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Paid Clinical Trials Boston

Discover 3,070 paid clinical trials in Boston, Massachusetts. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

A Study of Brenipatide in Adult Participants With Major Depressive Disorder

for
Depressive Disorder, Major
Location: Boston MA, Watertown MA, Foxborough MA, New Haven CT,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 70+

Code: NCT07412756

Phase3, Recruiting
Active & Responsive

A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder

for
Alcohol Use Disorder
Location: Boston MA, Foxborough MA, The Bronx NY, Philadelphia PA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 70+

Code: NCT07219966

Phase3, Recruiting
Active & Responsive

A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

for
Treatment Resistant Depression
Location: Watertown MA, Springfield MA, New York NY, Eatontown NJ,
Sponsor: atai Therapeutics, Inc.

Sex: All

Age: 18 - 65

Code: NCT06524830

Phase2, Recruiting
Active & Responsive

A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

for
Major Depressive Disorder (MDD), Depression in Adults,
Location: Boston MA, Watertown NY, New Haven CT, New York NY,
Sponsor: Cybin IRL Limited

Sex: All

Age: 18 - 70+

Code: NCT06793397

Phase3, Recruiting
Active & Responsive

A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)

for
Major Depressive Disorder
Location: Boston MA, Worcester MA, New York NY, Philadelphia PA,
Sponsor: Definium Therapeutics US, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07592689

Phase3, Recruiting

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Active & Responsive

ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

for
Major Depressive Disorder (MDD),
Location: Watertown MA, Worcester MA, Brooklyn NY,
Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All

Age: 18 - 65

Code: NCT07284667

Phase2, Recruiting
Active & Responsive

A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)

for
Alzheimer Disease
Location: Watertown MA, Methuen MA, Albany NY,
Sponsor: Alpha Cognition, Inc

Sex: All

Age: 50+

Code: NCT07633470

Recruiting
Active & Responsive

A VIRTUAL Three-month Intervention Study of the Effects of a Smartphone Application (HippoCamera) on Memory in Teens and Young Adults With Down Syndrome

for
Memory Replay, HippoCamera
Location: Chestnut Hill MA
Sponsor: Boston College

Sex: All

Age: 15 - 35

Code: NCT07008989

Recruiting
Active & Responsive

A Prospective Controlled Study to Evaluate the Safety and Effectiveness of Thermage® FLX Radiofrequency Treatment

for
Wrinkle, Lax Skin, Lines Skin
Location: Chestnut Hill MA, New York NY, Chicago IL, Houston TX,
Sponsor: Bausch Health Americas, Inc.

Sex: All

Age: 30 - 60

Code: NCT07187297

Recruiting
Active & Responsive

Treatment of Perioral Wrinkles Using Topical Poly-L-lactic Acid and Microneedling Device

for
Perioral Wrinkles
Location: Chestnut Hill MA
Sponsor: Skincare Physicians of Chestnut Hill

Sex: All

Age: 40 - 70

Code: NCT07225348

Recruiting
Active & Responsive

Safety and Effectiveness of Mosaic for the Treatment of Midface Volume Deficit

for
Midface Volume Deficit
Location: Chestnut Hill MA, Huntington Station NY, Bryn Mawr PA,
Sponsor: Helios Aesthetics Inc.

Sex: All

Age: 22+

Code: NCT07710443

Recruiting
Active & Responsive

Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy

for
Diabetic Peripheral Neuropathic Pain
Location: Boston MA, East Greenwich RI, Waterbury CT,
Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All

Age: 18 - 70+

Code: NCT07231419

Phase3, Recruiting
Active & Responsive

Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs)

for
Generalized Myasthenia Gravis
Location: Boston MA, New Haven CT, New Hyde Park NY,
Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT04202341

Recruiting
Active & Responsive

A Study of the Safety and Effectiveness of DDP733 in Treating IBS With Constipation in Females

for
Irritable Bowel Syndrome
Location: Boston MA, Brooklyn NY, Ottawa, Laurel MD,
Sponsor: Dynogen Pharmaceuticals

Sex: Female

Age: 18 - 65

Code: NCT00547469

Phase2, Phase3, Recruiting
Active & Responsive

Cannabidiol Solution for the Treatment of Behavioral Symptoms in Older Adults With Mild Cognitive Impairment or Alzheimer's Dementia

for
Alzheimer Disease, Anxiety, Agitation,Psychomotor
Location: Belmont MA
Sponsor: Mclean Hospital

Sex: All

Age: 55 - 70+

Code: NCT04075435

Early_phase1, Recruiting
Active & Responsive

Assessing the Impact of Cannabidiol for Anxiety and Depression in Bipolar Disorder

for
Bipolar Disorder
Location: Belmont MA
Sponsor: Mclean Hospital

Sex: All

Age: 18 - 65

Code: NCT05457465

Phase2, Recruiting
Active & Responsive

PAIN: a Project Assessing the Impact of a Novel Cannabinoid Product

for
Chronic Pain
Location: Belmont MA
Sponsor: Staci Gruber, Ph.D.

Sex: All

Age: 21+

Code: NCT03984565

Phase2, Recruiting
Active & Responsive

Mechanisms and Predictors of Change in App-Based Mindfulness Training for Adolescents

for
Rumination
Location: Belmont MA
Sponsor: Mclean Hospital

Sex: All

Age: 13 - 18

Code: NCT04697966

Recruiting
Active & Responsive

Neural Correlates of Stress and Perceived Control in Adolescent Depression

for
Major Depressive Disorder
Location: Belmont MA
Sponsor: Mclean Hospital

Sex: Female

Age: 14 - 18

Code: NCT04788524

Recruiting
Active & Responsive

Mechanisms of Exposure Therapy for OCD

for
Obsessive-Compulsive Disorder
Location: Belmont MA, San Diego CA
Sponsor: Mclean Hospital

Sex: All

Age: 18 - 65

Code: NCT06173752

Recruiting

With its world-renowned healthcare network and prestigious medical research institutions, Boston is a premier destination for a wide range of clinical trials. Major centers such as Massachusetts General Hospital, Brigham and Women’s Hospital, Beth Israel Deaconess Medical Center, and the Dana-Farber Cancer Institute lead groundbreaking studies across various medical fields. These institutions are at the forefront of innovation, making Boston a hub for cutting-edge clinical research.

Why choose Boston for clinical trials?

Boston stands out as a leader in healthcare and life science, and has become an important destination for participants taking part in clinical trials. With world-class medical institutions and a diverse patient population, researchers can deliver more reliable and relevant results.

The city is also home to an innovative research ecosystem, strengthened by close collaborations between hospitals, universities, and biotech companies, making it a hub for cutting-edge clinical studies.

Common conditions studied in Boston

Local regulations and guidelines

Benefits of participating in clinical trials

How to enroll in a clinical trial in Boston