus OH, Athens OH, Pickerington OH,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 65+

Code: NCT07321652

Phase3, Recruiting

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

for
Endometrial Adenocarcinoma,
Location: Louisville KY, Centerville OH, Indianapolis IN,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT05112601

Phase2, Recruiting

Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma

for
Retroperitoneal Sarcoma, Liposarcoma, Leiomyosarcoma
Location: Louisville KY, Knoxville TN, Columbus OH, Nashville TN,
Sponsor: European Organisation for Research and Treatment of Cancer - EORTC

Sex: All

Age: 18+

Code: NCT04031677

Phase3, Recruiting