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Paid Clinical Trials Boston

Discover 3,070 paid clinical trials in Boston, Massachusetts. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

for
Non-Small Cell Lung Cancer
Location: Boston MA, Stony Brook NY, Montreal, Trois-Rivieres,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06357533

Phase3, Recruiting

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

for
Heart Failure and Impaired Kidney Function
Location: Boston MA, Worcester MA, Providence RI, Clifton Park NY,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06307652

Phase3, Recruiting

A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic Inflammatory Myopathies (Polymyositis and Dermatomyositis)

for
Polymyositis, Dermatomyositis
Location: Boston MA, New Haven CT, Great Neck NY, Montreal,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06455449

Phase3, Recruiting

A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

for
Chronic Kidney Disease and Hypertension
Location: Boston MA, Braintree MA, Worcester MA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06742723

Phase3, Recruiting

A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE

for
Lupus Erythematosus, Systemic
Location: Boston MA, New York NY, Syracuse NY, Chapel Hill NC,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70

Code: NCT06897930

Phase1, Phase2, Recruiting

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DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

for
Endometrial Cancer
Location: Boston MA, Providence RI, Lebanon NH, Hackensack NJ,
Sponsor: AstraZeneca

Sex: Female

Age: 18+

Code: NCT06989112

Phase3, Recruiting

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

for
Heart Failure
Location: Boston MA, Roslindale MA, Waterbury CT, Bridgeport CT,
Sponsor: AstraZeneca

Sex: All

Age: 40+

Code: NCT06677060

Phase3, Recruiting

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

for
COPD (Chronic Obstructive Pulmonary Disease)
Location: Boston MA, Albany NY, New Windsor NY, Massapequa NY,
Sponsor: AstraZeneca

Sex: All

Age: 40 - 70+

Code: NCT06283966

Phase3, Recruiting

Flo Digital Contraceptive Study

for
Contraception Use
Location: Boston MA
Sponsor: Flo Health Inc.

Sex: Female

Age: 18+

Code: NCT07630064

Recruiting

Night Owl Sleep Study: The Effect of Sleep on Fecal Microbiota

for
Sleep
Location: Boston MA
Sponsor: Danisco

Sex: All

Age: 20 - 40

Code: NCT07243574

Recruiting

The Short Sleep Study

for
Short Sleepers
Location: Boston MA, Garden City NY, Miami FL, Houston TX
Sponsor: Danisco

Sex: All

Age: 20 - 50

Code: NCT07567560

Recruiting

NA-831, Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection

for
Coronavirus Infection, Severe Acute Respiratory Infection,
Location: Boston MA, Bronx NY, New York NY, Newark NJ,
Sponsor: Biomed Industries, Inc.

Sex: All

Age: 18 - 70+

Code: NCT04452565

Phase2, Phase3, Recruiting

Safety and Efficacy of Brilaroxazine (RP5063) in Schizophrenia

for
Schizophrenia
Location: Boston MA, Gaithersburg MD, Chicago IL, Decatur GA,
Sponsor: Reviva Pharmaceuticals

Sex: All

Age: 18 - 65

Code: NCT05184335

Phase3, Recruiting

Remote Monitoring of High-Risk Patients With Chronic Cardiopulmonary Diseases

for
Congestive Heart Failure, Asthma,
Location: Boston MA
Sponsor: Institute of Bioengineering and Bioimaging (IBB)

Sex: All

Age: 18+

Code: NCT04825067

Recruiting

A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

for
Graves' Disease
Location: Boston MA, Monroe NY, Pottstown PA, Newark DE,
Sponsor: Immunovant Sciences GmbH

Sex: All

Age: 18 - 70+

Code: NCT06727604

Phase2, Recruiting

Two Post-Operative Pain Protocols at Discharge for Orthopaedic Patients

for
Orthopaedic Related Pain (Musculoskeletal Pain), Opioid, Pain,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT07265557

Recruiting

Usnoflast Neuromuscular Investigation for Treatment Efficacy in Amyotrophic Lateral Sclerosis

for
Amyotrophic Lateral Sclerosis (ALS)
Location: Boston MA, New Britain CT, Richmond VA, Pittsburgh PA,
Sponsor: Zydus Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT07023835

Phase2, Recruiting

A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

for
HNSCC, ESCC, Esophageal Adenocarcinoma, Gastric Adenocarcinoma,
Location: Boston MA, New Haven CT, Hackensack NJ, Philadelphia PA,
Sponsor: Normunity AccelCo, Inc.

Sex: All

Age: 18+

Code: NCT07182149

Phase1, Recruiting

A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy

for
Non-obstructive Hypertrophic Cardiomyopathy
Location: Boston MA, Burlington MA, New York NY, Philadelphia PA,
Sponsor: Imbria Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT07023614

Phase2, Recruiting

A Study of PHN-012 in Patients With Advanced Solid Tumors

for
Colon Cancer, Pancreatic Cancer, Lung Cancer (NSCLC),
Location: Boston MA, Washington D.C. DC, Fairfax VA, Durham NC,
Sponsor: Pheon Therapeutics

Sex: All

Age: 18+

Code: NCT07127874

Phase1, Recruiting

With its world-renowned healthcare network and prestigious medical research institutions, Boston is a premier destination for a wide range of clinical trials. Major centers such as Massachusetts General Hospital, Brigham and Women’s Hospital, Beth Israel Deaconess Medical Center, and the Dana-Farber Cancer Institute lead groundbreaking studies across various medical fields. These institutions are at the forefront of innovation, making Boston a hub for cutting-edge clinical research.

Why choose Boston for clinical trials?

Boston stands out as a leader in healthcare and life science, and has become an important destination for participants taking part in clinical trials. With world-class medical institutions and a diverse patient population, researchers can deliver more reliable and relevant results.

The city is also home to an innovative research ecosystem, strengthened by close collaborations between hospitals, universities, and biotech companies, making it a hub for cutting-edge clinical studies.

Common conditions studied in Boston

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