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Paid Clinical Trials Boston

Discover 3,070 paid clinical trials in Boston, Massachusetts. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Real-world Experience of Catheter Ablation for the Treatment of Arrhythmias

for
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation,
Location: Boston MA, Portland ME, Poughkeepsie NY, New York NY,
Sponsor: Heart Rhythm Clinical and Research Solutions, LLC

Sex: All

Age: 18+

Code: NCT04088071

Recruiting

JAG201 Gene Therapy Study in Children & Adults With SHANK3 Haploinsufficiency

for
SHANK3 Haploinsufficiency, Phelan-McDermid Syndrome
Location: Boston MA, New York NY, Chicago IL
Sponsor: Jaguar Gene Therapy, LLC

Sex: All

Age: 2 - 9

Code: NCT06662188

Phase1, Phase2, Recruiting

A Long-term, Post-marketing Safety Study of Palynziq in Patients With PKU (PALace)

for
Phenylketonuria (PKU)
Location: Boston MA, Pittsburgh PA, Indianapolis IN, Chicago IL,
Sponsor: BioMarin Pharmaceutical

Sex: All

Age: 0+

Code: NCT05813678

Recruiting

A Study of Navlimetostat (BMS-986504) Alone or in Combination With Izalontamab Brengitecan in Participants With Pre-treated Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) With Homozygous MTAP Deletion or MTAP Loss (MountainTAP-9)

for
Carcinoma, Non-Small-Cell Lung
Location: Boston MA, New York NY, Canton OH, Detroit MI,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT06855771

Phase2, Recruiting

[18F]PI-2620 Phase 3 Histopathological Study

for
Alzheimer Disease
Location: Braintree MA, Lebanon NH, East Syracuse NY, Syracuse NY,
Sponsor: Lantheus Biosciences Ltd.

Sex: All

Age: 50+

Code: NCT05641688

Phase3, Recruiting

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Metastatic Leiomyosarcoma Biomarker Protocol

for
Leiomyosarcoma
Location: Boston MA, New York NY, Columbus OH, Ann Arbor MI,
Sponsor: University of Michigan Rogel Cancer Center

Sex: All

Age: 0+

Code: NCT05653388

Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of RLS-0071 in Newborns With Moderate or Severe Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic Hypothermia

for
Hypoxic-Ischemic Encephalopathy
Location: Boston MA, Morgantown WV, Cleveland OH, Durham NC,
Sponsor: ReAlta Life Sciences, Inc.

Sex: All

Age: 0

Code: NCT05778188

Phase2, Recruiting

Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs

for
Failed or Difficult Intubation, Sequela, Intubation; Difficult,
Location: Boston MA, Providence RI, Springfield MA, Lebanon NH,
Sponsor: Children's Hospital of Philadelphia

Sex: All

Age: 0+

Code: NCT02493478

Recruiting

A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma

for
Neoplasms, Head and Neck
Location: Worcester MA, Farmington CT, New Haven CT, The Bronx NY,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT06256588

Phase3, Recruiting

Pathways, Risk Factors, and mOleculeS to Prevent Early-onset Colorectal Tumors

for
Colorectal Cancer Prevention, Colorectal Adenoma
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18 - 50

Code: NCT07095517

Phase1, Recruiting

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

for
KRAS-mutant Non-small Cell Lung Cancer (NSCLC),
Location: Boston MA, Philadelphia PA, Fairfax VA, Tampa FL,
Sponsor: Kestrel Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07458347

Phase1, Recruiting

CRICKET: Critical Events in Anaesthetised Kids Undergoing Tracheal Intubation

for
Intubation Complication, Adverse Events
Location: Boston MA, Montreal, Philadelphia PA, Toronto
Sponsor: Thomas Riva

Sex: All

Age: 0 - 16

Code: NCT05804188

Recruiting

Perinatal Brain Injury: Potential of Innovative NIRS to Optimize Hypothermia

for
Hypoxic Ischemic Brain Injury, Neonatal Encephalopathy
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 0 - 2

Code: NCT02793999

Recruiting

BILe Acid-gut Microbiome Axis MODification Through Diet Education for Colorectal Cancer Prevention

for
Colorectal Cancer Prevention, Colorectal Adenoma
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18 - 70+

Code: NCT07162337

Recruiting

Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer

for
Astrocytoma, IDH-Mutant, Grade 3
Location: Boston MA, Sanford ME, Waterford CT, Scarborough ME,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 12+

Code: NCT07215910

Phase3, Recruiting

Addressing Cancer Care Equity With Social Determinants of Health Screening and Early Intervention

for
Leukemia, Acute
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT07671209

Recruiting

Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)

for
Acute Myeloid Leukemia,
Location: Boston MA, Burlington MA, Peabody MA, Providence RI,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 59

Code: NCT05554406

Phase2, Recruiting

DATO-BASE: DATOpotamab-deruxtecan for Breast Cancer Brain metAstaSEs

for
Breast Cancer, Breast Cancer Female,
Location: Boston MA, Durham NC, Miami FL
Sponsor: Nancy Lin, MD

Sex: All

Age: 18+

Code: NCT06176261

Phase2, Recruiting

Cognition and the Immunology of Postoperative Outcomes

for
Cognitive Impairment, Frail Elderly Syndrome, Delirium, Surgery
Location: Boston MA
Sponsor: Brigham and Women's Hospital

Sex: All

Age: 65+

Code: NCT04792983

Recruiting

VS-6766+Abema+Fulv in Met HR+/HER- BC

for
Breast Cancer, Hormone Receptor-positive Breast Cancer,
Location: Boston MA
Sponsor: Adrienne G. Waks

Sex: All

Age: 18+

Code: NCT05608252

Phase1, Phase2, Recruiting

With its world-renowned healthcare network and prestigious medical research institutions, Boston is a premier destination for a wide range of clinical trials. Major centers such as Massachusetts General Hospital, Brigham and Women’s Hospital, Beth Israel Deaconess Medical Center, and the Dana-Farber Cancer Institute lead groundbreaking studies across various medical fields. These institutions are at the forefront of innovation, making Boston a hub for cutting-edge clinical research.

Why choose Boston for clinical trials?

Boston stands out as a leader in healthcare and life science, and has become an important destination for participants taking part in clinical trials. With world-class medical institutions and a diverse patient population, researchers can deliver more reliable and relevant results.

The city is also home to an innovative research ecosystem, strengthened by close collaborations between hospitals, universities, and biotech companies, making it a hub for cutting-edge clinical studies.

Common conditions studied in Boston

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