Paid Clinical Trials Boston
Discover 2,961 paid clinical trials in Boston, Massachusetts. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Multicenter Trial of Daily Chlorhexidine Bathing to Reduce Nosocomial Infections
Sponsor:
Hunter Holmes Mcguire Veteran Affairs Medical Center
Location:
Code:
NCT00502476
Conditions
Nosocomial Bacteremia
MRSA Colonization
MRSA Infection
VRE Colonization
VRE Infection
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Bathing with Chlorhexidine Impregnated Washcloths
A Therapeutic Experience Program (TEP) Study for Improvement of Gait in People With Multiple Sclerosis (MS)
Sponsor:
Helius Medical Inc
Location:
Code:
NCT05437276
Conditions
Gait Impairment Due to Mild/Moderate Multiple Sclerosis (MS)
Eligibility Criteria
Sex: All
Age: 22 - 65
Healthy Volunteers: Not accepted
Interventions
PoNS®
Mismatch vs. Standard Intervention During Memory Reconsolidation Blockade With Propranolol: Effect on Psychophysiological Reactivity During Traumatic Imagery
Sponsor:
Massachusetts General Hospital
Location:
Code:
NCT05853627
Conditions
Stress Disorders, Post-Traumatic
Eligibility Criteria
Sex: All
Age: 18 - 65
Healthy Volunteers: Not accepted
Interventions
Memory reactivation procedures
Propranolol
A Study Evaluating the Efficacy and Safety of Oral Etrasimod in the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease
Sponsor:
Pfizer
Location:
Code:
NCT04173273
Conditions
Crohn's Disease
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
Etrasimod
Placebo
Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU
Sponsor:
Brigham and Women's Hospital
Location:
Code:
NCT06538376
Conditions
Pulmonary Edema
Pneumonia
Atelectasis
Pleural Effusion
Acute Rejection of Lung Transplant (Disorder)
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Portable Dynamic Digital Radiography (DDR)
Endovascular Therapy for Low NIHSS Ischemic Strokes
Sponsor:
Emory University
Location:
Code:
NCT04167527
Conditions
Cerebral Ischemia
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Immediate mechanical thrombectomy(iMT) using EmboTrap Revascularization Device
Initial medical management (iMM)
TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention
Sponsor:
University Medical Center Nijmegen
Location:
Code:
NCT04294927
Conditions
BRCA1 Gene Mutation
BRCA2 Gene Mutation
RAD51C Gene Mutation
RAD51D Gene Mutation
BRIP1 Gene Mutation
Eligibility Criteria
Sex: Female
Age: 25 - 50
Healthy Volunteers: Not accepted
Interventions
Risk-reducing salpingectomy with delayed oophorectomy
Risk-reducing salpingo-oophorectomy
Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib Compared to Subcutaneous Adalimumab in Adult Participants With Moderate to Severe Rheumatoid Arthritis
Sponsor:
AbbVie
Location:
Code:
NCT05814627
Conditions
Rheumatoid Arthritis
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Upadacitinib
Adalimumab
Upadacitinib Matching Placebo
Adalimumab Matching Placebo
A Study in Participants With Advanced Cancers Associated With Expression of DLL3 (MK-6070-001/HPN328-4001)
Sponsor:
Harpoon Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Location:
Code:
NCT04471727
Conditions
Small-Cell Lung Cancer
Neuroendocrine Carcinoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
MK-6070
Atezolizumab
Ifinatamab Deruxtecan (I-DXd)
A Clinical Study That Will Measure How Well SEP-363856 Works and How Safe it is in Adults With Generalized Anxiety Disorder
Sponsor:
Otsuka Pharmaceutical Development & Commercialization, Inc.
Location:
Code:
NCT05729373
Conditions
Generalized Anxiety Disorder
Eligibility Criteria
Sex: All
Age: 18 - 65
Healthy Volunteers: Not accepted
Interventions
SEP-363856
Placebo
With its world-renowned healthcare network and prestigious medical research institutions, Boston is a premier destination for a wide range of clinical trials. Major centers such as Massachusetts General Hospital, Brigham and Women’s Hospital, Beth Israel Deaconess Medical Center, and the Dana-Farber Cancer Institute lead groundbreaking studies across various medical fields. These institutions are at the forefront of innovation, making Boston a hub for cutting-edge clinical research.
Why choose Boston for clinical trials?
Boston stands out as a leader in healthcare and life science, and has become an important destination for participants taking part in clinical trials. With world-class medical institutions and a diverse patient population, researchers can deliver more reliable and relevant results.
The city is also home to an innovative research ecosystem, strengthened by close collaborations between hospitals, universities, and biotech companies, making it a hub for cutting-edge clinical studies.
Common conditions studied in Boston
Boston is renowned for its extensive clinical research across a wide array of medical conditions, driven by its world-class hospitals and research institutions.
Cancer
Boston's Dana-Farber Cancer Institute, Massachusetts General Hospital Cancer Center, and other top institutions are renowned for conducting cutting-edge cancer research. They lead oncology clinical trials focusing on a wide array of cancers such as breast, lung, colorectal, and melanoma.
These trials explore innovative treatments, including CAR-T cell therapy, immune checkpoint inhibitors, precision oncology, and experimental drugs designed to target specific genetic mutations in tumors.
Cardiovascular disease
Boston is a leader in cardiovascular research, addressing diseases such as coronary artery disease, heart failure, hypertension, and atrial fibrillation. Institutions like the Brigham and Women’s Hospital Heart & Vascular Center and Beth Israel Deaconess Medical Center focus on clinical trials investigating new medications, minimally invasive surgical procedures, and medical devices like left ventricular assist devices (LVADs) and transcatheter aortic valve replacements (TAVR). Studies often explore novel biomarkers for early detection and prevention strategies.
Neurological disorders
Boston's status as a hub for neuroscience research is underscored by its extensive studies into Alzheimer’s disease, Parkinson’s disease, ALS (Lou Gehrig's disease), epilepsy, and multiple sclerosis (MS).
Major hospitals such as Massachusetts General Hospital and Boston Children's Hospital lead clinical trials on disease-modifying therapies, neuroprotective agents, and gene-editing technologies. Researchers also investigate new treatments for stroke recovery and traumatic brain injuries.
Autoimmune diseases
The city’s leading research centers conduct numerous trials targeting autoimmune conditions such as rheumatoid arthritis, lupus, and Crohn's disease. These trials frequently test advanced biologic therapies, monoclonal antibodies, and small molecule drugs designed to dampen the immune response or reset immune system function. Personalized approaches like precision immunotherapy and the use of stem cells are also areas of active exploration in Boston.
Diabetes and endocrine disorders
Boston has long been at the forefront of diabetes research, with a particular focus on innovative treatments for both Type 1 and Type 2 diabetes. Trials often explore new forms of insulin, artificial pancreas technologies, continuous glucose monitors, and regenerative medicine approaches like beta-cell transplantation. Endocrine research also spans conditions such as thyroid disorders, obesity, and metabolic syndrome.
Rare diseases
Boston’s research institutions are committed to tackling rare diseases, with several clinical trials focused on orphan diseases such as cystic fibrosis, Duchenne muscular dystrophy, and other rare genetic conditions. These trials often test gene therapies, CRISPR-based gene editing, and experimental drugs designed to address the underlying causes of these conditions.
Local regulations and guidelines
Clinical trials in Boston adhere to rigorous guidelines and regulations to ensure participant safety, ethical conduct, and scientific integrity. These trials must comply with federal standards set by the FDA and HHS, as well as the Common Rule for human research ethics. Institutions conducting clinical trials must have Institutional Review Boards (IRBs) that review and approve research protocols to ensure they prioritize participant rights and safety. Additionally, the informed consent process ensures that participants fully understand the risks and benefits before enrolling.
Massachusetts also enforces strict state-specific regulations, particularly through the Department of Public Health (DPH) and HIPAA guidelines for patient privacy. Researchers in Boston follow Good Clinical Practice (GCP) standards, and all clinical trials are required to register on ClinicalTrials.gov for transparency.
Benefits of participating in clinical trials
Participating in a clinical trial offers a unique chance to access cutting-edge treatments and therapies before they are widely available. During a clinical trial, participants benefit from expert care provided by top healthcare professionals, ensuring personalized attention and thorough monitoring throughout the study.
Clinical trial participation plays a crucial role in advancing medical research, often leading to groundbreaking discoveries in treatment and prevention. By joining a trial, individuals make a meaningful contribution to the development of new medical knowledge, ultimately improving future healthcare for others.
Worried about the risks of participating in a clinical trial? Read our comprehensive guide to gain insights into the potential outcomes of participating. Learn about potential risks, benefits, and safety considerations to make an informed decision about your participation in a clinical trial.
How to enroll in a clinical trial in Boston
Enrolling in a clinical trial through our platform is a straightforward and user-friendly process. Here's how to get started:
- Identify your trial: Use our intuitive search bar or filter options to locate clinical trials specific to requirements. This first step simplifies the process of finding relevant research studies tailored to your needs.
- Select your preferred location: To find trials conveniently located near you, simply input your preferred location into the dedicated filter bar on the left-hand side of the page.
- Explore study details: For in-depth information about each study, simply click the “Learn More” button. This will provide you with comprehensive details about the trial, including objectives, procedures, and eligibility criteria.
- Complete the health profile: After clicking on the “Get started” button you will be taken to our efficient 5-step application process to provide important health information. This helps us match you with the clinical trial that best fits your needs.
- Submit the application: After completing the application, send it in. A clinical trial coordinator will review it and contact you regarding the possibility of participation.