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Paid Clinical Trials Boston

Discover 3,070 paid clinical trials in Boston, Massachusetts. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema

for
Emphysema, Pulmonary, Emphysema or COPD
Location: Boston MA, Hartford CT, Philadelphia PA,
Sponsor: Pulmonx Corporation

Sex: All

Age: 40 - 70+

Code: NCT06035120

Recruiting
Active & Responsive

Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services

for
Schizophrenia Spectrum and Other Psychotic Disorders,
Location: Boston MA, Belmont MA, Hartford CT, Chicago IL,
Sponsor: Beth Israel Deaconess Medical Center

Sex: All

Age: 18 - 40

Code: NCT06740383

Recruiting
Active & Responsive

Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))

for
Mesial Temporal Lobe Epilepsy
Location: Boston MA, Lebanon NH, Great Neck NY, New York NY,
Sponsor: Neurona Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT05135091

Phase3, Recruiting
Active & Responsive

A Study for the PanCystPro Assay in the Management of Pancreatic Cystic Lesions

for
Pancreatic Cystic Lesions
Location: Boston MA, New Brunswick NJ, Indianapolis IN
Sponsor: Amplified Sciences Inc

Sex: All

Age: 18+

Code: NCT06894329

Recruiting
Active & Responsive

A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations

for
Parkinson Disease
Location: Boston MA, New York NY, Durham NC, Farmington Hills MI,
Sponsor: Appello Pharmaceuticals, Inc.

Sex: All

Age: 30 - 70+

Code: NCT07432958

Phase2, Recruiting

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Active & Responsive

A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease

for
Huntington Disease
Location: Boston MA, Farmington CT, Albany NY, Burlington VT,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 21 - 70

Code: NCT07326709

Phase3, Recruiting
Active & Responsive

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

for
Prostate Cancer, Prostatic Neoplasms
Location: Boston MA, New Haven CT, West Haven CT, New York NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: Male

Age: 18+

Code: NCT06925737

Phase3, Recruiting
Active & Responsive

A Study of TAK-411 in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

for
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP),
Location: Boston MA, Philadelphia PA, Atlanta GA, Jacksonville FL,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT06798012

Phase2, Recruiting
Active & Responsive

Cognitive Control to Boost Physical Activity Adherence

for
Physical Inactivity
Location: Boston MA, Iowa City IA
Sponsor: University of Iowa

Sex: All

Age: 40 - 65

Code: NCT06338774

Recruiting
Active & Responsive

Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies

for
Congenital Fibrosis of Extraocular Muscles,
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 0+

Code: NCT03059420

Recruiting
Active & Responsive

Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study

for
Cystic Fibrosis, Cystic Fibrosis Pulmonary Exacerbation
Location: Boston MA, Worcester MA, Portland ME, Lebanon NH,
Sponsor: Chris Goss

Sex: All

Age: 6+

Code: NCT05548283

Recruiting
Active & Responsive

THE GUIDE: Transforming Health for Young Adults Using Interventions to Drive Engagement

for
Transgender Persons, Health Services for Transgender Persons,
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 18 - 29

Code: NCT06177600

Recruiting
Active & ResponsiveNew

Outcomes of Neurosurgical Tone Management

for
Spastic/Dystonic Quadriplegia, Cerebral Palsy (CP)
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 6 - 25

Code: NCT07817745

Recruiting
Active & Responsive

Molecular Genetic Mechanisms of Infantile Epilepsies and the Impact of Genetic Diagnosis

for
Neonatal Epilepsy, Infantile Epilepsy
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 0+

Code: NCT06701084

Recruiting
Active & Responsive

A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants, Adolescents and Adults With Hearing Loss Due to Otoferlin Mutations

for
Congenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF),
Location: Boston MA, New York NY, Cincinnati OH, Milwaukee WI,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 0+

Code: NCT05788536

Phase1, Phase2, Recruiting
Active & Responsive

Advancing Transplantation Outcomes in Children

for
Kidney Transplant
Location: Boston MA, Philadelphia PA, Wilmington DE, Baltimore MD,
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 13 - 20

Code: NCT06055608

Phase2, Recruiting
Active & Responsive

Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia

for
Hereditary Spastic Paraplegia, SPG47, SPG50, SPG51, SPG52,
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 0 - 30

Code: NCT04712812

Recruiting
Active & Responsive

Allogeneic Valve Transplantation

for
Valve Heart Disease, Valve Disease, Heart,
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 0 - 50

Code: NCT06387446

Recruiting
Active & Responsive

Establishing Walking-related Digital Biomarkers in Rare Childhood Onset Progressive Neuromuscular Disorders

for
Spinal Muscular Atrophy Type 3,
Location: Boston MA, New York NY, Palo Alto CA
Sponsor: Columbia University

Sex: All

Age: 5+

Code: NCT06839469

Recruiting
Active & Responsive

Slow Heart Registry of Fetal Immune-mediated High Degree Heart Block

for
Heart Block Complete, Heart Block Second Degree
Location: Boston MA, New York NY, Washington DC, Halifax, Toronto,
Sponsor: The Hospital for Sick Children

Sex: Female

Age: 16 - 50

Code: NCT04559425

Recruiting

With its world-renowned healthcare network and prestigious medical research institutions, Boston is a premier destination for a wide range of clinical trials. Major centers such as Massachusetts General Hospital, Brigham and Women’s Hospital, Beth Israel Deaconess Medical Center, and the Dana-Farber Cancer Institute lead groundbreaking studies across various medical fields. These institutions are at the forefront of innovation, making Boston a hub for cutting-edge clinical research.

Why choose Boston for clinical trials?

Boston stands out as a leader in healthcare and life science, and has become an important destination for participants taking part in clinical trials. With world-class medical institutions and a diverse patient population, researchers can deliver more reliable and relevant results.

The city is also home to an innovative research ecosystem, strengthened by close collaborations between hospitals, universities, and biotech companies, making it a hub for cutting-edge clinical studies.

Common conditions studied in Boston

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